Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Laurel A, Grisanti"'
Autor:
Santosh R. Alluri, Yusuke Higashi, Ashley Berendzen, Laurel A. Grisanti, Lisa D. Watkinson, Kamlendra Singh, Timothy J. Hoffman, Terry Carmack, Elizabeth A. Devanny, Miles Tanner, Kun-Eek Kil
Publikováno v:
EJNMMI Research, Vol 13, Iss 1, Pp 1-17 (2023)
Abstract Background CXCR3 is a chemokine receptor and is expressed in innate and adaptive immune cells. It promotes the recruitment of T-lymphocytes and other immune cells to the inflammatory site in response to the binding of cognate chemokines. Upr
Externí odkaz:
https://doaj.org/article/73c5c4708f6f4cbca64b73a63ab736cb
Autor:
Laurel A. Grisanti
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Cardiovascular disease is a leading cause of death worldwide. Loss of cardiomyocytes that occurs during many types of damage to the heart such as ischemic injury and stress caused by pressure overload, diminishes cardiac function due to their limited
Externí odkaz:
https://doaj.org/article/0c205863d22e4394ab94168d85cb5c6d
Autor:
Miles A. Tanner, Laurel A. Grisanti
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
The fibrotic response is involved in nearly all forms of heart failure and dysregulated responses can lead to enhanced cardiac dysfunction. TNF-related apoptosis-inducing ligand (TRAIL) and its receptor, death receptor (DR) 5, are associated with mul
Externí odkaz:
https://doaj.org/article/7bb8df517f63447ea077e106bac97485
Autor:
Toby P. Thomas, Laurel A. Grisanti
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Heart failure is a leading cause of death worldwide. While there are multiple etiologies contributing to the development of heart failure, all cause result in impairments in cardiac function that is characterized by changes in cardiac remodeling and
Externí odkaz:
https://doaj.org/article/de0481e867e649dfb51dd268f18dbf86
Autor:
Laurel A. Grisanti
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
The prevalence of diabetes is rapidly increasing and closely associated with cardiovascular morbidity and mortality. While the major cardiovascular complication associated with diabetes is coronary artery disease, it is becoming increasingly apparent
Externí odkaz:
https://doaj.org/article/6a38fba27f8b4278b1e8e0608c5bfadd
Autor:
Malathi S. I. Dona, Ian Hsu, Alex I. Meuth, Scott M. Brown, Chastidy A. Bailey, Christian G. Aragonez, Jacob J. Russell, Crisdion Krstevski, Annayya R. Aroor, Bysani Chandrasekar, Luis A. Martinez-Lemus, Vincent G. DeMarco, Laurel A. Grisanti, Iris Z. Jaffe, Alexander R. Pinto, Shawn B. Bender
Publikováno v:
Basic Research in Cardiology. 118
Coronary microvascular dysfunction (CMD) is associated with cardiac dysfunction and predictive of cardiac mortality in obesity, especially in females. Clinical data further support that CMD associates with development of heart failure with preserved
Autor:
Laurel A, Grisanti
Publikováno v:
Current Protocols. 3
β-adrenergic receptors regulate cardiac function in both the healthy and failing heart. Their expression is decreased in heart failure due to chronic overactivation of the sympathetic nervous system, contributing to declines in cardiac function and
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 22, p 8507 (2020)
Fibroblasts are an important resident cell population in the heart involved in maintaining homeostasis and structure during normal conditions. They are also crucial in disease states for sensing signals and initiating the appropriate repair responses
Externí odkaz:
https://doaj.org/article/44c5d767811e4ee2b4693d9ffb6634ac
Autor:
Malathi S. I. Dona, Ian Hsu, Alex I. Meuth, Scott M. Brown, Chastidy Bailey, Christian G. Aragonez, Bysani Chandrasekar, Luis A. Martinez-Lemus, Vincent G. DeMarco, Laurel A. Grisanti, Iris Z. Jaffe, Alexander R. Pinto, Shawn B. Bender
Coronary microvascular dysfunction (CMD) is associated with cardiac dysfunction and predictive of cardiac mortality in obesity, especially in females. Emerging evidence suggests development of heart failure with preserved ejection fraction in females
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc0cf40f095df20625bf76d10eeee48c
https://doi.org/10.1101/2022.03.24.485542
https://doi.org/10.1101/2022.03.24.485542
Autor:
Santosh Alluri, Seth M. Eisenberg, Laurel A. Grisanti, Miles Tanner, Nora D. Volkow, Sung Won Kim, Kun-Eek Kil
Publikováno v:
European Journal of Medicinal Chemistry. 243:114764
As one of the nine subtypes of adrenergic receptors (ARs) in the brain, α2C-ARs play essential roles in emotion and memory, and are implicated in neuropsychiatric disorders, including depression, Alzheimer's disease, substance use disorder, and schi