The Vaginal Microbiome of Nonhuman Primates Can Be Only Transiently Altered to Become Lactobacillus Dominant without Reducing Inflammation

Autor: Charlotte A. Langner, Alexandra M. Ortiz, Jacob K. Flynn, Heather Kendall, Laurel A. Lagenaur, Jason M. Brenchley

Publikováno v: Microbiology Spectrum, Vol 9, Iss 3 (2021)

ABSTRACT The vaginal microbiome composition in humans is categorized based upon the degree to which one of four species of Lactobacillus is dominant (Lactobacillus crispatus, community state type I [CST I], Lactobacillus gasseri, CST II, Lactobacillu

Externí odkaz: https://doaj.org/article/c233818a83a24dceb9fa3787b6f8913c

A Summary of the Fifth Annual Virology Education HIV Microbiome Workshop

Autor: Scott Sherrill-Mix, Gilda Tachedjian, Ronald G. Collman, Jim A. Turpin, Laurel A. Lagenaur, Frederic D. Bushman, Nichole R. Klatt, Alan L. Landay, Roger Paredes, Grace M. Aldrovandi, Kaleigh Connors, Mimi Ghosh, Jason M. Brenchley, Satya Dandekar, Charles A. Boucher

Publikováno v: AIDS Res Hum Retroviruses
AIDS research and human retroviruses, vol 36, iss 11
AIDS Research and Human Retroviruses, 36(11), 886-895. Mary Ann Liebert Inc.

Each year, a growing international collection of researchers meets at the NIH to share and discuss developments in the microbiome HIV story. This past year has seen continued progress toward a detailed understanding of host-microbe interactions both

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31fbf82044646f5fa377c5f14eff377b
https://doi.org/10.1089/aid.2020.0121

Protection against SARS-CoV-2 infection by a mucosal vaccine in rhesus macaques

Autor: Roushu Zhang, Jason Velasco, Lai-Xi Wang, Jack Greenhouse, Laurent Pessaint, Kevin W. Bock, Bianca M. Nagata, Mahnaz Minai, Renita Brown, Jay A. Berzofsky, Yongjun Sui, Tammy Putman-Taylor, Hanne Leth Andersen, Mark G. Lewis, Jianping Li, David Venzon, Laurel A. Lagenaur, Ian N. Moore, Elyse Teow, Sunaina Kiran Prabhu, Matthew Breed, Josh Kramer, Jim Talton, Tracey-Ann Campbell, Anthony L. Cook

Publikováno v: JCI Insight

Effective SARS-CoV-2 vaccines are urgently needed. Although most vaccine strategies have focused on systemic immunization, here we compared the protective efficacy of 2 adjuvanted subunit vaccines with spike protein S1: an intramuscularly primed/boos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4d4c707e5e5482f8f4eafe03d127ecf
http://europepmc.org/articles/PMC8262352

Stool antigen immunodetection for diagnosis of Giardia duodenalis infection in human subjects with HIV and cancer

Autor: Shahram Solaymani-Mohammadi, Iraj Sharifi, Martin F. Kagnoff, H Kamyabi, Laurel A. Lagenaur, Behjat Kalantari-Khandani, Maryam Nooshadokht, Steven M. Singer, Namal P.M. Liyanage, Zahra Babaei

Publikováno v: Journal of Microbiological Methods. 141:35-41

Human infection with the protozoan parasite Giardia duodenalis is one the most common parasitic diseases worldwide. Higher incidence rates of giardiasis have been reported from human subjects with multiple debilitating chronic conditions, including h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57c9c779436a1ae8c142a6739c3659ef
https://doi.org/10.1016/j.mimet.2017.07.004

Protein-Based HIV-1 Microbicides

Autor: Paolo Lusso, Barna Dey, Laurel A. Lagenaur

Publikováno v: Current HIV Research. 11:576-594

Although the development of a protective vaccine remains the most effective strategy for the global control of HIV/AIDS, another practical form of medical intervention would be a microbicide capable of preventing HIV-1 transmission at the mucosal lev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aa93258ed96f5c746937ea7f7a077f1
https://doi.org/10.2174/1570162x11666140101120709