Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Laurel B. Kartchner"'
Autor:
Lauren Radlinski, Sarah E Rowe, Laurel B Kartchner, Robert Maile, Bruce A Cairns, Nicholas P Vitko, Cindy J Gode, Anne M Lachiewicz, Matthew C Wolfgang, Brian P Conlon
Publikováno v:
PLoS Biology, Vol 15, Iss 11, p e2003981 (2017)
Chronic coinfections of Staphylococcus aureus and Pseudomonas aeruginosa frequently fail to respond to antibiotic treatment, leading to significant patient morbidity and mortality. Currently, the impact of interspecies interaction on S. aureus antibi
Externí odkaz:
https://doaj.org/article/d8adf3a2ad8f4e649b1aae0fce4a225a
Autor:
Julia L.M. Dunn, Matthew C. Wolfgang, Bruce A. Cairns, Lindsey I. Glenn, Danté N. Duncan, Robert Maile, Laurel B. Kartchner, Cindy J. Gode
Publikováno v:
Burns
Objective Burn injury induces an acute hyperactive immune response followed by a chronic immune dysregulation that leaves those afflicted susceptible to multiple secondary infections. Many murine models are able to recapitulate the acute immune respo
Autor:
Crystal J Neely, Laurel B Kartchner, April E Mendoza, Brandon M Linz, Jeffrey A Frelinger, Matthew C Wolfgang, Robert Maile, Bruce A Cairns
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85623 (2014)
Severe trauma renders patients susceptible to infection. In sepsis, defective bacterial clearance has been linked to specific deviations in the innate immune response. We hypothesized that innate immune modulations observed during sepsis also contrib
Externí odkaz:
https://doaj.org/article/58df9bae9cfd44628d98b581b83d1319
Autor:
Rebecca A. Hunter, Marci R. Sessions, Anthony R. Richardson, Bruce A. Cairns, Mark H. Schoenfisch, Lance R. Thurlow, Karli Gast, Laurel B. Kartchner, Julia L.M. Dunn, Robert Maile
Publikováno v:
Journal of Leukocyte Biology. 103:909-918
Bacterial pneumonia is a leading cause of death late after burn injury due to the severe immune dysfunction that follows this traumatic injury. The Mechanistic/Mammalian Target of Rapamycin (mTOR) pathway drives many effector functions of innate immu
Autor:
Laurel B. Kartchner, John Mario González, Manu Forero-Shelton, Veronica Akle, María Alejandra Molina-Rodríguez, Nathalie Agudelo-Dueñas, Annette Marie Ruth
Publikováno v:
Journal of Visualized Experiments.
Chagas disease is a parasitic infection caused by Trypanosoma cruzi, whose motility is not only important for localization, but also for cellular binding and invasion. Current animal models for the study of T. cruzi allow limited observation of paras
Autor:
Bruce A. Cairns, June Brickey, Agnieszka D. Truax, April E. Mendoza, Jenny P.-Y. Ting, Brandon Linz, Gregory D. Sempowski, Timothy K. Eitas, Crystal J. Neely, Amal L. Khoury, Laurel B. Kartchner, Robert Maile
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 198(6)
With enhanced concerns of terrorist attacks, dual exposure to radiation and thermal combined injury (RCI) has become a real threat with devastating immunosuppression. NLRP12, a member of the NOD-like receptor family, is expressed in myeloid and bone
Publikováno v:
The Journal of Immunology. 200:114.23-114.23
Smoke inhalation associated with structural fires, wildfires, or explosions leads to lung injury. Clinically relevant animal models are needed to develop therapeutics. We have previously reported that damage associated molecular patterns (DAMPs) and
Autor:
Charlotte A. Lanteri, Char Meng Chuor, Prom Satharath, Sujata Balasubramanian, Nicholas J. Hathaway, Oksana Kharabora, Jonathan J. Juliano, Sabaithip Sriwichai, Chanthap Lon, Laurel B. Kartchner, Jessica T. Lin, Jeffrey A. Bailey, Panita Gosi, David L. Saunders
Publikováno v:
The Journal of infectious diseases. 212(6)
In recent years, there has been an increased appreciation that global malaria elimination efforts cannot succeed without a better understanding of Plasmodium vivax, the leading cause of malaria outside Africa [1–3]. In particular, P. vivax's abilit
Autor:
Bruce A. Cairns, Matthew C. Wolfgang, Anne M. Lachiewicz, Nicholas P. Vitko, Sarah E. Rowe, Brian P. Conlon, Lauren C. Radlinski, Cindy J. Gode, Laurel B. Kartchner, Robert Maile
Publikováno v:
PLoS Biology
PLoS Biology, Vol 15, Iss 11, p e2003981 (2017)
PLoS Biology, Vol 15, Iss 11, p e2003981 (2017)
Chronic coinfections of Staphylococcus aureus and Pseudomonas aeruginosa frequently fail to respond to antibiotic treatment, leading to significant patient morbidity and mortality. Currently, the impact of interspecies interaction on S. aureus antibi
Publikováno v:
The FASEB Journal. 25