Zobrazeno 1 - 10
of 247
pro vyhledávání: '"Lauren A Weiss"'
Autor:
Mikhail Vysotskiy, Autism Working Group of the Psychiatric Genomics Consortium, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Lauren A Weiss
Publikováno v:
PLoS Genetics, Vol 19, Iss 6, p e1010780 (2023)
The 16p11.2 and 22q11.2 copy number variants (CNVs) are associated with neurobehavioral traits including autism spectrum disorder (ASD), schizophrenia, bipolar disorder, obesity, and intellectual disability. Identifying specific genes contributing to
Externí odkaz:
https://doaj.org/article/5bf2aae80bfa4f8db9463302c23d4b14
Publikováno v:
PLoS Genetics, Vol 18, Iss 5, p e1010147 (2022)
Phenotypic differences across sexes are pervasive, but the genetic architecture of sex differences within and across phenotypes is mostly unknown. In this study, we aimed to improve detection power for sex-differentially contributing SNPs previously
Externí odkaz:
https://doaj.org/article/3fd523dd6dfa4adf86424a9fb9e1d876
Autor:
Ileena Mitra, Kathryn Tsang, Christine Ladd-Acosta, Lisa A Croen, Kimberly A Aldinger, Robert L Hendren, Michela Traglia, Alinoë Lavillaureix, Noah Zaitlen, Michael C Oldham, Pat Levitt, Stanley Nelson, David G Amaral, Irva Hertz-Picciotto, M Daniele Fallin, Lauren A Weiss
Publikováno v:
PLoS Genetics, Vol 13, Iss 6, p e1006831 (2017)
[This corrects the article DOI: 10.1371/journal.pgen.1006425.].
Externí odkaz:
https://doaj.org/article/9daeef46b0aa40d394512c49c17b634a
Autor:
Ileena Mitra, Alinoë Lavillaureix, Erika Yeh, Michela Traglia, Kathryn Tsang, Carrie E Bearden, Katherine A Rauen, Lauren A Weiss
Publikováno v:
PLoS Genetics, Vol 13, Iss 1, p e1006516 (2017)
Although gene-gene interaction, or epistasis, plays a large role in complex traits in model organisms, genome-wide by genome-wide searches for two-way interaction have limited power in human studies. We thus used knowledge of a biological pathway in
Externí odkaz:
https://doaj.org/article/244323ab57a34b9ba5dd3e237151395a
Autor:
Ileena Mitra, Kathryn Tsang, Christine Ladd-Acosta, Lisa A Croen, Kimberly A Aldinger, Robert L Hendren, Michela Traglia, Alinoë Lavillaureix, Noah Zaitlen, Michael C Oldham, Pat Levitt, Stanley Nelson, David G Amaral, Irva Hertz-Picciotto, M Daniele Fallin, Lauren A Weiss
Publikováno v:
PLoS Genetics, Vol 12, Iss 11, p e1006425 (2016)
Sexual dimorphism in common disease is pervasive, including a dramatic male preponderance in autism spectrum disorders (ASDs). Potential genetic explanations include a liability threshold model requiring increased polymorphism risk in females, sex-li
Externí odkaz:
https://doaj.org/article/5c02bf462f364187ba0f2c61578f8f6e
Autor:
Kathryn M Tsang, Lisa A Croen, Anthony R Torres, Martin Kharrazi, Gerald N Delorenze, Gayle C Windham, Cathleen K Yoshida, Ousseny Zerbo, Lauren A Weiss
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76978 (2013)
Effects of parental genotype or parent-offspring genetic interaction are well established in model organisms for a variety of traits. However, these transgenerational genetic models are rarely studied in humans. We have utilized an autism case-contro
Externí odkaz:
https://doaj.org/article/1c2704052cb647939f5ff9f931befebc
Autor:
Casey L. Brinkman, Alex S. Polanski, Daniel Huber, Lauren M. Weiss, Diana Valencia, Mykhaylo Plotnykov
Publikováno v:
The Astronomical Journal, Vol 168, Iss 6, p 281 (2024)
Planets and the stars they orbit are born from the same cloud of gas and dust, and the primordial compositions of rocky exoplanets have been assumed to have iron and refractory abundance ratios consistent with their host star. To test this assumption
Externí odkaz:
https://doaj.org/article/7f6efed2986840ae9ffc6162650f1f8d
Autor:
Mikhail Vysotskiy, Xue Zhong, Tyne W. Miller-Fleming, Dan Zhou, Autism Working Group of the Psychiatric Genomics Consortium^, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium^, Schizophrenia Working Group of the Psychiatric Genomics Consortium^, Nancy J. Cox, Lauren A. Weiss
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-26 (2021)
Abstract Background Deletions and duplications of the multigenic 16p11.2 and 22q11.2 copy number variant (CNV) regions are associated with brain-related disorders including schizophrenia, intellectual disability, obesity, bipolar disorder, and autism
Externí odkaz:
https://doaj.org/article/2695a47cf7bc4fed9c4240fbbe1c7007
Autor:
Kristen Lyall, Jennifer L. Ames, Michelle Pearl, Michela Traglia, Lauren A. Weiss, Gayle C. Windham, Martin Kharrazi, Cathleen K. Yoshida, Robert Yolken, Heather E. Volk, Paul Ashwood, Judy Van de Water, Lisa A. Croen
Publikováno v:
Molecular Autism, Vol 12, Iss 1, Pp 1-23 (2021)
Abstract Background The Early Markers for Autism (EMA) study is a population-based case–control study designed to learn more about early biologic processes involved in ASD. Methods Participants were drawn from Southern California births from 2000 t
Externí odkaz:
https://doaj.org/article/f11d85e56974497aa64f89b713de1da3
Autor:
Alfonso J. Alfini, Junyeon Won, Lauren R. Weiss, Casandra C. Nyhuis, Vadim Zipunnikov, Adam P. Spira, Teresa Liu-Ambrose, Alexander J. Shackman, J. Carson Smith
Publikováno v:
Brain Sciences, Vol 12, Iss 10, p 1360 (2022)
The objective of this study was to understand the associations of sleep and cardiorespiratory fitness with hippocampal volume and global cognition among older adults (n = 30, age = 65.8 years, female = 73.3%). Wrist actigraphy provided objective meas
Externí odkaz:
https://doaj.org/article/2ed0ae10d15a4f069bba4144072f765b