Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Lauren Blech"'
Autor:
Lauren Blech, Volodymyr Kostenko, Guido J. Jenniskens, Pavel Sul, Ella G. Frolova, Christy Harry, Amit Vasanji, Irene Krukovets, Edward F. Plow, Olga Stenina-Adognravi, Judith A. Drazba, Carla Drumm
Publikováno v:
Matrix Biology. 37:35-48
Thrombospondins (TSPs) are multifunctional proteins that are deposited in the extracellular matrix where they directly affect the function of vascular and other cell types. TSP-4, one of the 5 TSP family members, is expressed abundantly in tendon and
Autor:
Nikolai A. Sopko, Ella G. Frolova, Irene Krukovets, Zoran B. Popović, Jianbo Li, Mukesh K. Jain, Edward F. Plow, Olga I. Stenina, Lauren Blech, Marc S. Penn, Amit Vasanji, Carla Drumm
Publikováno v:
The FASEB Journal. 26:2363-2373
Thrombospondin-4 (TSP-4) expression increases dramatically in hypertrophic and failing hearts in rodent models and in humans. The aim of this study was to address the function of TSP-4 in the heart. TSP-4-knockout (Thbs4−/−) and wild-type (WT) mi
Autor:
Irene Krukovets, Carla Drumm, Ella G. Frolova, Lauren Blech, Elzbieta Pluskota, Jonathan D. Smith, Olga I. Stenina, Paul Bornstein, Edward F. Plow, Maria Febbraio, Tim Burke
Publikováno v:
Circulation Research. 107:1313-1325
Rationale: Thrombospondin (TSP)-4 is an extracellular protein that has been linked to several cardiovascular pathologies. However, a role for TSP-4 in vascular wall biology remains unknown. Objective: We have examined the effects of TSP-4 gene ( Thbs