Výsledky vyhledávání - "Laura di Blasio"

Akademický článek

XENTURION is a population-level multidimensional resource of xenografts and tumoroids from metastatic colorectal cancer patients

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-22 (2024)

Abstract The breadth and depth at which cancer models are interrogated contribute to the successful clinical translation of drug discovery efforts. In colorectal cancer (CRC), model availability is limited by a dearth of large-scale collections of pa

Externí odkaz: https://doaj.org/article/dfe0bea706154ddd9a2dfd94e1c6c5a8

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Akademický článek

Dynamic Interplay between Pericytes and Endothelial Cells during Sprouting Angiogenesis

Autor: Giulia Chiaverina, Laura di Blasio, Valentina Monica, Massimo Accardo, Miriam Palmiero, Barbara Peracino, Marianela Vara-Messler, Alberto Puliafito, Luca Primo

Publikováno v: Cells, Vol 8, Iss 9, p 1109 (2019)

Vascular physiology relies on the concerted dynamics of several cell types, including pericytes, endothelial, and vascular smooth muscle cells. The interactions between such cell types are inherently dynamic and are not easily described with static,

Externí odkaz: https://doaj.org/article/2736b07af8b340b3bcd79b7758f5ac26

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Akademický článek

3-Phosphoinositide-Dependent Kinase 1 Controls Breast Tumor Growth in a Kinase-Dependent but Akt-Independent Manner

Autor: Paolo Armando Gagliardi, Laura di Blasio, Francesca Orso, Giorgio Seano, Roberto Sessa, Daniela Taverna, Federico Bussolino, Luca Primo

Publikováno v: Neoplasia: An International Journal for Oncology Research, Vol 14, Iss 8, Pp 719-731 (2012)

3-Phosphoinositide-dependent protein kinase 1 (PDK1) is the pivotal element of the phosphatidylinositol 3 kinase (PI3K) signaling pathway because it phosphorylates Akt/PKB through interactions with phosphatidylinositol 3,4,5 phosphate. Recent data in

Externí odkaz: https://doaj.org/article/ecd339830bd342668694a2a91a45c142

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Data from Increased Expression of α6 Integrin in Endothelial Cells Unveils a Proangiogenic Role for Basement Membrane

Autor: Federico Bussolino, Laura di Blasio, Enrico Giraudo, Marianna Martinelli, Roberto Sessa, Paolo Armando Gagliardi, Federica Maione, Cristina Roca, Giorgio Seano, Luca Primo

The integrin α6 subunit is part of the α6β1 and α6β4 integrin complexes, which are known to be receptors for laminins and to mediate several biological activities such as embryogenesis, organogenesis, and invasion of carcinoma cells. However, th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7aabe97a51de5bb7dc5a1fa0e7c1bbf7
https://doi.org/10.1158/0008-5472.c.6500243.v1

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Collective directional migration drives the formation of heteroclonal cancer cell clusters

Autor: Miriam Palmiero, Laura Di Blasio, Valentina Monica, Barbara Peracino, Luca Primo, Alberto Puliafito

Metastasisation occurs through the acquisition of invasive and survival capabilities that allow tumour cells to colonise distant sites. While the role of multicellular aggregates in cancer dissemination is acknowledged, the mechanisms that drive the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2c5ba4b99533359ec1284849c1a7fc45
https://doi.org/10.1101/2022.05.18.492411

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