Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Laure Maigre"'
Autor:
Anas Allam, Laure Maigre, Julia Vergalli, Estelle Dumont, Bertrand Cinquin, Rodolphe Alves de Sousa, Jelena Pajovic, Elizabeth Pinet, Nikaia Smith, Jean-Philippe Herbeuval, Matthieu Réfrégiers, Isabelle Artaud, Jean-Marie Pagès
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract A main challenge in chemotherapy is to determine the in cellulo parameters modulating the drug concentration required for therapeutic action. It is absolutely urgent to understand membrane permeation and intracellular concentration of antibi
Externí odkaz:
https://doaj.org/article/ca80691df79d435fac589a85f21b0920
Autor:
Nadège Philippe, Laure Maigre, Sébastien Santini, Elizabeth Pinet, Jean-Michel Claverie, Anne-Véronique Davin-Régli, Jean-Marie Pagès, Muriel Masi
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0138828 (2015)
Infections caused by multidrug resistant (MDR) bacteria are a major concern worldwide. Changes in membrane permeability, including decreased influx and/or increased efflux of antibiotics, are known as key contributors of bacterial MDR. Therefore, it
Externí odkaz:
https://doaj.org/article/656299a35a384f29ab98bd23d14ec3bb
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e38624 (2012)
A molecular definition of the mechanism conferring bacterial multidrug resistance is clinically crucial and today methods for quantitative determination of the uptake of antimicrobial agents with single cell resolution are missing. Using the naturall
Externí odkaz:
https://doaj.org/article/6c7260a8978e4a01b3d3dfb39b839809
Autor:
Estelle Dumont, Julia Vergalli, Rodolphe Alves de Sousa, Laure Maigre, Isabelle Artaud, Jean-Marie Pagès, Anas Allam
Publikováno v:
European Journal of Medicinal Chemistry. 127:748-756
Structure of bacterial envelope is one of the major factors contributing to Gram negative bacterial resistance. To develop new agents that target the bacterial membranes, we synthesized, by analogy with our previous peptide conjugates, new amphiphili
Autor:
Laure Maigre, Jelena Pajovic, Bertrand Cinquin, Jean-Marie Pagès, Muriel Masi, Julia Vergalli, Matthieu Réfrégiers, Estelle Dumont
Publikováno v:
Nature Protocols
Nature Protocols, Nature Publishing Group, 2018, 13 (6), pp.1348-1361. ⟨10.1038/nprot.2018.036⟩
Nature Protocols, 2018, 13 (6), pp.1348-1361. ⟨10.1038/nprot.2018.036⟩
Nature Protocols, Nature Publishing Group, 2018, 13 (6), pp.1348-1361. ⟨10.1038/nprot.2018.036⟩
Nature Protocols, 2018, 13 (6), pp.1348-1361. ⟨10.1038/nprot.2018.036⟩
International audience; The efficacy of antibacterial molecules depends on their capacity to reach inhibitory concentrations in the vicinity of their target. This is particularly challenging for drugs directed against Gram-negative bacteria, which ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::660251e4170e060504c0516addb4ab86
https://hal-amu.archives-ouvertes.fr/hal-01824361
https://hal-amu.archives-ouvertes.fr/hal-01824361
Autor:
Tommaso D'Agostino, Que-Tien Tran, Jean-Marie Pagès, Mathias Winterhalter, Anne Davin-Regli, Matteo Ceccarelli, Laure Maigre
Epidemiologically unrelated Providencia stuartii strains isolated in hospitals in the south of France were investigated for their porin sequences and profiles. Noticeable resistance to β-lactams was found to be associated with production of extend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::259eff9b3d3da848b9105490a4e5ec32
http://www.elsevier.com/wps/find/journaldescription.cws_home/522493/description#description
http://www.elsevier.com/wps/find/journaldescription.cws_home/522493/description#description
Autor:
Thierry Meinnel, Karim Hamiche, Rodolphe Alves de Sousa, Carmela Giglione, Laure Maigre, Alexis Denis, Sonia Fieulaine, Jean-Michel Bolla, Isabelle Artaud, Mickael Alimi, Abbass Taleb, Jean-Marie Pagès
Publikováno v:
Scientific Reports
Scientific Reports, Nature Publishing Group, 2017, 7, pp.39365. ⟨10.1038/srep39365⟩
Scientific Reports, 2017, 7, pp.39365. ⟨10.1038/srep39365⟩
Scientific Reports, Nature Publishing Group, 2017, 7, pp.39365. ⟨10.1038/srep39365⟩
Scientific Reports, 2017, 7, pp.39365. ⟨10.1038/srep39365⟩
Peptide deformylase (PDF) is considered an excellent target to develop antibiotics. We have performed an extensive characterization of a new PDF from the pathogen Streptococcus agalactiae, showing properties similar to other known PDFs. S. agalactiae
Autor:
Jean-Marie Pagès, Michael Mourez, Estelle Dumont, Bertrand Cinquin, Julia Vergalli, Laure Maigre, Jelena Pajovic, Eric Bacqué, Matthieu Réfrégiers
Publikováno v:
Scientific Reports
Scientific Reports, 2017, 7 (1), pp.9821 ⟨10.1038/s41598-017-08775-4⟩
Scientific Reports, Nature Publishing Group, 2017, 7 (1), pp.9821 ⟨10.1038/s41598-017-08775-4⟩
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Scientific Reports, 2017, 7 (1), pp.9821 ⟨10.1038/s41598-017-08775-4⟩
Scientific Reports, Nature Publishing Group, 2017, 7 (1), pp.9821 ⟨10.1038/s41598-017-08775-4⟩
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Bacterial multidrug resistance is a worrying health issue. In Gram-negative antibacterial research, the challenge is to define the antibiotic permeation across the membranes. Passing through the membrane barrier to reach the inhibitory concentration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f9d5a54f2a24ce55e396e594c137a11
https://doi.org/10.1038/s41598-017-08775-4
https://doi.org/10.1038/s41598-017-08775-4
Autor:
Laure Maigre, Jean-Marie Pagès, Anas Allam, Julia Vergalli, Jelena Pajovic, Jean-Philippe Herbeuval, Elizabeth Pinet, Nikaïa Smith, Estelle Dumont, Bertrand Cinquin, Rodolphe Alves de Sousa, Matthieu Réfrégiers, Isabelle Artaud
Publikováno v:
Scientific Reports
Scientific Reports, Nature Publishing Group, 2017, 7, pp.986. ⟨https://www.nature.com/articles/s41598-017-00945-8⟩. ⟨10.1038/s41598-017-00945-8⟩
Scientific Reports, Nature Publishing Group, 2017, 7 (1), pp.986. ⟨10.1038/s41598-017-00945-8⟩
Scientific Reports, Nature Publishing Group, 2017, 7, pp.986. 〈https://www.nature.com/articles/s41598-017-00945-8〉. 〈10.1038/s41598-017-00945-8〉
Scientific Reports, 2017, 7 (1), pp.986. ⟨10.1038/s41598-017-00945-8⟩
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Scientific Reports, Nature Publishing Group, 2017, 7, pp.986. ⟨https://www.nature.com/articles/s41598-017-00945-8⟩. ⟨10.1038/s41598-017-00945-8⟩
Scientific Reports, Nature Publishing Group, 2017, 7 (1), pp.986. ⟨10.1038/s41598-017-00945-8⟩
Scientific Reports, Nature Publishing Group, 2017, 7, pp.986. 〈https://www.nature.com/articles/s41598-017-00945-8〉. 〈10.1038/s41598-017-00945-8〉
Scientific Reports, 2017, 7 (1), pp.986. ⟨10.1038/s41598-017-00945-8⟩
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
International audience; A main challenge in chemotherapy is to determine the in cellulo parameters modulating the drug concentration required for therapeutic action. It is absolutely urgent to understand membrane permeation and intracellular concentr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15971de99f239b702b1a57d18440529d
https://hal.archives-ouvertes.fr/hal-01511162
https://hal.archives-ouvertes.fr/hal-01511162
Autor:
Bertrand Cinquin, Jean-Marie Pagès, Robert A. Stavenger, Elizabeth Pinet, Scott D. Mills, Laure Maigre, Matthieu Réfrégiers, Jacqueline Chevalier
Publikováno v:
Scientific Reports
Scientific Reports, Nature Publishing Group, 2016, 5 (1), pp.17968-17968. ⟨10.1038/srep17968⟩
Scientific Reports, 2016, 5 (1), pp.17968-17968. ⟨10.1038/srep17968⟩
Scientific Reports, 2015, 5, pp.17968. ⟨10.1038/srep17968⟩
Scientific Reports, Nature Publishing Group, 2015, 5, pp.17968. ⟨10.1038/srep17968⟩
Scientific Reports, Nature Publishing Group, 2016, 5 (1), pp.17968-17968. ⟨10.1038/srep17968⟩
Scientific Reports, 2016, 5 (1), pp.17968-17968. ⟨10.1038/srep17968⟩
Scientific Reports, 2015, 5, pp.17968. ⟨10.1038/srep17968⟩
Scientific Reports, Nature Publishing Group, 2015, 5, pp.17968. ⟨10.1038/srep17968⟩
International audience; Bacterial multidrug resistance is a significant health issue. A key challenge, particularly in Gram-negative antibacterial research, is to better understand membrane permeation of antibiotics in clinically relevant bacterial p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ffe61d0644f9c9c0f9a70e9ffbc5da5
https://hal-amu.archives-ouvertes.fr/hal-01831684
https://hal-amu.archives-ouvertes.fr/hal-01831684