Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Lauren A. Hirao"'
Autor:
Mariana G. Weber, Chara J. Walters-Laird, Amir Kol, Clarissa Santos Rocha, Lauren A. Hirao, Abigail Mende, Bipin Balan, Juan Arredondo, Sonny R. Elizaldi, Smita S. Iyer, Alice F. Tarantal, Satya Dandekar
Publikováno v:
JCI Insight, Vol 6, Iss 12 (2021)
Although antiretroviral therapy suppresses HIV replication, it does not eliminate viral reservoirs or restore damaged lymphoid tissue, posing obstacles to HIV eradication. Using the SIV model of AIDS, we investigated the effect of mesenchymal stem/st
Externí odkaz:
https://doaj.org/article/fdc47e612abd4a63ad367e19dd9c43e7
Autor:
Guochun Jiang, Clarissa Santos Rocha, Lauren A. Hirao, Erica A. Mendes, Yuyang Tang, George R. Thompson, Joseph K. Wong, Satya Dandekar
Publikováno v:
mBio, Vol 8, Iss 3 (2017)
ABSTRACT Antiviral innate host defenses against acute viral infections include suppression of host protein synthesis to restrict viral protein production. Less is known about mechanisms by which viral pathogens subvert host antiviral innate responses
Externí odkaz:
https://doaj.org/article/5f18daab70f24fe68dce93e13b2a1b7b
Autor:
Larissa A. Singletary, Joyce E. Karlinsey, Stephen J. Libby, Jason P. Mooney, Kristen L. Lokken, Renée M. Tsolis, Mariana X. Byndloss, Lauren A. Hirao, Christopher A. Gaulke, Robert W. Crawford, Satya Dandekar, Robert A. Kingsley, Chisomo L. Msefula, Robert S. Heyderman, Ferric C. Fang
Publikováno v:
mBio, Vol 7, Iss 2 (2016)
ABSTRACT Nontyphoidal Salmonella enterica serovar Typhimurium is a frequent cause of bloodstream infections in children and HIV-infected adults in sub-Saharan Africa. Most isolates from African patients with bacteremia belong to a single sequence typ
Externí odkaz:
https://doaj.org/article/18c0318f4ce24989a9672270a4aff640
Autor:
Smita S. Iyer, Chara J. Walters-Laird, Amir Kol, Mariana G. Weber, Lauren A. Hirao, Bipin Balan, Alice F. Tarantal, Sonny R. Elizaldi, Clarissa Santos Rocha, Juan Arredondo, Satya Dandekar, Abigail Mende
Publikováno v:
JCI Insight
Although antiretroviral therapy suppresses HIV replication, it does not eliminate viral reservoirs or restore damaged lymphoid tissue, posing obstacles to HIV eradication. Using the SIV model of AIDS, we investigated the effect of mesenchymal stem/st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67806733efff66ffc1ee0e6605f19cf5
https://pubmed.ncbi.nlm.nih.gov/34014838
https://pubmed.ncbi.nlm.nih.gov/34014838
Autor:
Lauren H Nagy, Irina Grishina, Monica Macal, Lauren A Hirao, William K Hu, Sumathi Sankaran-Walters, Christopher A Gaulke, Richard Pollard, Jennifer Brown, Maria Suni, Andreas J Baumler, Smita Ghanekar, Maria L Marco, Satya Dandekar
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e72789 (2013)
Chronic immune activation despite long-term therapy poses an obstacle to immune recovery in HIV infection. The role of antigen presenting cells (APCs) in chronic immune activation during HIV infection remains to be fully determined. APCs, the frontli
Externí odkaz:
https://doaj.org/article/e0fd5ff4dd024cd1b38db40224385ca2
Autor:
Cecilia R Giulivi, Lauren A. Hirao, Christopher A. Gaulke, Katti R. Crakes, Maria L. Marco, Sandipan Datta, Anne Fenton, Sumathi Sankaran-Walters, Irina Grishina, Clarissa Santos Rocha, Eleonora Napoli, Gino A Cortopassi, Juan Arredondo, Satya Dandekar
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 116, iss 49
The FASEB Journal, vol 34, iss S1
Proceedings of the National Academy of Sciences of the United States of America
The FASEB Journal, vol 34, iss S1
Proceedings of the National Academy of Sciences of the United States of America
Significance Our study has identified that impaired peroxisome proliferator-activated receptor-α (PPARα) signaling and associated mitochondrial dysfunction is an important underlying mechanism for prolonged leaky gut barriers in HIV and Simian immu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6ddc43e0a7db32c9193313983e4eee9
https://escholarship.org/uc/item/8gx1n2ng
https://escholarship.org/uc/item/8gx1n2ng
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24250 (2011)
Costimulatory molecules play a central role in the development of cellular immunity. Understanding how costimulatory pathways can be directed to positively influence the immune response may be critical for the generation of an effective HIV vaccine.
Externí odkaz:
https://doaj.org/article/77d1fcd4df1a4d00949221dd3f4bd163
Autor:
Jesse D. Deere, Mariana G. Weber, W. L. William Chang, Ellen E. Sparger, Lauren A. Hirao, Jeffrey A. Roberts, Peter A. Barry, Clarissa Santos Rocha, Gema Méndez-Lagares, Guochun Jiang, Dennis J. Hartigan-O'Connor, Satya Dandekar
Publikováno v:
Journal of virology, vol 92, iss 13
Subclinical viral infections (SVI), including cytomegalovirus (CMV), are highly prevalent in humans, resulting in lifelong persistence. However, the impact of SVI on the interplay between the host immunity and gut microbiota in the context of environ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea9437b8478ea80e4092e5997b9576e2
https://europepmc.org/articles/PMC6002712/
https://europepmc.org/articles/PMC6002712/
Publikováno v:
Golomb, BL; Hirao, LA; Dandekar, S; & Marco, ML. (2016). Gene expression of Lactobacillus plantarum and the commensal microbiota in the ileum of healthy and early SIV-infected rhesus macaques. Scientific Reports, 6. doi: 10.1038/srep24723. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/4d19g02c
Scientific reports, vol 6, iss 1
Scientific Reports
Scientific reports, vol 6, iss 1
Scientific Reports
Chronic HIV infection results in impairment of gut-associated lymphoid tissue leading to systemic immune activation. We previously showed that in early SIV-infected rhesus macaques intestinal dysfunction is initiated with the induction of the IL-1β
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80d80eeed28727a9a099becfa7bff29c
http://www.escholarship.org/uc/item/4d19g02c
http://www.escholarship.org/uc/item/4d19g02c
Autor:
Renée M. Tsolis, Robert S. Heyderman, Chisomo L. Msefula, Kristen L. Lokken, Robert W. Crawford, Joyce E. Karlinsey, Robert A. Kingsley, Ferric C. Fang, Satya Dandekar, Jason P. Mooney, Stephen J. Libby, Lauren A. Hirao, Mariana X. Byndloss, Larissa A. Singletary, Christopher A. Gaulke
Publikováno v:
mBio
mBio, Vol 7, Iss 2, p e02265-15 (2016)
mBio, vol 7, iss 2
mBio, Vol 7, Iss 2 (2016)
Singletary, LA; Karlinsey, JE; Libby, SJ; Mooney, JP; Lokken, KL; Tsolis, RM; et al.(2016). Loss of multicellular behavior in epidemic african nontyphoidal salmonella enterica serovar typhimurium ST313 strain D23580. mBio, 7(2). doi: 10.1128/mBio.02265-15. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/1079t34c
mBio, Vol 7, Iss 2, p e02265-15 (2016)
mBio, vol 7, iss 2
mBio, Vol 7, Iss 2 (2016)
Singletary, LA; Karlinsey, JE; Libby, SJ; Mooney, JP; Lokken, KL; Tsolis, RM; et al.(2016). Loss of multicellular behavior in epidemic african nontyphoidal salmonella enterica serovar typhimurium ST313 strain D23580. mBio, 7(2). doi: 10.1128/mBio.02265-15. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/1079t34c
Nontyphoidal Salmonella enterica serovar Typhimurium is a frequent cause of bloodstream infections in children and HIV-infected adults in sub-Saharan Africa. Most isolates from African patients with bacteremia belong to a single sequence type, ST313,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::548f185885bf5897d99be58ce871643a
http://europepmc.org/articles/PMC4810497
http://europepmc.org/articles/PMC4810497