Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Lauren A. Mortimer"'
Autor:
Donald S. Anson, Yazad Irani, Douglas G.A. Parker, Lucas M. Bachmann, Lauren A. Mortimer, Claude Kaufmann, Keryn A. Williams, Helen M. Brereton
Publikováno v:
Current Eye Research. 42:1426-1434
To evaluate the gene transfer of the interleukin (IL)-10 cytokine as a treatment modality for prolonging limbal allograft survival in a rat model.Adenoviral (AV) and lentiviral (LV) vectors were produced for ex vivo gene transfer into limbal graft ti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f920d603699b63e53adf23a4e0ebb28
https://doi.org/10.1080/02713683.2017.1344714
https://doi.org/10.1080/02713683.2017.1344714
Autor:
Emily Pulford, Keryn A. Williams, Lisa M. Butler, Sonja Klebe, Lauren A. Mortimer, Yazad Irani, Swati Irani
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0221566 (2019)
PLoS ONE
PLoS ONE
Sex-based differences in susceptibility have been reported for a number of neovascular ocular diseases. We quantified corneal neovascularization, induced by superficial silver nitrate cautery, in male and female inbred albino Sprague-Dawley, inbred a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ce4353c0af5681779b274f6f5dc773c
https://doaj.org/article/b5affa225815465bade5fc586f29125c
https://doaj.org/article/b5affa225815465bade5fc586f29125c
Autor:
Pierre Scotney, Yazad Irani, Keryn A. Williams, Sonja Klebe, Lauren A. Mortimer, Andrew D. Nash
Publikováno v:
Investigative Opthalmology & Visual Science. 58:3404
Purpose We tested the ability of an antibody fragment with specificity for vascular endothelial growth factor-B (VEGF-B) to regress nascent and established corneal blood vessels in the rat. Methods A single chain variable antibody fragment (scFv) wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23b6a0d34c623cd5c7dc50666ef76cdd
https://doi.org/10.1167/iovs.16-21343
https://doi.org/10.1167/iovs.16-21343
Autor:
Peter J. Cowan, Sonja Klebe, Lauren A. Mortimer, Keryn A. Williams, Yazad Irani, Helen M. Brereton, Miriam C Keane, Sarah Louise Appleby
Publikováno v:
Journal of immunological methods. 397(1-2)
It is often desirable to co-express a reporter protein with a potential therapeutic protein, to verify correct targeting of an expression strategy. Vectors containing a viral self-processing 2A sequence have been reported to drive equimolar expressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f3f6848eb34773b2d1f873f491cf096
https://pubmed.ncbi.nlm.nih.gov/23999208
https://pubmed.ncbi.nlm.nih.gov/23999208
Autor:
Kirsty Kirk, Lauren A. Mortimer, Keryn A. Williams, Douglas J. Coster, Claire F. Jessup, Chuan K Tan, Helen M. Brereton, Sarah Louise Appleby
Publikováno v:
The British journal of ophthalmology. 97(1)
To investigate whether expression of an anti-CD4 antibody fragment (scFv) by a lentivector-transduced donor cornea can prolong rat corneal allograft survival. Methods Inbred Fischer 344 rats received penetrating corneal allografts from Wistar-Furth d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3fef1125d48220b1d2f57623c0a4b7f
https://pubmed.ncbi.nlm.nih.gov/23172880
https://pubmed.ncbi.nlm.nih.gov/23172880