Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Lauren A. M. Murray"'
Autor:
Lauren A. M. Murray
Publikováno v:
ACS Central Science, Vol 10, Iss 11, Pp 1997-1999 (2024)
Externí odkaz:
https://doaj.org/article/24939d4db63f4b4b9a8a84d9d6975126
Autor:
Percival Yang-Ting Chen, Sanjoy Adak, Jonathan R. Chekan, David K. Liscombe, Akimasa Miyanaga, Peter Bernhardt, Stefan Diethelm, Elisha N. Fielding, Jonathan H. George, Zachary D. Miles, Lauren A. M. Murray, Taylor S. Steele, Jaclyn M. Winter, Joseph P. Noel, Bradley S. Moore
Publikováno v:
Biochemistry. 61:1844-1852
Vanadium-dependent haloperoxidases (VHPOs) from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a765a97e1ef57b6f6534c9d20737639
https://doi.org/10.1021/acs.biochem.2c00338
https://doi.org/10.1021/acs.biochem.2c00338
Publikováno v:
Nat Prod Rep
Covering: Up to January 2020Meroterpenoids derived from the polyketide 1,3,6,8-tetrahydroxynaphthalene (THN) are complex natural products produced exclusively by Streptomyces bacteria. These antibacterial compounds include the napyradiomycins, meroch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e77ae5eaf5cfc611c3b4be438e1d639a
https://doi.org/10.1039/d0np00018c
https://doi.org/10.1039/d0np00018c
Autor:
Stefania A. Sassnink, Quang D. Phan, Hiu C. Lam, Aaron J. Day, Lauren A. M. Murray, Jonathan H. George
Publikováno v:
Organicbiomolecular chemistry. 20(8)
Oxidative degradation and rearrangement of polycyclic polyprenylated acylphloroglucinols (PPAPs) has created diverse families of unique natural products that are attractive targets for biomimetic synthesis. Herein, we report a racemic synthesis of hy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46ac9fae8dbb8438f2aa7cc756856a36
https://pubmed.ncbi.nlm.nih.gov/35166295
https://pubmed.ncbi.nlm.nih.gov/35166295
Autor:
Oussama Yahiaoui, Lauren A. M. Murray, Fengyue Zhao, Bradley S. Moore, Kendall N. Houk, Fang Liu, Jonathan H. George
Publikováno v:
Org Lett
Organic letters, vol 24, iss 2
Organic letters, vol 24, iss 2
Motivated by the biosynthesis of azamerone, we report the first example of a diazo-Hooker reaction, which involves the formation of a phthalazine ring system by the oxidative rearrangement of a diazoketone. Computational studies indicate that the dia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f0a890f10da33bbe79dd9d299848dd1
https://pubmed.ncbi.nlm.nih.gov/34994200
https://pubmed.ncbi.nlm.nih.gov/34994200
Autor:
Lara E. Zetzsche, Jessica A. Yazarians, Suman Chakrabarty, Meagan E. Hinze, Lauren A. M. Murray, April L. Lukowski, Leo A. Joyce, Alison R. H. Narayan
Publikováno v:
Nature
Despite their varied purposes, many indispensable molecules in medicine, materials, and asymmetric catalysis share a biaryl core. The necessity of joining arene building blocks to access these valuable compounds has inspired multiple approaches for b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4209cb376a35410b11e60f2438696057
https://doi.org/10.33774/chemrxiv-2021-v0bv6-v2
https://doi.org/10.33774/chemrxiv-2021-v0bv6-v2
Total Synthesis Establishes the Biosynthetic Pathway to the Naphterpin and Marinone Natural Products
Autor:
Lauren A. M. Murray, Shaun M. K. McKinnie, Henry P. Pepper, Reto Erni, Zachary D. Miles, Michelle C. Cruickshank, Borja López‐Pérez, Bradley S. Moore, Jonathan H. George
Publikováno v:
Angewandte Chemie (International ed. in English), vol 57, iss 34
The naphterpins and marinones are naphthoquinone meroterpenoids with an unusual aromatic oxidation pattern that is biosynthesized from 1,3,6,8-tetrahydroxynaphthalene (THN). We propose that cryptic halogenation of THN derivatives by vanadium-dependen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::453f1a6d1532da8cd4494b80fa7c2a8b
https://doi.org/10.1002/ange.201804351
https://doi.org/10.1002/ange.201804351
Publikováno v:
Organic letters. 21(20)
A concise and divergent strategy for the synthesis of the naphterpin and marinone meroterpenoid families has been developed. The approach features a succession of pericyclic reactions-an aromatic Claisen rearrangement, a retro-6π-electrocyclization,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac7357c91afefd5f27347db8f3009590
https://pubmed.ncbi.nlm.nih.gov/31549845
https://pubmed.ncbi.nlm.nih.gov/31549845
Autor:
Lauren A. M. Murray, Peter A. Jordan, Jonathan H. George, Henry P. Pepper, Takayoshi Awakawa, Shaun M. K. McKinnie, Bradley S. Moore, Zachary D. Miles
Publikováno v:
Journal of the American Chemical Society, vol 140, iss 51
The biosynthetic route to the napyradiomycin family of bacterial meroterpenoids has been fully described 32 years following their original isolation and 11 years after their gene cluster discovery. The antimicrobial and cytotoxic natural products nap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d4928b0c37d0d23b1af83cd7d8fec9c
https://escholarship.org/uc/item/2z25c79p
https://escholarship.org/uc/item/2z25c79p
Total Synthesis Establishes the Biosynthetic Pathway to the Naphterpin and Marinone Natural Products
Autor:
Reto Erni, Bradley S. Moore, Henry P. Pepper, Jonathan H. George, Borja López-Pérez, Michelle C. Cruickshank, Zachary D. Miles, Lauren A. M. Murray, Shaun M. K. McKinnie
Publikováno v:
Angewandte Chemie (International ed. in English). 57(34)
The naphterpins and marinones are naphthoquinone meroterpenoids with an unusual aromatic oxidation pattern that is biosynthesized from 1,3,6,8-tetrahydroxynaphthalene (THN). We propose that cryptic halogenation of THN derivatives by vanadium-dependen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4da3520a1eb47189b0c63caa3b74c20
https://pubmed.ncbi.nlm.nih.gov/29935040
https://pubmed.ncbi.nlm.nih.gov/29935040