Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Lauren A Kenna"'
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0152662 (2016)
In type 1 diabetes (T1D), β-cell loss is silent during disease progression. Methylation-sensitive quantitative real-time PCR (qPCR) of β-cell-derived DNA in the blood can serve as a biomarker of β-cell death in T1D. Amylin is highly expressed by
Externí odkaz:
https://doaj.org/article/03ee49d3aa814d6d8258aa03677d5235
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e72260 (2013)
β cell pseudoislets (PIs) are used for the in vitro study of β-cells in a three-dimensional (3-D) configuration. Current methods of PI induction require unique culture conditions and extensive mechanical manipulations. Here we report a novel co-cul
Externí odkaz:
https://doaj.org/article/d0b638ae70094e75978c6566ff6778b1
Publikováno v:
Journal of Biological Chemistry. 290:15250-15259
The co-culturing of insulinoma and islet-derived endothelial cell (iEC) lines results in the spontaneous formation of free-floating pseudoislets (PIs). We previously showed that iEC-induced PIs display improved insulin expression and secretion in res
Publikováno v:
Diabetology & Metabolic Syndrome
Background Gestational diabetes mellitus (GDM) affects approximately 7–17 % of all pregnancies and has been recognized as a significant risk factor to neonatal and maternal health. Postpartum, GDM significantly increases the likelihood of developin
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 4, p e0152662 (2016)
PLoS ONE, Vol 11, Iss 4, p e0152662 (2016)
In type 1 diabetes (T1D), β-cell loss is silent during disease progression. Methylation-sensitive quantitative real-time PCR (qPCR) of β-cell-derived DNA in the blood can serve as a biomarker of β-cell death in T1D. Amylin is highly expressed by
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 8, p e72260 (2013)
PLoS ONE, Vol 8, Iss 8, p e72260 (2013)
β cell pseudoislets (PIs) are used for the in vitro study of β-cells in a three-dimensional (3-D) configuration. Current methods of PI induction require unique culture conditions and extensive mechanical manipulations. Here we report a novel co-cul
Autor:
John A. Olsen, Eitan M. Akirav, Michael G. Spelios, Regine C. Tipon, Lauren A. Kenna, Mark M. Stecker
Publikováno v:
EBioMedicine, Vol 10, Iss C, Pp 227-235 (2016)
EBioMedicine
EBioMedicine
Multiple sclerosis (MS) is a neurodegenerative disease of the central nervous system (CNS). Minimally invasive biomarkers of MS are required for disease diagnosis and treatment. Differentially methylated circulating-free DNA (cfDNA) is a useful bioma
Autor:
John A. Olsen, Lauren A. Kenna, Regine C. Tipon, Michael G. Spelios, Mark M. Stecker, Eitan M. Akirav
Publikováno v:
EBioMedicine, Vol 10, Iss C, Pp 227-235 (2016)
Multiple sclerosis (MS) is a neurodegenerative disease of the central nervous system (CNS). Minimally invasive biomarkers of MS are required for disease diagnosis and treatment. Differentially methylated circulating-free DNA (cfDNA) is a useful bioma
Externí odkaz:
https://doaj.org/article/2f52b81ca96c44a088633b9229625d60