Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Laura de Cubas"'
Autor:
Montserrat Vega, David Castillo, Laura de Cubas, Yirong Wang, Ying Huang, Elena Hidalgo, Margarita Cabrera
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-18 (2022)
Abstract Background In many organisms, aging is characterized by a loss of mitochondrial homeostasis. Multiple factors such as respiratory metabolism, mitochondrial fusion/fission, or mitophagy have been linked to cell longevity, but the exact impact
Externí odkaz:
https://doaj.org/article/1f2e0db6cab3415980ae66b1c2f67942
Autor:
Jarmila Princová, Clàudia Salat-Canela, Petr Daněk, Anna Marešová, Laura de Cubas, Jürg Bähler, José Ayté, Elena Hidalgo, Martin Převorovský
Publikováno v:
PLoS Genetics, Vol 19, Iss 1, p e1010582 (2023)
Oxidative stress is associated with cardiovascular and neurodegenerative diseases, diabetes, cancer, psychiatric disorders and aging. In order to counteract, eliminate and/or adapt to the sources of stress, cells possess elaborate stress-response mec
Externí odkaz:
https://doaj.org/article/6b3f0849a4714c1bbcf92b9f304769a0
Autor:
Laura de Cubas, Jorge Mallor, Víctor Herrera-Fernández, José Ayté, Rubén Vicente, Elena Hidalgo
Publikováno v:
Antioxidants, Vol 12, Iss 3, p 706 (2023)
Intracellular hydrogen peroxide (H2O2) levels can oscillate from low, physiological concentrations, to intermediate, signaling ones, and can participate in toxic reactions when overcoming certain thresholds. Fluorescent protein-based reporters to mea
Externí odkaz:
https://doaj.org/article/ddb97ed7f79644bd8919147c056a2382
Autor:
Mercè Carmona, Laura de Cubas, Eric Bautista, Marta Moral-Blanch, Iria Medraño-Fernández, Roberto Sitia, Susanna Boronat, José Ayté, Elena Hidalgo
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Reliable methods of measuring intracellular H2O2 fluctuations are necessary to advance redox biology. Here the authors design a H2O2 sensor based on the fission yeast peroxiredoxin Tpx1 to sense nanomolar fluctuations of intracellular H2O2 in respons
Externí odkaz:
https://doaj.org/article/aafcb8e611bf4afab90ca09a171dc392
Publikováno v:
Antioxidants, Vol 10, Iss 5, p 731 (2021)
Fluorescent protein-based reporters used to measure intracellular H2O2 were developed to overcome the limitations of small permeable dyes. The two major families of genetically encoded redox reporters are the reduction-oxidation sensitive green fluor
Externí odkaz:
https://doaj.org/article/fc4379ff7cb547ea992299eb8df9510a
Autor:
Hidalgo, Laura de Cubas, Jorge Mallor, Víctor Herrera-Fernández, José Ayté, Rubén Vicente, Elena
Publikováno v:
Antioxidants; Volume 12; Issue 3; Pages: 706
Intracellular hydrogen peroxide (H2O2) levels can oscillate from low, physiological concentrations, to intermediate, signaling ones, and can participate in toxic reactions when overcoming certain thresholds. Fluorescent protein-based reporters to mea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::2b82b0c844988046e0d38ef60fdc6542
Publikováno v:
Free Radical Biology and Medicine. 201:3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::923b4b79501ad1510a83a85380205c1b
https://doi.org/10.1016/j.freeradbiomed.2023.03.038
https://doi.org/10.1016/j.freeradbiomed.2023.03.038
Autor:
José Ayté, Iria Medraño-Fernandez, Marta Moral-Blanch, Eric Bautista, Laura de Cubas, Susanna Boronat, Mercè Carmona, Roberto Sitia, Elena Hidalgo
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Recercat. Dipósit de la Recerca de Catalunya
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Recercat. Dipósit de la Recerca de Catalunya
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Genetically encoded probes monitoring H2O2 fluctuations in living organisms are key to decipher redox signaling events. Here we use a new probe, roGFP2-Tpx1.C169S, to monitor pre-toxic fluctuations of peroxides in fission yeast, where the concentrati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0784c976375d329e2468336bb4b94a8
https://doi.org/10.1038/s41467-019-12475-0
https://doi.org/10.1038/s41467-019-12475-0
Autor:
Mercè, Carmona, Laura, de Cubas, Eric, Bautista, Marta, Moral-Blanch, Iria, Medraño-Fernández, Roberto, Sitia, Susanna, Boronat, José, Ayté, Elena, Hidalgo
Publikováno v:
Nature Communications
Genetically encoded probes monitoring H2O2 fluctuations in living organisms are key to decipher redox signaling events. Here we use a new probe, roGFP2-Tpx1.C169S, to monitor pre-toxic fluctuations of peroxides in fission yeast, where the concentrati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8702084a0fc9cbfa14405b72c2e6fb7f
https://pubmed.ncbi.nlm.nih.gov/31586057
https://pubmed.ncbi.nlm.nih.gov/31586057