Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Laurel T, Tainsh"'
Publikováno v:
Ophthalmology. 130:379-386
Publikováno v:
International Ophthalmology Clinics. 62:145-156
Publikováno v:
Ophthalmology.
Open globe injuries (OGIs) are categorized by zone, with zone 3 (Z3) comprising wounds5 mm beyond the limbus. Outcomes of Z3 OGIs are highly heterogeneous. Open globe injuries with far posterior Z3 (pZ3) wounds were hypothesized to have worse visual
Autor:
Guo Ling Zhou, Arkadi Beloiartsev, Binglan Yu, David M Baron, Weihua Zhou, Rasma Niedra, Naifang Lu, Laurel T Tainsh, Warren M Zapol, Brian Seed, Kenneth D Bloch
Publikováno v:
PLoS Genetics, Vol 9, Iss 11, p e1003950 (2013)
Epoxyeicosatrienoic acids (EETs) confer vasoactive and cardioprotective functions. Genetic analysis of the contributions of these short-lived mediators to pathophysiology has been confounded to date by the allelic expansion in rodents of the portion
Externí odkaz:
https://doaj.org/article/8dc92b3772fe40a68d870e96ab003376
Autor:
Emmanuel S Buys, Yu-Chieh Ko, Clemens Alt, Sarah R Hayton, Alexander Jones, Laurel T Tainsh, Ruiyi Ren, Andrea Giani, Maeva Clerté, Emma Abernathy, Robert E T Tainsh, Dong-Jin Oh, Rajeev Malhotra, Pankaj Arora, Nadine de Waard, Binglan Yu, Raphael Turcotte, Daniel Nathan, Marielle Scherrer-Crosbie, Stephanie J Loomis, Jae H Kang, Charles P Lin, Haiyan Gong, Douglas J Rhee, Peter Brouckaert, Janey L Wiggs, Meredith S Gregory, Louis R Pasquale, Kenneth D Bloch, Bruce R Ksander
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e60156 (2013)
Primary open angle glaucoma (POAG) is a leading cause of blindness worldwide. The molecular signaling involved in the pathogenesis of POAG remains unknown. Here, we report that mice lacking the α1 subunit of the nitric oxide receptor soluble guanyla
Externí odkaz:
https://doaj.org/article/cdb4e77ca1f6419cb61140dd1cfbf975
Publikováno v:
Clinical & Experimental Ophthalmology. 48:134-136
Autor:
Rajeev Malhotra, Emmanuel S. Buys, Kaitlin Allen, Christine Stevens, Ana C. Dordea, Kenneth D. Bloch, Allyson G. Hindle, Sara Vandenwijngaert, Daniel Bloch, Robert E. Tainsh, Michael J. Raher, Michal L. Schwartzman, John R. Falck, Robrecht Thoonen, Daniel I. Nathan, Andrew Kirby, Victor Garcia, Laurel T. Tainsh, Wolfgang S. Lieb, Peter Brouckaert, Mark J. Daly, Sarah Mikelman, Frank Zhang, Patrick Sips
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 310:H1790-H1800
Dysregulated nitric oxide (NO) signaling contributes to the pathogenesis of hypertension, a prevalent and often sex-specific risk factor for cardiovascular disease. We previously reported that mice deficient in the α1-subunit of the NO receptor solu
Autor:
Maryam Ghiassi-Nejad, Laurel T. Tainsh, Lawrence J. Rizzolo, Deepti Singh, Ron A. Adelman, X. Chen, Tina Xia
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose Many studies have demonstrated the ability of the retinal pigment epithelium (RPE) to foster the maturation of the developing retina. Few studies have examined the reciprocal effects of developing retina on the RPE. Methods RPE isolated from
Autor:
Shaomin Peng, Tina Xia, Lawrence J. Rizzolo, Maryam Ghiassi-Nejad, Deepti Singh, Tao Xu, Ron A. Adelman, Laurel T. Tainsh, Shaobin Wang
Publikováno v:
Biomaterials. 154
Retinal degeneration is a leading cause of blindness in developed countries. Stem cells can be differentiated into retinal organoids to study mechanisms of retinal degeneration, develop therapeutic agents, and potentially serve as replacement tissues
Autor:
Seth W. Meskin, Jessica Chow, John H. Sinard, Natalia Neparidze, Patrick A. Coady, Ron A. Adelman, Laurel T. Tainsh
Publikováno v:
Cornea. 36(3)
Purpose To report a case of asymmetric deep stromal keratopathy in a patient with multiple myeloma. Methods Case report and literature review. Results An 85-year-old woman was found to have progressive visually significant left-sided deep stromal opa