Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Lauren A. Trepanier"'
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 38, Iss 3, Pp 1659-1665 (2024)
Abstract Background Multicentric lymphoma (ML) in dogs resembles non‐Hodgkin lymphoma (NHL) in humans. Human NHL is associated with multiple environmental exposures, including to radon and volatile organic compounds (VOCs). Hypothesis/Objectives Th
Externí odkaz:
https://doaj.org/article/2737c8d2c02244a09bcde57b98f7362f
Publikováno v:
Journal of Clinical and Translational Science, Vol 8 (2024)
Abstract Introduction: Major risk factors for urothelial cell carcinoma (UCC) in people are smoking and occupational exposures. However, up to 30% of human UCC risk is still unexplained. Pet dogs develop UCC that models the clinical behavior of musc
Externí odkaz:
https://doaj.org/article/37fdd8ae9ebb4cd0abaf868c7b5ad3c6
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 37, Iss 3, Pp 960-967 (2023)
Abstract Background Greyhounds have been reported to have hyperhomocysteinemia (HHC), but the underlying mechanisms and clinical implications are unclear. Hypothesis Our primary aim was to assess serum concentrations of homocysteine (HCy) and related
Externí odkaz:
https://doaj.org/article/535264fee8214eeebab4a0762576cc92
Publikováno v:
Canine Medicine and Genetics, Vol 9, Iss 1, Pp 1-10 (2022)
Plain English Summary Lymphoma is a common cancer affecting dogs, particularly Golden Retrievers. By identifying risk factors for lymphoma, work can be done to reduce harmful exposures or increase monitoring among dogs at a higher risk of disease. Us
Externí odkaz:
https://doaj.org/article/4e2691d3d6e64b548e62d5c2b4f8d5f0
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 36, Iss 2, Pp 576-579 (2022)
Abstract Background Acute hepatopathy secondary to administration of zonisamide has been reported in 2 dogs, but overall incidence of hepatopathy is unknown. Objective To characterize the incidence of hepatopathy in dogs administered zonisamide PO. A
Externí odkaz:
https://doaj.org/article/45fa996c5f574621b8af0889ee22183d
Autor:
Kaitlyn Craun, Joanne Ekena, James Sacco, Tao Jiang, Alison Motsinger‐Reif, Lauren A. Trepanier
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 34, Iss 5, Pp 2068-2077 (2020)
Abstract Background Non‐Hodgkin lymphoma in humans is associated with environmental chemical exposures, and risk is enhanced by genetic variants in glutathione S‐transferases (GST) enzymes. Objective We hypothesized that boxer dogs, a breed at ri
Externí odkaz:
https://doaj.org/article/b52c5f1dedcb421294b1f1d546fb7cd3
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 33, Iss 3, Pp 1414-1422 (2019)
Abstract Introduction Transitional cell carcinoma (TCC) in humans is associated with environmental exposures and variants in glutathione S‐transferase (GST) genes. Scottish Terriers have a high breed risk for TCC, but the relationship between genet
Externí odkaz:
https://doaj.org/article/548fe6c6c54f48a5a0e3084dd88bbc41
Publikováno v:
American Journal of Veterinary Research. :1-6
OBJECTIVE To determine whether metronidazole (MTZ), at recommended therapeutic dosages in dogs, induces peripheral blood cell (PMBC) genotoxicity, using the γ-H2AX assay as a sensitive measure of DNA breaks. The secondary aim was to assess dose-depe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f53ca41c30e14d903628287d182c1f69
https://doi.org/10.2460/ajvr.22.07.0112
https://doi.org/10.2460/ajvr.22.07.0112
Publikováno v:
Vet Comp Oncol
Human urothelial cell carcinoma (UCC) and non-Hodgkin lymphoma are considered environmental cancers in people, but less is known about environment risk for UCC and lymphoma in dogs. The objective of this study was to determine whether dogs with these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::558e1e40578dfdbc6653279452077627
https://doi.org/10.1111/vco.12771
https://doi.org/10.1111/vco.12771
Publikováno v:
Journal of Feline Medicine and Surgery. 23:692-699
Objectives Oxidative stress contributes to chronic kidney disease (CKD) progression in humans and rodent models; F2-isoprostanes (F2-IsoPs) are established biomarkers of oxidative stress. Our primary aim was to evaluate plasma F2-IsoPs in cats with I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d63ce58016202531937795a1a771879
https://doi.org/10.1177/1098612x20969358
https://doi.org/10.1177/1098612x20969358