Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Laure Thibaudeau"'
Autor:
Laure Thibaudeau, Anna V. Taubenberger, Boris M. Holzapfel, Verena M. Quent, Tobias Fuehrmann, Parisa Hesami, Toby D. Brown, Paul D. Dalton, Carl A. Power, Brett G. Hollier, Dietmar W. Hutmacher
Publikováno v:
Disease Models & Mechanisms, Vol 7, Iss 2, Pp 299-309 (2014)
The skeleton is a preferred homing site for breast cancer metastasis. To date, treatment options for patients with bone metastases are mostly palliative and the disease is still incurable. Indeed, key mechanisms involved in breast cancer osteotropism
Externí odkaz:
https://doaj.org/article/658332c5ae134b51b4a6cbcbfec323c3
Autor:
Ferdinand Wagner, Laure Thibaudeau, Jean-Pierre Levesque, Dietmar W. Hutmacher, Boris Michael Holzapfel
Publikováno v:
ResearcherID
STEM CELLS
STEM CELLS
Despite positive testing in animal studies, more than 80% of novel drug candidates fail to proof their efficacy when tested in humans. This is primarily due to the use of preclinical models that are not able to recapitulate the physiological or patho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efa474bc5df112cdda454e97071b13dc
https://doi.org/10.1002/stem.1978
https://doi.org/10.1002/stem.1978
Autor:
Ladan Fazli, Boris Michael Holzapfel, Judith A. Clements, Martine Roudier, Parisa Hesami, Anna Taubenberger, Laure Thibaudeau, Dietmar W. Hutmacher, Laura S. Gregory, Shirly Sieh
Publikováno v:
Clinical & Experimental Metastasis. 31:435-446
Currently used xenograft models for prostate cancer bone metastasis lack the adequate tissue composition necessary to study the interactions between human prostate cancer cells and the human bone microenvironment. We introduce a tissue engineering ap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edf59ccb51f717365564e172b5812f43
https://doi.org/10.1007/s10585-014-9638-5
https://doi.org/10.1007/s10585-014-9638-5
Autor:
Parisa Hesami, Dietmar W. Hutmacher, Boris Michael Holzapfel, Carl Power, Paul D. Dalton, Toby D. Brown, Brett G. Hollier, Verena M.C. Quent, Anna Taubenberger, Tobias Fuehrmann, Laure Thibaudeau
Publikováno v:
Disease Models & Mechanisms, Vol 7, Iss 2, Pp 299-309 (2014)
Disease Models & Mechanisms
Disease Models & Mechanisms
The skeleton is a preferred homing site for breast cancer metastasis. To date, treatment options for patients with bone metastases are mostly palliative and the disease is still incurable. Indeed, key mechanisms involved in breast cancer osteotropism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d121ef4f772fa9277e1434663b012565
http://dmm.biologists.org/content/7/2/299
http://dmm.biologists.org/content/7/2/299
Autor:
Laure Thibaudeau
Publikováno v:
Psychanalyse. :75
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ca20c432c5bdde6d2a55bb8ada7deff
https://doi.org/10.3917/psy.044.0075
https://doi.org/10.3917/psy.044.0075
Autor:
Dietmar W. Hutmacher, Anna Taubenberger, Laure Thibaudeau, Verena M.C. Quent, Judith A. Clements
Publikováno v:
Journal of Bone and Mineral Research. 28:1399-1411
Free to read The mechanisms leading to colonization of metastatic breast cancer cells (BCa) in the skeleton are still not fully understood. Here, we demonstrate that mineralized extracellular matrices secreted by primary human osteoblasts (hOBM) modu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9847b75e922c11dffea19e857e75ab20
https://doi.org/10.1002/jbmr.1875
https://doi.org/10.1002/jbmr.1875
Autor:
Anna Taubenberger, Dietmar W. Hutmacher, Laure Thibaudeau, Boris Michael Holzapfel, Carl Power, Parisa Hesami, Nina Pauline Holzapfel, Pamela J. Russell, Susanne Mayer-Wagner, Judith A. Clements
Publikováno v:
Cancer and Metastasis Reviews. 32:129-145
The determinants and key mechanisms of cancer cell osteotropism have not been identified, mainly due to the lack of reproducible animal models representing the biological, genetic and clinical features seen in humans. An ideal model should be capable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eca01758b95df3b8cf8a3838024a618
https://doi.org/10.1007/s10555-013-9437-5
https://doi.org/10.1007/s10555-013-9437-5
Autor:
Laure Thibaudeau
Publikováno v:
Psychanalyse. 41:79
La mort est le fondement de la vie humaine, ce que refuse l’ordre phallique, qui pourtant en est porteur. Il s’y oppose par le dementi. Mais le symptome denonce ce dementi du langage, la ou celui-ci manque a dire. Ces deux positions vont s’affr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67da7626225ee73977eb4b54863be17c
https://doi.org/10.3917/psy.041.0079
https://doi.org/10.3917/psy.041.0079
Publikováno v:
Oncotarget
Bone metastasis is a frequent and life-threatening complication of breast cancer. The molecular mechanisms supporting the establishment of breast cancer cells in the skeleton are still not fully understood, which may be attributed to the lack of suit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3260b431239bc3fed68b2c2d66a72a51
https://europepmc.org/articles/PMC4612107/
https://europepmc.org/articles/PMC4612107/
Autor:
Boris Michael Holzapfel, Daniela Loessner, Judith A. Clements, Jean-Pierre Levesque, Ingrid G. Winkler, John D. Hooper, Bianca Nowlan, Allison R. Pettit, Dietmar W. Hutmacher, Laure Thibaudeau, Pamela J. Russell, Christina Theodoropoulos, Valerie Barbier
Publikováno v:
Biomaterials. 61
Advances in tissue-engineering have resulted in a versatile tool-box to specifically design a tailored microenvironment for hematopoietic stem cells (HSCs) in order to study diseases that develop within this setting. However, most current in vivo mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8f1c089aa523c3ac80a3020f09d7a64
https://pubmed.ncbi.nlm.nih.gov/26001075
https://pubmed.ncbi.nlm.nih.gov/26001075