Identification of oncolytic vaccinia restriction factors in canine high-grade mammary tumor cells using single-cell transcriptomics.

Autor: Béatrice Cambien, Kevin Lebrigand, Alberto Baeri, Nicolas Nottet, Catherine Compin, Audrey Lamit, Olivier Ferraris, Christophe N Peyrefitte, Virginie Magnone, Jérôme Henriques, Laure-Emmanuelle Zaragosi, Sophie Giorgetti-Peraldi, Frédéric Bost, Marine Gautier-Isola, Roger Rezzonico, Pascal Barbry, Robert Barthel, Bernard Mari, Georges Vassaux

Publikováno v: PLoS Pathogens, Vol 16, Iss 10, p e1008660 (2020)

Mammary carcinoma, including triple-negative breast carcinomas (TNBC) are tumor-types for which human and canine pathologies are closely related at the molecular level. The efficacy of an oncolytic vaccinia virus (VV) was compared in low-passage prim

Externí odkaz: https://doaj.org/article/198a1a51898d44c0979a58f01abe50b5

Post-transcriptional gene silencing mediated by microRNAs is controlled by nucleoplasmic Sfpq

Autor: Silvia Bottini, Nedra Hamouda-Tekaya, Raphael Mategot, Laure-Emmanuelle Zaragosi, Stephane Audebert, Sabrina Pisano, Valerie Grandjean, Claire Mauduit, Mohamed Benahmed, Pascal Barbry, Emanuela Repetto, Michele Trabucchi

Publikováno v: Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)

MicroRNAs have been best characterized for their functions in the cytoplasm; however, there is growing evidence of a nuclear localized role. Here, the authors identify Sfpq as an Ago2-interacting protein that modulates miRNA activity in both the nucl

Externí odkaz: https://doaj.org/article/a9569527816747cead945fe23c5ab98f

'Seed-Milarity' confers to hsa-miR-210 and hsa-miR-147b similar functional activity.

Autor: Thomas Bertero, Sébastien Grosso, Karine Robbe-Sermesant, Kevin Lebrigand, Imene-Sarah Hénaoui, Marie-Pierre Puisségur, Sandra Fourre, Laure-Emmanuelle Zaragosi, Nathalie M Mazure, Gilles Ponzio, Bruno Cardinaud, Pascal Barbry, Roger Rezzonico, Bernard Mari

Publikováno v: PLoS ONE, Vol 7, Iss 9, p e44919 (2012)

Specificity of interaction between a microRNA (miRNA) and its targets crucially depends on the seed region located in its 5'-end. It is often implicitly considered that two miRNAs sharing the same biological activity should display similarity beyond

Externí odkaz: https://doaj.org/article/05635574baa644af8921c267ef2aaaf6

An integrated cell atlas of the human lung in health and disease

Autor: Malte Luecken, Lisa Sikkema, Daniel Strobl, Luke Zappia, Elo Madissoon, Nikolay Markov, Laure-Emmanuelle Zaragosi, Meshal Ansari, Marie-Jeanne Arguel, Leonie Apperloo, Christophe Becavin, Marijn Berg, Evgeny Chichelnitskiy, Mei-i Chung, Antoine Collin, Aurore Gay, Baharak Hooshiar Kashani, Manu Jain, Theodore Kapellos, Tessa Kole, Christoph Mayr, Michael von Papen, Lance Peter, Ciro Ramírez-Suástegui, Janine Schniering, Chase Taylor, Thomas Walzthoeni, Chuan Xu, Linh Bui, Carlo de Donno, Leander Dony, Minzhe Guo, Austin Gutierrez, Lukas Heumos, Ni Huang, Ignacio Ibarra Del Río, Nathan Jackson, Preetish Kadur Lakshminarasimha Murthy, Mohammad Lotfollahi, Tracy Tabib, Carlos Talavera-Lopez, Kyle Travaglini, Anna Wilbrey-Clark, Kaylee Worlock, Masahiro Yoshida, Tushar Desai, Orit Rozenblatt-Rosen, Christine Falk, Naftali Kaminski, Mark Krasnow, Robert Lafyatis, Marko Nikolic, Joseph Powell, Jay Rajagopal, Max Seibold, Dean Sheppard, Douglas Shepherd, Sarah Teichmann, Alexander Tsankov, Jeffrey Whitsett, Yan Xu, Nicholas Banovich, Pascal Barbry, Thu Duong, Kerstin Meyer, Jonathan Kropski, Dana Pe'er, Herbert Schiller, Purushothama Rao Tata, Joachim Schultze, Maarten van den Berge, Yuexin Chen, James Hagood, Ahmed Hassan, Peter Horvath, Joakim Lundeberg, Sylvie Leroy, Charles Marquette, Gloria Pryhuber, Christos Samakovlis, Xin Sun, Lorraine Ware, Kun Zhang, Alexander Misharin, Martijn Nawijn, Fabian Theis

Organ- and body-scale cell atlases have the potential to transform our understanding of human biology. To capture the variability present in the population, these atlases must include diverse demographics such as age and ethnicity from both healthy a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6c225b8ec842494e3c796c31c793715c
https://doi.org/10.21203/rs.3.rs-1438584/v1

The discovAIR project

Autor: Malte D. Luecken, Laure-Emmanuelle Zaragosi, Elo Madissoon, Lisa Sikkema, Alexandra B. Firsova, Elena De Domenico, Louis Kümmerle, Adem Saglam, Marijn Berg, Aurore C.A. Gay, Janine Schniering, Christoph H. Mayr, Xesús M. Abalo, Ludvig Larsson, Alexandros Sountoulidis, Sarah A. Teichmann, Karen van Eunen, Gerard H. Koppelman, Kourosh Saeb-Parsy, Sylvie Leroy, Pippa Powell, Ugis Sarkans, Wim Timens, Joakim Lundeberg, Maarten van den Berge, Mats Nilsson, Peter Horváth, Jessica Denning, Irene Papatheodorou, Joachim L. Schultze, Herbert B. Schiller, Pascal Barbry, Ilya Petoukhov, Alexander V. Misharin, Ian M. Adcock, Michael von Papen, Fabian J. Theis, Christos Samakovlis, Kerstin B. Meyer, Martijn C. Nawijn

Publikováno v: European Respiratory Journal
The European respiratory journal 60(2), 2102057 (2022). doi:10.1183/13993003.02057-2021
Eur. Respir. J. 59:2102057 (2022)

The Human Cell Atlas (HCA) consortium aims to establish an atlas of all organs in the healthy human body at single-cell resolution to increase our understanding of basic biological processes that govern development, physiology and anatomy, and to acc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f581433ea51435d26d857eb0a83d27a3
https://hdl.handle.net/11370/eeca5057-97a6-45f7-9dac-92e84b6d1f46