Zobrazeno 1 - 10 of 11 pro vyhledávání: '"Laura-Marie A. Nucho"'
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Akademický článek
Induced pluripotent stem cell-derived enteric neural crest cells repopulate human aganglionic tissue-engineered intestine to form key components of the enteric nervous system
Autor: David F Chang, Samuel M Zuber, Elizabeth A Gilliam, Laura-Marie A Nucho, Gabriel Levin, Fengnan Wang, Anthony I Squillaro, Sha Huang, Jason R Spence, Tracy C Grikscheit
Publikováno v: Journal of Tissue Engineering, Vol 11 (2020)
Models for enteric neuropathies, in which intestinal nerves are absent or injured, are required to evaluate possible cell therapies. However, existing options, including transgenic mice, are variable and fragile. Here immunocompromised mice were impl
Externí odkaz: https://doaj.org/article/43a0ff71f3164e6389e1528d88f8041d
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2
NH2-terminal deletion of specific phosphorylation sites on PHOX2B disrupts the formation of enteric neurons in vivo
Autor: Laura-Marie A. Nucho, Anthony I. Squillaro, Kathryn M. Maselli, Jason R. Spence, Tracy C. Grikscheit, David F. Chang, Elizabeth A. Gilliam, Sha Huang, Samuel M. Zuber, Yevheniya Shevchenko, Jazmin Garcia
Publikováno v: American Journal of Physiology-Gastrointestinal and Liver Physiology. 320:G1054-G1066
Mutations in the paired-like homeobox 2 b (PHOX2B) gene are associated with congenital central hypoventilation syndrome (CCHS), which is a rare condition in which both autonomic dysregulation with hypoventilation and an enteric neuropathy may occur.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c5ee74c59ae6c3f761d92f2a6b3b4795
https://doi.org/10.1152/ajpgi.00073.2021
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6
Spleen Organoid Units Generate Functional Human and Mouse Tissue-Engineered Spleen in a Murine Model
Autor: Laura-Marie A. Nucho, Samuel M. Zuber, Alexa Fode, Anthony I. Squillaro, Kristin M. Gee, Kathryn L. Fowler, Tracy C. Grikscheit, Mubina A. Isani, Kathryn M. Maselli
Publikováno v: Tissue engineering. Part A. 26(7-8)
Introduction: Splenectomy is common after trauma or hematologic disease, and alters immune protection against pathogens, which may lead to fulminant infection with high mortality. Yet the spleen has demonstrable regenerative capacity and cells might
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a81ec3e5e3efc79c8e25d31a4cae13fb
https://pubmed.ncbi.nlm.nih.gov/31696780
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7
Induced pluripotent stem cell-derived enteric neural crest cells repopulate human aganglionic tissue-engineered intestine to form key components of the enteric nervous system
Autor: Anthony I. Squillaro, Samuel M. Zuber, Gabriel Levin, Jason R. Spence, David F. Chang, Elizabeth A. Gilliam, Sha Huang, Tracy C. Grikscheit, Laura-Marie A. Nucho, Fengnan Wang
Publikováno v: Journal of Tissue Engineering
Journal of Tissue Engineering, Vol 11 (2020)
Models for enteric neuropathies, in which intestinal nerves are absent or injured, are required to evaluate possible cell therapies. However, existing options, including transgenic mice, are variable and fragile. Here immunocompromised mice were impl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1873573d8415aae2bb93a1871df7a6aa
https://pubmed.ncbi.nlm.nih.gov/32435442
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