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pro vyhledávání: '"Lauren Appell"'
Publikováno v:
Transplantation and Cellular Therapy. 29:S366-S367
Autor:
Marie Burdine, Ana Azevedo-Pouly, Lauren Appell, Melanie Barker, Zachary Waldrip, Lyle Burdine
Publikováno v:
The Journal of Immunology. 208:55.15-55.15
Antigen-mediated activation of naïve CD8+ T cells and their differentiation into cytotoxic cells is regulated by a series of signaling mechanisms designed to maintain T cell homeostasis and proper immune responses. Given that cytotoxic CD8+ T cells
Publikováno v:
Blood. 138:2768-2768
Hematopoietic stem cell transplantation (HCT) is an effective therapeutic option for many cancers and disorders of immune dysfunction. However, acute graft versus host disease (GVHD) remains a morbid complication of HCT, caused by donor T cells attac