Výsledky vyhledávání - "Laure Tonini"

Akademický článek

Potential Plasticity of the Mannoprotein Repertoire Associated to Mycobacterium tuberculosis Virulence Unveiled by Mass Spectrometry-Based Glycoproteomics

Autor: Laure Tonini, Bashir Sadet, Alexandre Stella, David Bouyssié, Jérôme Nigou, Odile Burlet-Schiltz, Michel Rivière

Publikováno v: Molecules, Vol 25, Iss 10, p 2348 (2020)

To date, Mycobacterium tuberculosis (Mtb) remains the world’s greatest infectious killer. The rise of multidrug-resistant strains stresses the need to identify new therapeutic targets to fight the epidemic. We previously demonstrated that bacterial

Externí odkaz: https://doaj.org/article/4d6e8e062d344af5bfc2a36e355d6650

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Potential Plasticity of the Mannoprotein Repertoire Associated to Mycobacterium tuberculosis Virulence Unveiled by Mass Spectrometry-Based Glycoproteomics

Autor: Jérôme Nigou, Odile Burlet-Schiltz, Alexandre Stella, Laure Tonini, Michel Rivière, David Bouyssié, Bashir Sadet

Publikováno v: Molecules
Molecules, MDPI, 2020, 25 (10), ⟨10.3390/molecules25102348⟩
Molecules, Vol 25, Iss 2348, p 2348 (2020)
Molecules, MDPI, 2020, 25 (10), pp.2348. ⟨10.3390/molecules25102348⟩
Volume 25
Issue 10

To date, Mycobacterium tuberculosis (Mtb) remains the world&rsquo
s greatest infectious killer. The rise of multidrug-resistant strains stresses the need to identify new therapeutic targets to fight the epidemic. We previously demonstrated that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8838b1769022df0c7ca8643a71f19f74
https://hal-cnrs.archives-ouvertes.fr/hal-03019026

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Stable Isotope Labeling Highlights Enhanced Fatty Acid and Lipid Metabolism in Human Acute Myeloid Leukemia

Autor: Laure Tonini, Fanny Viars, Marie Sabatier, Justine Bertrand-Michel, Lucille Stuani, Jean-Emmanuel Sarry, Jean-Charles Portais, Fabien Riols, Pierre Millard, Aurélie Batut, Sonia Zaghdoudi, Estelle Saland, Laetitia K. Linares

Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, MDPI, 2018, 19 (11), pp.3325. ⟨10.3390/ijms19113325⟩
International Journal of Molecular Sciences, MDPI, 2018, 19 (11), pp.1-18. ⟨10.3390/ijms19113325⟩
International Journal of Molecular Sciences 11 (19), 1-18. (2018)
International Journal of Molecular Sciences, 2018, 19 (11), pp.3325. ⟨10.3390/ijms19113325⟩
International Journal of Molecular Sciences, Vol 19, Iss 11, p 3325 (2018)
Volume 19
Issue 11

Background: In Acute Myeloid Leukemia (AML), a complete response to chemotherapy is usually obtained after conventional chemotherapy but overall patient survival is poor due to highly frequent relapses. As opposed to chronic myeloid leukemia, B lymph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1f1fe54bc1a40cc47b8431b8adcd7df
https://www.hal.inserm.fr/inserm-02465183

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IDH1 Mutation Enhances Catabolic Flexibility and Mitochondrial Dependencies to Favor Drug Resistance in Acute Myeloid Leukemia

Autor: Héléna Boutzen, Clément Larrue, Pierre Millard, Laurent Fernando, Laurent Le Cam, Laurie Gayte, Noémie Gadaud, Tony Kaoma, Pierre-Luc Mouchel, Evgenia Turtoi, Jean-Charles Portais, Nesrine Aroua, Justine Bertrand-Michel, Courtney Dinardo, Tony Lionel Palama, Yves Collette, Camille Montersino, Laure Tonini, Yves Gibon, Madi Y. Cissé, Cédric Cassan, Koichi Takahashi, Florence Castelli, Pierre Bories, Audrey Bidet, Joe Marszalek, Martin Carroll, Guillaume Cazals, Claire Calmettes, Arnaud Pigneux, Thomas Farge, Lucille Stuani, Feng Wang, Fabien Jourdan, Laetitia K. Linares, Mary A. Selak, Lara Gales, Andrew M. Futreal, Mathilde Gotanègre, Maud Heuillet, Kiyomi Morita, Jean-Emmanuel Sarry, Andrei Turtoi, Nicolas Broin, Christian Recher, Marina Konopleva, Mohsen Hosseini, Christophe Junot, Claudie Bosc, Emeline Chu-Van, Marine Fraisse, Nathalie Saint-Laurent, Lindsay Peyriga, Rémy Castellano, Estelle Saland, Natalia Baran, Norbert Vey, Frédéric Lopez, Floriant Bellvert, Marie Sabatier, Nathalie Poupin

Publikováno v: SSRN Electronic Journal.

Isocitrate dehydrogenases (IDH) are involved in redox control and central metabolism. We hypothesized that key metabolic fluxes are selectively reprogrammed to maintain biosynthetic homeostasis and lower drug responses in IDH mutant acute myeloid leu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c1ba1581b47f07f178516f5bad74221b
https://doi.org/10.2139/ssrn.3255557

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Bacterial protein-O-mannosylating enzyme is crucial for virulence of Mycobacterium tuberculosis

Autor: Laure Tonini, David Bouyssié, Wladimir Malaga, Mary Jackson, Alexandre Stella, Jérôme Nigou, Chia-Fang Liu, Mathilde Beau, Michel Rivière, Odile Burlet-Schiltz, Christophe Guilhot, Germain Puzo

A posttranslational protein O -mannosylation process resembling that found in fungi and animals has been reported in the major human pathogen Mycobacterium tuberculosis (Mtb) and related actinobacteria. However, the role and incidence of this process

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce099a6cad686588533616816a59f3eb
https://europepmc.org/articles/PMC3631654/

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Cetuximab Fab and Fc N-glycan fast characterization using IdeS digestion and liquid chromatography coupled to electrospray ionization mass spectrometry

Autor: Marie-Claire, Janin-Bussat, Laure, Tonini, Céline, Huillet, Olivier, Colas, Christine, Klinguer-Hamour, Nathalie, Corvaïa, Alain, Beck

Publikováno v: Methods in molecular biology (Clifton, N.J.). 988

Antibodies and related products represent one of the fastest growing areas of new drug development within the pharmaceutical industry. Monoclonal antibodies (mAbs) undergo many posttranslational modifications (PTMs) that must be extensively character

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f81d31722181f3e0c46210d6996fab49
https://pubmed.ncbi.nlm.nih.gov/23475716

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Cetuximab Fab and Fc N-Glycan Fast Characterization Using IdeS Digestion and Liquid Chromatography Coupled to Electrospray Ionization Mass Spectrometry

Autor: Alain Beck, Laure Tonini, Christine Klinguer-Hamour, Olivier Colas, Marie-Claire Janin-Bussat, Nathalie Corvaia, Céline Huillet

Publikováno v: Methods in Molecular Biology ISBN: 9781627033268

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b15db59fe9215558b1d5f9b7e47e9546
https://doi.org/10.1007/978-1-62703-327-5_7

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