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pro vyhledávání: '"Laurel Coons"'
Autor:
Camille Allard, Fabrice Bonnet, Beibei Xu, Laurel Coons, Diana Albarado, Cristal Hill, Guy Fagherazzi, Kenneth S. Korach, Ellis R. Levin, John Lefante, Christopher Morrison, Franck Mauvais-Jarvis
Publikováno v:
Molecular Metabolism, Vol 22, Iss , Pp 62-70 (2019)
Objective: The endogenous estrogen 17β-estradiol (E2) promotes metabolic homeostasis in premenopausal women. In a mouse model of post-menopausal metabolic syndrome, we reported that estrogens increased energy expenditure, thus preventing estrogen de
Externí odkaz:
https://doaj.org/article/22845b7e6aaf4aaca4ff19e56c09711d
Autor:
Kenneth S. Korach, Laurel Coons
Publikováno v:
IUPHAR/BPS Guide to Pharmacology CITE. 2023
Estrogen receptor (ER) activity regulates diverse physiological processes via transcriptional modulation of target genes [2]. The selection of target genes and the magnitude of the response, be it induction or repression, are determined by many facto
Autor:
Janet E. Hall, Lynn P. Chorich, Soumia Brakta, Kenneth Korach, Lawrence C. Layman, Laurel Coons, Hyung Goo Kim
Publikováno v:
Journal of the Endocrine Society
We previously reported the first female with a mutation in the ESR1 gene encoding estrogen receptor-α (ER-α), which dramatically reduced estrogen signaling in vitro. She presented at 179/12 years with absent breast development, markedly elevated se