Výsledky vyhledávání - "Laure Gluais"

Akademický článek

Crystal structure and functional analysis of the SARS-coronavirus RNA cap 2'-O-methyltransferase nsp10/nsp16 complex.

Autor: Etienne Decroly, Claire Debarnot, François Ferron, Mickael Bouvet, Bruno Coutard, Isabelle Imbert, Laure Gluais, Nicolas Papageorgiou, Andrew Sharff, Gérard Bricogne, Miguel Ortiz-Lombardia, Julien Lescar, Bruno Canard

Publikováno v: PLoS Pathogens, Vol 7, Iss 5, p e1002059 (2011)

Cellular and viral S-adenosylmethionine-dependent methyltransferases are involved in many regulated processes such as metabolism, detoxification, signal transduction, chromatin remodeling, nucleic acid processing, and mRNA capping. The Severe Acute R

Externí odkaz: https://doaj.org/article/5ede7db0af914726a3936efe63df46f1

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Les enzymes de la réplication/transcription chez les coronavirus

Autor: Lorenzo, Subissi, Étienne, Decroly, Mickaël, Bouvet, Laure, Gluais, Bruno, Canard, Isabelle, Imbert

Publikováno v: Virologie (Montrouge, France). 16(4)

The discovery of a new coronavirus (CoV) as the causative agent of the severe acute respiratory syndrome (SARS) pandemic outbreak in 2003 has stimulated a number of studies on the molecular biology of SARS-CoV and related viruses. This research has p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2303e8e45577d1d731d8dfebf28b7fa0
https://pubmed.ncbi.nlm.nih.gov/33065881

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Stratégies de formation de la structure coiffe chez les virus à ARN

Autor: Barbara Selisko, Mickaël Bouvet, Bruno Coutard, Laure Gluais, François Ferron, Etienne Decroly, Bruno Canard, Isabelle Imbert

Publikováno v: médecine/sciences. 28:423-429

Most viruses use the mRNA-cap dependent cellular translation machinery to translate their mRNAs into proteins. The addition of a cap structure at the 5' end of mRNA is therefore an essential step for the replication of many virus families. Additional

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ab3712fb8e0381ed00cdfc53ae111f70
https://doi.org/10.1051/medsci/2012284021

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RNA 3'-end mismatch excision by the severe acute respiratory syndrome coronavirus nonstructural protein nsp10/nsp14 exoribonuclease complex

Autor: Bruno Canard, Laure Gluais, Etienne Decroly, Mickaël Bouvet, Lorenzo Subissi, Isabelle Imbert

Publikováno v: Proceedings of the National Academy of Sciences; Vol 109
HEALTH FP7 Publications Database
PubMed Central
Proceedings of the National Academy of Sciences

The replication/transcription complex of severe acute respiratory syndrome coronavirus is composed of at least 16 nonstructural proteins (nsp1–16) encoded by the ORF-1a/1b. This complex includes replication enzymes commonly found in positive-strand

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d6a9e7729fd7b1da06e9a30ac1d1ae0

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The active conformation of human glucokinase is not altered by allosteric activators

Autor: Laurent Vuillard, Renaud Vincentelli, Jean A. Boutin, Mathias Antoine, Gilles Ferry, Amandine Lagarde, Pierre Petit, Laure Gluais

Publikováno v: Acta Crystallographica Section D Biological Crystallography. 67:929-935

Glucokinase (GK) catalyses the formation of glucose 6-phosphate from glucose and ATP. A specific feature of GK amongst hexokinases is that it can cycle between active and inactive conformations as a function of glucose concentration, resulting in a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9792dc2873a8cc41e0c6062cb3b29b79
https://doi.org/10.1107/s0907444911036729

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[Capping strategies in RNA viruses]

Autor: Mickaël, Bouvet, François, Ferron, Isabelle, Imbert, Laure, Gluais, Barbara, Selisko, Bruno, Coutard, Bruno, Canard, Etienne, Decroly

Publikováno v: Medecine sciences : M/S. 28(4)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::dcbaa9340a9f81a9e72286db21c94180
https://pubmed.ncbi.nlm.nih.gov/22549871

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Crystallization and diffraction analysis of the SARS coronavirus nsp10-nsp16 complex

Autor: Claire Debarnot, Bruno Canard, Isabelle Varlet, François Ferron, Laure Gluais, Mickaël Bouvet, Etienne Decroly, Julien Lescar, Nicolas Papageorgiou, Isabelle Imbert

Publikováno v: Acta crystallographica. Section F, Structural biology communications
Acta crystallographica. Section F, Structural biology communications, John Wiley & Sons Ltd, 2011, 67 (Pt 3), pp.404-8. ⟨10.1107/S1744309111002867⟩
Acta Crystallographica Section F Structural Biology and Crystallization Communications
Acta crystallographica Section F : Structural biology communications [2014-...]
Acta crystallographica Section F : Structural biology communications [2014-..], 2011, 67 (Pt 3), pp.404-8. ⟨10.1107/S1744309111002867⟩

International audience; To date, the SARS coronavirus is the only known highly pathogenic human coronavirus. In 2003, it was responsible for a large outbreak associated with a 10% fatality rate. This positive RNA virus encodes a large replicase polyp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39ae6cc3d0525ee8b49c1763a57ed884
https://hal.archives-ouvertes.fr/hal-00751530

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Crystal Structure and Functional Analysis of the SARS-Coronavirus RNA Cap 2′-O-Methyltransferase nsp10/nsp16 Complex

Autor: François Ferron, Claire Debarnot, Bruno Canard, Andrew J. Sharff, Etienne Decroly, Julien Lescar, Gérard Bricogne, Bruno Coutard, Nicolas Papageorgiou, Isabelle Imbert, Miguel Ortiz-Lombardía, Laure Gluais, Mickaël Bouvet

Publikováno v: PLoS Pathogens
PLoS Pathogens, Vol 7, Iss 5, p e1002059 (2011)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ef2ea7c6c2901342770e6c4ad294f00
https://doi.org/10.1371/journal.ppat.1002059

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