Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Lauren A. Gay"'
Publikováno v:
Viruses, Vol 14, Iss 10, p 2083 (2022)
Kaposi’s sarcoma-associated herpesvirus (KSHV) is an oncogenic gammaherpesvirus that is the causative agent of primary effusion lymphoma and Kaposi’s sarcoma. In healthy carriers, KSHV remains latent, but a compromised immune system can lead to l
Externí odkaz:
https://doaj.org/article/0108c7315df14428a554e0a6343207bb
Autor:
Karlie Plaisance-Bonstaff, Hong Seok Choi, Tyler Beals, Brian J. Krueger, Isaac W. Boss, Lauren A. Gay, Irina Haecker, Jianhong Hu, Rolf Renne
Publikováno v:
Viruses, Vol 6, Iss 10, Pp 4005-4023 (2014)
Kaposi’s sarcoma-associated herpesvirus (KSHV) microRNAs are encoded in the latency-associated region. Knockdown of KSHV miR-K12-3 and miR-K12-11 increased expression of lytic genes in BC-3 cells, and increased virus production from latently infect
Externí odkaz:
https://doaj.org/article/bdf30603e7324e6a8a1bfcf00d80b9f7
Publikováno v:
Non-Coding RNA, Vol 4, Iss 4, p 31 (2018)
Numerous cellular processes are regulated by microRNAs (miRNAs), both cellular and viral. Elucidating the targets of miRNAs has become an active area of research. An important method in this field is cross-linking and immunoprecipitation (CLIP), wher
Externí odkaz:
https://doaj.org/article/ea6a380aee794c7ebd589730762ab038
Autor:
Irina Haecker, Lauren A. Gay, Yajie Yang, Jianhong Hu, Alison M. Morse, Lauren M. McIntyre, Rolf Renne
Publikováno v:
PLoS Pathogens, Vol 9, Iss 3 (2013)
Externí odkaz:
https://doaj.org/article/d833af9945cb4e639e9a12a53c8e8ec4
Publikováno v:
Curr Protoc
This protocol was designed to identify microRNA (miRNA) targetomes from smaller-input samples by performing a simplified workflow of the Cross-Linking and Sequencing of Hybrids (CLASH) technique developed in the Tollervey group. In this ribonomics-ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e56e36167b6f5d468534ab1c8873dc8
https://pubmed.ncbi.nlm.nih.gov/34610213
https://pubmed.ncbi.nlm.nih.gov/34610213
Autor:
Ines Kozar, Demetra Philippidou, Christiane Margue, Lauren A. Gay, Rolf Renne, Stephanie Kreis
Publikováno v:
Cancers
Volume 13
Issue 5
Cancers, Vol 13, Iss 1096, p 1096 (2021)
Volume 13
Issue 5
Cancers, Vol 13, Iss 1096, p 1096 (2021)
Simple Summary miRNAs are omnipresent short non-coding RNA molecules, which post-transcriptionally fine-tune the expression of most protein-coding genes in health and disease. In cancer, miRNAs have been described to directly regulate the amounts of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20e344590b3bb35fab05457753b9937d
Autor:
Stephan C. Jahn, Lauren A. Gay, Claire J. Weaver, Rolf Renne, Taimour Y. Langaee, Peter W. Stacpoole, Margaret O. James
Publikováno v:
Drug Metab Dispos
Previous work has shown that hepatic levels of human glutathione transferase zeta 1 (GSTZ1) protein, involved in tyrosine catabolism and responsible for metabolism of the investigational drug dichloroacetate, increase in cytosol after birth before re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b28d1e5b58bd944cd6a16048638f11b
https://europepmc.org/articles/PMC7289049/
https://europepmc.org/articles/PMC7289049/
Autor:
Whitney L. Bullard, Mehmet Kara, Lauren A. Gay, Sunantha Sethuraman, Yiping Wang, Shreya Nirmalan, Alim Esemenli, April Feswick, Brett A. Hoffman, Rolf Renne, Scott A. Tibbetts
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 15, Iss 8, p e1007843 (2019)
PLoS Pathogens, Vol 15, Iss 8, p e1007843 (2019)
Gammaherpesviruses, including the human pathogens Epstein-Barr virus (EBV) and Kaposi’s sarcoma-associated herpesvirus (KSHV), establish lifelong latent infection in B cells and are associated with a variety of tumors. In addition to protein coding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15371fad5883158b9d932eddb40b5385
https://pubmed.ncbi.nlm.nih.gov/31393953
https://pubmed.ncbi.nlm.nih.gov/31393953
Publikováno v:
Nucleic acids research. 46(16)
Ribonomics experiments involving crosslinking and immuno-precipitation (CLIP) of Ago proteins have expanded the understanding of the miRNA targetome of several organisms. These techniques, collectively referred to as CLIP-seq, have been applied to id
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ccfd68a49e1b6353009d0e36c40bf16
https://pubmed.ncbi.nlm.nih.gov/29846699
https://pubmed.ncbi.nlm.nih.gov/29846699
Publikováno v:
Journal of virology. 92(8)
Kaposi's sarcoma (KS) tumors are derived from endothelial cells and express Kaposi's sarcoma-associated herpesvirus (KSHV) microRNAs (miRNAs). Although miRNA targets have been identified in B cell lymphoma-derived cells and epithelial cells, little h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5a603427fbf7c1a471034f900bce1d5
https://pubmed.ncbi.nlm.nih.gov/29386283
https://pubmed.ncbi.nlm.nih.gov/29386283