Zobrazeno 1 - 10
of 126
pro vyhledávání: '"Lauren A. May"'
Autor:
Paige M. Krupa, Guilherme R. Lotufo, Erik J. Mylroie, Lauren K. May, Kurt A. Gust, Ashley N. Kimble, Michael G. Jung, Jonna A. Boyda, Natàlia Garcia-Reyero, David W. Moore
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 241, Iss , Pp 113838- (2022)
Perfluorooctane sulfonic acid (PFOS) is a ubiquitous and persistent contaminant in aquatic ecosystems. Chronic toxicity information for aquatic organisms is limited, therefore we conducted chronic PFOS toxicity tests for four model organisms commonly
Externí odkaz:
https://doaj.org/article/23b403846b8e4fa785f359d22d6d2db3
Autor:
Cheng Xue Qin, Lauren T. May, Patrick M. Sexton, Aaron J. DeBono, Jonathan B. Baell, Arthur Christopoulos, Rebecca H. Ritchie
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-4 (2018)
Externí odkaz:
https://doaj.org/article/f7968923b6824c2eabf9b7a299f1a489
Publikováno v:
Pediatric Radiology. 53:509-522
Autor:
Cheng Xue Qin, Lauren T. May, Renming Li, Nga Cao, Sarah Rosli, Minh Deo, Amy E. Alexander, Duncan Horlock, Jane E. Bourke, Yuan H. Yang, Alastair G. Stewart, David M. Kaye, Xiao-Jun Du, Patrick M. Sexton, Arthur Christopoulos, Xiao-Ming Gao, Rebecca H. Ritchie
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
G Protein-Coupled Receptors (GPCRs) can adopt different conformations, each linked to distinct cellular outcomes. Here the authors show that compound 17b, a novel agonist of the GPCR family member FPR, robustly activates cardioprotective but not detr
Externí odkaz:
https://doaj.org/article/662689059cf2432b82994c3add7656fb
Publikováno v:
Purinergic Signalling. 18:359-381
Alzheimer’s disease (AD) is the most common dementia in the elderly and its increasing prevalence presents treatment challenges. Despite a better understanding of the disease, the current mainstay of treatment cannot modify pathogenesis or effectiv
Autor:
Jon Kyle Awalt, Anh T.N. Nguyen, Tim J. Fyfe, Bui San Thai, Paul J. White, Arthur Christopoulos, Manuela Jörg, Lauren T. May, Peter J. Scammells
Publikováno v:
Journal of Medicinal Chemistry. 65:9076-9095
Autor:
Anh T. N. Nguyen, Diep T. N. Nguyen, Huan Yee Koh, Jason Toskov, William MacLean, Andrew Xu, Daokun Zhang, Geoffrey I. Webb, Lauren T. May, Michelle L. Halls
Publikováno v:
British Journal of Pharmacology.
Autor:
Jo‐Anne Baltos, Pablo M. Casillas‐Espinosa, Ben Rollo, Karen J. Gregory, Paul J. White, Arthur Christopoulos, Patrick Kwan, Terence J. O'Brien, Lauren T. May
Publikováno v:
British Journal of Pharmacology.
Autor:
Bui San Thai, Ling Yeong Chia, Anh T. N. Nguyen, Chengxue Qin, Rebecca H. Ritchie, Dana S. Hutchinson, Andrew Kompa, Paul J. White, Lauren T. May
Publikováno v:
British Journal of Pharmacology.
Autor:
Lauren T. May, Stephen J. Hill, Joel D. A. Tyndall, Daniel J W Chong, Katie Leach, Karen J. Gregory, Phuc N. H. Trinh, Andrea J. Vernall
Publikováno v:
Journal of Medicinal Chemistry. 64:8161-8178
Adenosine receptors are attractive therapeutic targets for multiple conditions, including ischemia-reperfusion injury and neuropathic pain. Adenosine receptor drug discovery efforts would be facilitated by the development of appropriate tools to assi