Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Lauren B, Peiffer"'
Autor:
Lauren B. Peiffer, James R. White, Carli B. Jones, Rachel E. Slottke, Sarah E. Ernst, Amy E. Moran, Julie N. Graff, Karen S. Sfanos
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 32, Iss , Pp 100822- (2022)
Recent studies in cancer patients and animal models demonstrate that intestinal microbiota influence the therapeutic efficacy of cancer treatments, including immune checkpoint inhibition. However, no studies to-date have investigated relationships be
Externí odkaz:
https://doaj.org/article/e3769f5586d74baa8303d87a6c921ba4
Autor:
Lauren B. Peiffer, Jessica Hicks, Rebecca Y. Sosa, Angelo M. De Marzo, Karen S. Sfanos, Janielle P. Maynard
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
The 5-year survival rate for patients diagnosed with distant metastatic prostate cancer in the United States is 30.6%. Therefore, there is a great need to develop in vivo model systems to study prostate cancer metastasis and to test potential therape
Externí odkaz:
https://doaj.org/article/d5fb3d77abd240289fd047095a2786a4
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Short read 16 S rRNA amplicon sequencing is a common technique used in microbiome research. However, inaccuracies in estimated bacterial community composition can occur due to amplification bias of the targeted hypervariable region. A potential solut
Externí odkaz:
https://doaj.org/article/f13badecf90c403c94baacef2e91c574
Autor:
Qizhi Zheng, Angelo M. De Marzo, Jiayu Chen, Avi Z. Rosenberg, Michael C. Haffner, Busra Ozbek, Lauren B. Peiffer, Moshe Levi, Jessica L. Hicks, Srinivasan Yegnasubramanian, Javier A. Baena Del Valle, Xiaoxin X. Wang
Publikováno v:
Am J Pathol
Mitochondria regulate ATP production, metabolism, and cell death. Alterations in mitochondrial DNA (mtDNA) sequence and copy number are implicated in aging and organ dysfunction in diverse inherited and sporadic diseases. Because most measurements of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82337b73e9a0bf8a63997a2a1783e446
https://doi.org/10.1016/j.ajpath.2020.03.018
https://doi.org/10.1016/j.ajpath.2020.03.018
Publikováno v:
Radiation Research. 197
Beyond low-Earth orbit, space radiation poses significant risks to astronaut health. Previous studies have shown that the microbial composition of the gastrointestinal (GI) microbiome changes upon exposure to high-linear energy transfer radiation. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc9d779aa9126a4d4ae986fa592ec97c
https://doi.org/10.1667/rade-20-00285.1
https://doi.org/10.1667/rade-20-00285.1
Autor:
Jessica L. Hicks, Tamara L. Lotan, Angelo M. De Marzo, Ayanna M Carter, Lauren B. Peiffer, Luke Mummert, Rebecca Y Sosa, Jiayun Lu, Corinne E. Joshu, Karen S. Sfanos, Ryan Kempski, Igor Vidal, Tamirat Ali, Janielle P. Maynard
Publikováno v:
J Pathol
Prostate cancer (PCa) remains a leading cause of cancer-related deaths in American men and treatment options for metastatic PCa are limited. There is a critical need to identify new mechanisms that contribute to PCa progression, that distinguish beni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a11d0bec6afc7d1114678d274c82d074
https://pubmed.ncbi.nlm.nih.gov/34652816
https://pubmed.ncbi.nlm.nih.gov/34652816
Short read 16S rRNA amplicon sequencing is a common technique used in microbiome research. However, inaccuracies in estimated bacterial community composition can occur due to amplification bias of the targeted hypervariable region. A potential soluti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7bd3f86324a54e5227f0958289f6179d
https://doi.org/10.1101/2021.06.17.448728
https://doi.org/10.1101/2021.06.17.448728
Autor:
Janielle P. Maynard, Igor Vidal, Kempski R, Sosa R, Carter Am, Luke Mummert, Jiayun Lu, Karen S. Sfanos, De Marzo Am, Tamara L. Lotan, Jessica L. Hicks, Corinne E. Joshu, Lauren B. Peiffer, Ali T
Prostate cancer (PCa) remains a leading cause of cancer-related deaths in American men and treatment options for metastatic PCa are limited. There is a critical need to identify new mechanisms that contribute to PCa progression, that distinguish beni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce2e43db6aa7066b7ec9f95f57571f02
https://doi.org/10.1101/2021.06.04.446195
https://doi.org/10.1101/2021.06.04.446195
Autor:
Lauren B. Peiffer, Kenneth J. Pienta, James R. White, Sarah E. Ernst, Mark C. Markowski, Karen S. Sfanos, Ashley E. Ross, Emmanuel S. Antonarakis
Publikováno v:
Prostate Cancer and Prostatic Diseases
Background It is well known that the gastrointestinal (GI) microbiota can influence the metabolism, pharmacokinetics, and toxicity of cancer therapies. Conversely, the effect of cancer treatments on the composition of the GI microbiota is poorly unde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ed77c4dbac4533b5237fe6f90284351
https://doi.org/10.1038/s41391-018-0061-x
https://doi.org/10.1038/s41391-018-0061-x
Publikováno v:
Prostate Cancer and Prostatic Diseases. 21:345-354
The human microbiome may influence prostate cancer initiation and/or progression through both direct and indirect interactions. To date, the majority of studies have focused on direct interactions including the influence of prostate infections on pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84dca7befc071bb30605f142db9c89f3
https://doi.org/10.1038/s41391-018-0041-1
https://doi.org/10.1038/s41391-018-0041-1