Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Laureline Roger"'
Autor:
Laureline Roger, Kelly L. Miners, Louise Leonard, Julia W. Grimstead, David A. Price, Duncan M. Baird, Kristin Ladell
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The fundamental basis of T cell memory remains elusive. It is established that antigen stimulation drives clonal proliferation and differentiation, but the relationship between cellular phenotype, replicative history, and longevity, which is likely e
Externí odkaz:
https://doaj.org/article/9fd079d5624c4d788d97c445966b751e
Autor:
Raya Ahmed, Kelly L. Miners, Julio Lahoz-Beneytez, Rhiannon E. Jones, Laureline Roger, Christina Baboonian, Yan Zhang, Eddie C.Y. Wang, Marc K. Hellerstein, Joseph M. McCune, Duncan M. Baird, David A. Price, Derek C. Macallan, Becca Asquith, Kristin Ladell
Publikováno v:
Cell Reports, Vol 33, Iss 11, Pp 108501- (2020)
Summary: A central paradigm in the field of lymphocyte biology asserts that replicatively senescent memory T cells express the carbohydrate epitope CD57. These cells nonetheless accumulate with age and expand numerically in response to persistent ant
Externí odkaz:
https://doaj.org/article/7885536d2b5e42149b0d76509a9181e5
Autor:
Pedro Costa Del Amo, Julio Lahoz-Beneytez, Lies Boelen, Raya Ahmed, Kelly L Miners, Yan Zhang, Laureline Roger, Rhiannon E Jones, Silvia A Fuertes Marraco, Daniel E Speiser, Duncan M Baird, David A Price, Kristin Ladell, Derek Macallan, Becca Asquith
Publikováno v:
PLoS Biology, Vol 16, Iss 6, p e2005523 (2018)
Adaptive immunity relies on the generation and maintenance of memory T cells to provide protection against repeated antigen exposure. It has been hypothesised that a self-renewing population of T cells, named stem cell-like memory T (TSCM) cells, are
Externí odkaz:
https://doaj.org/article/c85bfaa7e2db4200835697b9df1f03c9
Autor:
Rhiannon E. Jones, Sehyun Oh, Julia W. Grimstead, Jacob Zimbric, Laureline Roger, Nicole H. Heppel, Kevin E. Ashelford, Kate Liddiard, Eric A. Hendrickson, Duncan M. Baird
Publikováno v:
Cell Reports, Vol 8, Iss 4, Pp 1063-1076 (2014)
Short dysfunctional telomeres are capable of fusion, generating dicentric chromosomes and initiating breakage-fusion-bridge cycles. Cells that escape the ensuing cellular crisis exhibit large-scale genomic rearrangements that drive clonal evolution a
Externí odkaz:
https://doaj.org/article/74ca282653444cada7d066278696395b
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e48344 (2012)
Rho GTPases are key regulators of tumour cell invasion and therefore constitute attractive targets for the design of anticancer agents. Several strategies have been developed to modulate their increased activities during cancer progression. Interesti
Externí odkaz:
https://doaj.org/article/4a22ecc5d5f54901a9c638ef4052a19e
Autor:
Ulrika Svenson, Katarina Nordfjäll, Duncan Baird, Laureline Roger, Pia Osterman, Mai-Lis Hellenius, Göran Roos
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e21485 (2011)
There is a considerable heterogeneity in blood cell telomere length (TL) for individuals of similar age and recent studies have revealed that TL changes by time are dependent on TL at baseline. TL is partly inherited, but results from several studies
Externí odkaz:
https://doaj.org/article/0ef5223d771a4663863a8f16c240a732
Autor:
Becca Asquith, Rhiannon E. Jones, Kristin Ladell, Yan Zhang, Julio Lahoz-Beneytez, Laureline Roger, Raya Ahmed, Derek C. Macallan, Edward Chung Yern Wang, Duncan M. Baird, Kelly L. Miners, Joseph M. McCune, Christina Baboonian, Marc K. Hellerstein, David Price
Publikováno v:
Cell Reports
Cell Reports, Elsevier Inc, 2020, 33 (11), pp.108501. ⟨10.1016/j.celrep.2020.108501⟩
Cell Reports, Vol 33, Iss 11, Pp 108501-(2020)
e5
e1
Cell Reports, Elsevier Inc, 2020, 33 (11), pp.108501. ⟨10.1016/j.celrep.2020.108501⟩
Cell Reports, Vol 33, Iss 11, Pp 108501-(2020)
e5
e1
Summary A central paradigm in the field of lymphocyte biology asserts that replicatively senescent memory T cells express the carbohydrate epitope CD57. These cells nonetheless accumulate with age and expand numerically in response to persistent anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::019bd1176b8dcb79c13d493b4d25cfba
https://hal.archives-ouvertes.fr/hal-03204476
https://hal.archives-ouvertes.fr/hal-03204476
Autor:
Julio Lahoz-Beneytez, Kristin Ladell, Duncan M. Baird, Rhiannon E. Jones, Yan Zhang, Lies Boelen, Daniel E. Speiser, Becca Asquith, Laureline Roger, Silvia A. Fuertes Marraco, Kelly L. Miners, David Price, Derek C. Macallan, Raya Ahmed, Pedro Costa del Amo
Publikováno v:
PLoS Biology, Vol 16, Iss 6, p e2005523 (2018)
PLoS Biology
PLoS Biology, Public Library of Science, 2018, 16 (6), pp.e2005523. ⟨10.1371/journal.pbio.2005523⟩
PLoS Biology
PLoS Biology, Public Library of Science, 2018, 16 (6), pp.e2005523. ⟨10.1371/journal.pbio.2005523⟩
Adaptive immunity relies on the generation and maintenance of memory T cells to provide protection against repeated antigen exposure. It has been hypothesised that a self-renewing population of T cells, named stem cell–like memory T (TSCM) cells, a
Autor:
Alison M. Dunning, Veryan Codd, Laureline Roger, Carmen Martin-Ruiz, Duncan M. Baird, Tim De Meyer, Göran Roos, Sofie Bekaert, Martin M Dokter, Petra Boukamp, Ulrika Svenson, Damir Krunic, Andrew Kingston, Thomas von Zglinicki, Pim van der Harst, Rachel Cooper, Andrew Wong, Nilesh J. Samani, Karen A. Pooley, Paul G. Shiels, Richard M. Cawthon, Liane M. McGlynn
Publikováno v:
International Journal of Epidemiology
International Journal of Epidemiology, Oxford University Press (OUP), 2015, 44 (5), pp.1673-1683. ⟨10.1093/ije/dyu191⟩
International Journal of Epidemiology, 44(5), 1673-1683. Oxford University Press
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
International Journal of Epidemiology, Oxford University Press (OUP), 2015, 44 (5), pp.1749-1754. ⟨10.1093/ije/dyv171⟩
International Journal of Epidemiology, 2015, 44 (5), pp.1673-1683. ⟨10.1093/ije/dyu191⟩
International Journal of Epidemiology, 2015, 44 (5), pp.1749-1754. ⟨10.1093/ije/dyv171⟩
International Journal of Epidemiology, Oxford University Press (OUP), 2015, 44 (5), pp.1673-1683. ⟨10.1093/ije/dyu191⟩
International Journal of Epidemiology, 44(5), 1673-1683. Oxford University Press
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
International Journal of Epidemiology, Oxford University Press (OUP), 2015, 44 (5), pp.1749-1754. ⟨10.1093/ije/dyv171⟩
International Journal of Epidemiology, 2015, 44 (5), pp.1673-1683. ⟨10.1093/ije/dyu191⟩
International Journal of Epidemiology, 2015, 44 (5), pp.1749-1754. ⟨10.1093/ije/dyv171⟩
Background: Telomere length is a putative biomarker of ageing, morbidity and mortality. Its application is hampered by lack of widely applicable reference ranges and uncertainty regarding the present limits of measurement reproducibility within and b
Autor:
Duncan M. Baird, Andras Rudolf, Rhiannon E. Jones, Donald James Fraser, Timothy Bowen, Melisa Lopez-Anton, Laureline Roger, Janusz Witowski
Publikováno v:
Mechanisms of Ageing and Development
Mechanisms of Ageing and Development, Elsevier, 2017, 164, pp.37-40. ⟨10.1016/j.mad.2017.03.010⟩
Mechanisms of Ageing and Development, 2017, 164, pp.37-40. ⟨10.1016/j.mad.2017.03.010⟩
Mechanisms of Ageing and Development, Elsevier, 2017, 164, pp.37-40. ⟨10.1016/j.mad.2017.03.010⟩
Mechanisms of Ageing and Development, 2017, 164, pp.37-40. ⟨10.1016/j.mad.2017.03.010⟩
Mesothelial cell (MC) senescence contributes to malignancy and tissue fibrosis. The\ud role of telomere erosion in MC senescence remains controversial, with evidence for\ud both telomere-dependent and telomere-independent mechanisms reported. Single\
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25fe28e03fe9ebb73991380800543f95
https://hal.archives-ouvertes.fr/hal-03204489
https://hal.archives-ouvertes.fr/hal-03204489