Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Laura-M. Dutca"'
Autor:
Nickolas A. Boehme, Adam Hedberg-Buenz, Nicole Tatro, Michael Bielecki, William C. Castonguay, Todd E. Scheetz, Michael G. Anderson, Laura M. Dutca
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-19 (2021)
Abstract Traumatic brain injuries (TBI) of varied types are common across all populations and can cause visual problems. For military personnel in combat settings, injuries from blast exposures (bTBI) are prevalent and arise from a myriad of differen
Externí odkaz:
https://doaj.org/article/ccfdf23006a846fa89fdb7f62743a8b4
Autor:
Jaymie R. Voorhees, Matthew T. Remy, Claire M. Erickson, Laura M. Dutca, Daniel J. Brat, Andrew A. Pieper
Publikováno v:
npj Aging and Mechanisms of Disease, Vol 5, Iss 1, Pp 1-14 (2019)
Occupational exposure to toxins may accelerate Alzheimer’s disease The interaction of genes and environment contributes to Alzheimer’s disease (AD). For example, agricultural workers, military personnel, industrial manufacturers, veterinarians, h
Externí odkaz:
https://doaj.org/article/97add60acab14939931cb8b2bbeb72e7
Autor:
Terry C. Yin, Jeremiah K. Britt, Héctor De Jesús-Cortés, Yuan Lu, Rachel M. Genova, Michael Z. Khan, Jaymie R. Voorhees, Jianqiang Shao, Aaron C. Katzman, Paula J. Huntington, Cassie Wassink, Latisha McDaniel, Elizabeth A. Newell, Laura M. Dutca, Jacinth Naidoo, Huxing Cui, Alexander G. Bassuk, Matthew M. Harper, Steven L. McKnight, Joseph M. Ready, Andrew A. Pieper
Publikováno v:
Cell Reports, Vol 8, Iss 6, Pp 1731-1740 (2014)
The P7C3 class of neuroprotective aminopropyl carbazoles has been shown to block neuronal cell death in models of neurodegeneration. We now show that P7C3 molecules additionally preserve axonal integrity after injury, before neuronal cell death occur
Externí odkaz:
https://doaj.org/article/eaf07f99280f4695b3055e2a7c8aa34d
Autor:
Todd E. Scheetz, Carly J. van der Heide, William J. Paradee, Nicholas Pomernackas, Maurisa Mansaray, Demelza R. Larson, S. Scott Whitmore, Adam Hedberg-Buenz, Kai Wang, Laura M. Dutca, Kacie J. Meyer, Hannah E. Mercer, K. Saidas Nair, Swanand Koli, Michael G. Anderson
Central corneal thickness is a quantitative trait with important associations to human health. In a phenotype-driven approach studying corneal thickness of congenic derivatives of C57BLKS/J and SJL/J mice, the critical region for a quantitative trait
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67a1acf5c1cc7a573c55963361b24d73
https://doi.org/10.1101/2021.09.22.461410
https://doi.org/10.1101/2021.09.22.461410
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose The purpose of this study was to examine the influence of genetic background on the retinal ganglion cell (RGC) response to blast-mediated traumatic brain injury (TBI) in Jackson Diversity Outbred (J:DO), C57BL/6J and BALB/cByJ mice. Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0839545830575de86587ca9b5c8e709e
https://pubmed.ncbi.nlm.nih.gov/34106210
https://pubmed.ncbi.nlm.nih.gov/34106210
Autor:
Michael Bielecki, Nicole Tatro, Adam Hedberg-Buenz, William C Castonguay, Michael G. Anderson, Todd E. Scheetz, Nickolas Boehme, Laura M. Dutca
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-19 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-19 (2021)
Traumatic brain injuries (TBI) of varied types are common across all populations and can cause visual problems. For military personnel in combat settings, injuries from blast exposures (bTBI) are prevalent and arise from a myriad of different situati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::051c926ff35d9b6304bfe185a5c19b79
https://pubmed.ncbi.nlm.nih.gov/34083587
https://pubmed.ncbi.nlm.nih.gov/34083587
Autor:
Alexander G. Bassuk, Abhigna Akurathi, Elizabeth A. Newell, Brittany P. Todd, Elliot Burghardt, Lucy P. Evans, Matthew M. Harper, Laura M. Dutca, Nickolas Boehme, Vinit B. Mahajan, Shu Wu, Polly J. Ferguson
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose In a mouse model of blast-mediated traumatic brain injury (bTBI), interleukin-1 (IL-1)-pathway components were tested as potential therapeutic targets for bTBI-mediated retinal ganglion cell (RGC) dysfunction. Sex was also evaluated as a vari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8154709234ff0ca959668ef59301692
https://pubmed.ncbi.nlm.nih.gov/33030508
https://pubmed.ncbi.nlm.nih.gov/33030508
Autor:
Nickolas Boehme, Addison W. Woll, Dana A. Soukup, Alexander G. Bassuk, Abhigna Akurathi, Lucy P. Evans, Matthew M. Harper, Michael Delcau, Michael G. Anderson, Laura M. Dutca, Marco M. Hefti, Adam Hedberg-Buenz
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose The purpose of this study was to examine the effect of multiple blast exposures and blast preconditioning on the structure and function of retinal ganglion cells (RGCs), to identify molecular pathways that contribute to RGC loss, and to evalu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ee9f191758a85194c965a2dd955cea8
http://europepmc.org/articles/PMC6785841
http://europepmc.org/articles/PMC6785841
Autor:
Michael Z. Khan, Andrew A. Pieper, Jaymie R. Voorhees, Latisha McDaniel, Matthew T. Remy, Daniel J. Brat, Noelle S. Williams, Eli El Rassi, Coral J. Cintrón-Pérez, Laura M. Dutca, Terry C. Yin
Publikováno v:
Biological Psychiatry. 84:488-498
BACKGROUND: In addition to cognitive deficits, Alzheimer’s disease (AD) is also associated with other neuropsychiatric symptoms, including severe depression. Indeed, depression often precedes cognitive deficits in patients with AD. Unfortunately, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be1e412c94f19c20f9a8fe2ea99891f0
https://doi.org/10.1016/j.biopsych.2017.10.023
https://doi.org/10.1016/j.biopsych.2017.10.023
Autor:
Michael G. Anderson, Anat Galor, Laura M. Dutca, Mona K. Garvin, Victor A. Robles, Danielle S. Rudd
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Scientific Reports
Scientific Reports
Latanoprost is a common glaucoma medication. Here, we study longitudinal effects of sustained latanoprost treatment on intraocular pressure (IOP) in C57BL/6J mice, as well as two potential side-effects, changes in iris pigmentation and central cornea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cf615ff70f7c46259a089fbc41570ed
http://link.springer.com/article/10.1038/s41598-018-31280-1
http://link.springer.com/article/10.1038/s41598-018-31280-1