Výsledky vyhledávání - "Laure, Gibault"

Akademický článek

Best imaging signs identified by radiomics could outperform the model: application to differentiating lung carcinoid tumors from atypical hamartomas

Autor: Paul Habert, Antoine Decoux, Lilia Chermati, Laure Gibault, Pascal Thomas, Arthur Varoquaux, Françoise Le Pimpec-Barthes, Armelle Arnoux, Loïc Juquel, Kathia Chaumoitre, Stéphane Garcia, Jean-Yves Gaubert, Loïc Duron, Laure Fournier

Publikováno v: Insights into Imaging, Vol 14, Iss 1, Pp 1-12 (2023)

Abstract Objectives Lung carcinoids and atypical hamartomas may be difficult to differentiate but require different treatment. The aim was to differentiate these tumors using contrast-enhanced CT semantic and radiomics criteria. Methods Between Novem

Externí odkaz: https://doaj.org/article/cd6cf00b1ada4b1f859123688dc5e488

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Akademický článek

Clinical and molecular characteristics associated with high PD-L1 expression in EGFR-mutated lung adenocarcinoma.

Autor: Jeremy Slomka, Hugo Berthou, Audrey Mansuet-Lupo, Hélène Blons, Elizabeth Fabre, Ivan Lerner, Bastien Rance, Marco Alifano, Jeanne Chapron, Gary Birsen, Laure Gibault, Jennifer Arrondeau, Karen Leroy, Marie Wislez

Publikováno v: PLoS ONE, Vol 19, Iss 11, p e0307161 (2024)

ObjectiveRecent evidence suggests that elevated levels of PD-L1 expression may be linked to early resistance to TKI and reduced survival in NSCLC with EGFR mutations. This study aimed to characterize the clinical and molecular features of EGFR-mutate

Externí odkaz: https://doaj.org/article/ab6f3588f8cc47caa87e83f6b1a1c71b

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Akademický článek

A novel Chr1-miR-200 driven whole transcriptome signature shapes tumor immune microenvironment and predicts relapse in early-stage lung adenocarcinoma

Autor: Simon Garinet, Audrey Didelot, Laetitia Marisa, Guillaume Beinse, Marine Sroussi, Françoise Le Pimpec-Barthes, Elizabeth Fabre, Laure Gibault, Pierre Laurent-Puig, Sophie Mouillet-Richard, Antoine Legras, Hélène Blons

Publikováno v: Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-12 (2023)

Abstract Background In Lung adenocarcinoma (LUAD), targeted therapies and immunotherapies have moved from metastatic to early stage and stratification of the relapse risk becomes mandatory. Here we identified a miR-200 based RNA signature that deline

Externí odkaz: https://doaj.org/article/904733005c644c07940174895ea01e79

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Akademický článek

Development and validation of a rabbit model of Pseudomonas aeruginosa non-ventilated pneumonia for preclinical drug development

Publikováno v: Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)

BackgroundNew drugs targeting antimicrobial resistant pathogens, including Pseudomonas aeruginosa, have been challenging to evaluate in clinical trials, particularly for the non-ventilated hospital-acquired pneumonia and ventilator-associated pneumon

Externí odkaz: https://doaj.org/article/711b678c4c3e47ab9251fd8fcab51201

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Akademický článek

Transbronchial cryobiopsy proven amyloid diffuse cystic lung disease complicating a transthyretin mutated (ATTRm) amyloidosis: a case report

Autor: Sébastien Gaultier, Tania Puscas, Jean Pastre, Laure Gibault, Jean-Benoît Arlet, Cécile Cauquil, Adrien Michon

Publikováno v: Therapeutic Advances in Respiratory Disease, Vol 17 (2023)

We present a case report of transbronchial cryobiopsy proven diffuse amyloid cystic lung disease complicating a homozygous Val122Ile (V122I) transthyretin mutated amyloidosis (ATTRm). To the best of our knowledge, this is the first case in the litera

Externí odkaz: https://doaj.org/article/7b8d6234072a417f8c3b8933623c3265

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Akademický článek

Multi-site tumor sampling highlights molecular intra-tumor heterogeneity in malignant pleural mesothelioma

Publikováno v: Genome Medicine, Vol 13, Iss 1, Pp 1-16 (2021)

Abstract Background Malignant pleural mesothelioma (MPM) is a heterogeneous cancer. Better knowledge of molecular and cellular intra-tumor heterogeneity throughout the thoracic cavity is required to develop efficient therapies. This study focuses on

Externí odkaz: https://doaj.org/article/f28dbb2176c54bca878c197186dd3f4f

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Akademický článek

Genetic alterations of malignant pleural mesothelioma: association with tumor heterogeneity and overall survival

Publikováno v: Molecular Oncology, Vol 14, Iss 6, Pp 1207-1223 (2020)

Development of precision medicine for malignant pleural mesothelioma (MPM) requires a deep knowledge of tumor heterogeneity. Histologic and molecular classifications and histo‐molecular gradients have been proposed to describe heterogeneity, but a

Externí odkaz: https://doaj.org/article/69f3c9f25b93468ea781ad245bb37fda

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Akademický článek

CXCR6 deficiency impairs cancer vaccine efficacy and CD8+ resident memory T-cell recruitment in head and neck and lung tumors

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 9, Iss 3 (2021)

Background Resident memory T lymphocytes (TRM) are located in tissues and play an important role in immunosurveillance against tumors. The presence of TRM prior to treatment or their induction is associated to the response to anti-Programmed cell dea

Externí odkaz: https://doaj.org/article/7396a1c31d234ef2b59347b1a9805e52

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Lung allograft standardized histological analysis (LASHA) template

Autor: Fiorella Calabrese, Anja C. Roden, Elizabeth Pavlisko, Francesca Lunardi, Desley Neil, Benjamin Adam, David Hwang, Martin Goddard, Gerald J. Berry, Marina Ivanovic, Jan von der Thüsen, Laure Gibault, Chieh-Yu Lin, Katharina Wassilew, Carolyn Glass, Glen Westall, Adriana Zeevi, Deborah Jo Levine, Antoine Roux

Publikováno v: Journal of Heart and Lung Transplantation, 41(10), 1487-1500. Elsevier Inc.

Background: Routine monitoring of lung-transplanted patients is crucial for the identification of immunological and non-immunological complications. Determining the etiology of acute allograft dysfunction, particularly in alloimmune-mediated disorder

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d7268bb0d3d199425ee7ae8fb92100c
http://www.scopus.com/inward/record.url?scp=85135303512&partnerID=8YFLogxK

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