Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Laurel L. Ballantyne"'
Autor:
Laura A. McKiel, Laurel L. Ballantyne, Gian Luca Negri, Kimberly A. Woodhouse, Lindsay E. Fitzpatrick
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The adsorbed protein layer on an implanted biomaterial surface is known to mediate downstream cell-material interactions that drive the host response. While the adsorption of plasma-derived proteins has been studied extensively, the adsorption of dam
Externí odkaz:
https://doaj.org/article/0cda214abe954b55ad71a591f0b6d017
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Implanted biomaterials elicit an immune-mediated foreign body reaction (FBR) that results in the fibrous encapsulation of the implant and can critically impact the performance of some implants. Consequently, understanding the molecular mechanisms tha
Externí odkaz:
https://doaj.org/article/e5ba769638ce4992bdd599b2d72a8198
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 10, Iss , Pp 122-130 (2018)
Progress in gene editing research has been accelerated by utilizing engineered nucleases in combination with induced pluripotent stem cell (iPSC) technology. Here, we report transcription activator-like effector nuclease (TALEN)-mediated reincorporat
Externí odkaz:
https://doaj.org/article/5c25580fe484488fb2b78edcd83ed99d
Autor:
Xinzhi Li, Liudmila L. Mazaleuskaya, Chong Yuan, Laurel L. Ballantyne, Hu Meng, William L. Smith, Garret A. FitzGerald, Colin D. Funk
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 1, Pp 89-101 (2018)
Two prostaglandin (PG) H synthases encoded by Ptgs genes, colloquially known as cyclooxygenase (COX)-1 and COX-2, catalyze the formation of PG endoperoxide H2, the precursor of the major prostanoids. To address the functional interchangeability of th
Externí odkaz:
https://doaj.org/article/4450a3c1881d499a884a360424200b75
Autor:
Xinzhi Li, Liudmila L. Mazaleuskaya, Laurel L. Ballantyne, Hu Meng, Garret A. FitzGerald, Colin D. Funk
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 1, Pp 102-112 (2018)
Both cyclooxygenase (COX)-1 and COX-2, encoded by Ptgs1 and Ptgs2, function coordinately during inflammation. But the relative contributions and compensations of COX-1 and COX-2 to inflammatory responses remain unanswered. We used three engineered mo
Externí odkaz:
https://doaj.org/article/8f52a30ace1d45f2ac18c73e847ab6e1
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Arginase-1 deficiency in humans is a rare genetic disorder of metabolism resulting from a loss of arginase-1, leading to impaired ureagenesis, hyperargininemia and neurological deficits. Previously, we generated a tamoxifen-inducible arginas
Externí odkaz:
https://doaj.org/article/eae6a3ed458b46789cceae268bf9e7a9
Autor:
Xinzhi Li, Liudmila L. Mazaleuskaya, Chong Yuan, Laurel L. Ballantyne, Hu Meng, William L. Smith, Garret A. FitzGerald, Colin D. Funk
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 10, Pp 2035- (2018)
Externí odkaz:
https://doaj.org/article/bb135825914d43f09fb7f17021c72624
Publikováno v:
FASEB J
Adipose tissue–secreted extracellular vesicles (EVs) containing microRNAs (miRNAs) convey intercellular message signaling. The biogenesis of EV-miRNAs from perivascular adipose tissue (PVAT) and their roles in intercellular communication in respons
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Scientific Reports
Scientific Reports
The participation of cyclooxygenase (COX) in embryo implantation and parturition has been studied extensively. However, the distinct role of the two COX isoforms in these processes still remains unclear. Using three characterized mouse lines where th
Publikováno v:
Molecular Therapy. Nucleic Acids
Molecular Therapy: Nucleic Acids, Vol 10, Iss, Pp 122-130 (2018)
Molecular Therapy: Nucleic Acids, Vol 10, Iss, Pp 122-130 (2018)
Progress in gene editing research has been accelerated by utilizing engineered nucleases in combination with induced pluripotent stem cell (iPSC) technology. Here, we report transcription activator-like effector nuclease (TALEN)-mediated reincorporat