Zobrazeno 1 - 10 of 18 pro vyhledávání: '"Laura Zaragoza-Infante"'
1
Akademický článek
Evidence of somatic hypermutation in the antigen binding sites of patients with CLL harboring IGHV genes with 100% germline identity
Autor: Electra Sofou, Laura Zaragoza-Infante, Nikolaos Pechlivanis, Georgios Karakatsoulis, Sofia Notopoulou, Niki Stavroyianni, Fotis Psomopoulos, Elisavet Georgiou, Anne Langlois de Septenville, Frederic Davi, Andreas Agathangelidis, Anastasia Chatzidimitriou, Kostas Stamatopoulos
Publikováno v: Frontiers in Oncology, Vol 12 (2022)
Classification of patients with chronic lymphocytic leukemia (CLL) based on the somatic hypermutation (SHM) status of the clonotypic immunoglobulin heavy variable (IGHV) gene has established predictive and prognostic relevance. The SHM status is asse
Externí odkaz: https://doaj.org/article/046ece4274104acc9f974cea09ee0302
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2
Akademický článek
Understanding Monoclonal B Cell Lymphocytosis: An Interplay of Genetic and Microenvironmental Factors
Autor: Chrysi Galigalidou, Laura Zaragoza-Infante, Anastasia Iatrou, Anastasia Chatzidimitriou, Kostas Stamatopoulos, Andreas Agathangelidis
Publikováno v: Frontiers in Oncology, Vol 11 (2021)
The term monoclonal B-cell lymphocytosis (MBL) describes the presence of a clonal B cell population with a count of less than 5 × 109/L and no symptoms or signs of disease. Based on the B cell count, MBL is further classified into 2 distinct subtype
Externí odkaz: https://doaj.org/article/efa67e0fa42246998d881be6f07618f4
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3
Akademický článek
B Cell Receptor Immunogenetics in B Cell Lymphomas: Immunoglobulin Genes as Key to Ontogeny and Clinical Decision Making
Autor: Katerina Gemenetzi, Andreas Agathangelidis, Laura Zaragoza-Infante, Electra Sofou, Maria Papaioannou, Anastasia Chatzidimitriou, Kostas Stamatopoulos
Publikováno v: Frontiers in Oncology, Vol 10 (2020)
The clonotypic B cell receptor immunoglobulin (BcR IG) plays a seminal role in B cell lymphoma development and evolution. From a clinical perspective, this view is supported by the remarkable therapeutic efficacy of BcR signaling inhibitors, even amo
Externí odkaz: https://doaj.org/article/79bb17763f7b4446b4fbcc46fe7b625f
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5
IgIDivA: immunoglobulin intraclonal diversification analysis
Autor: Laura Zaragoza-Infante, Valentin Junet, Nikos Pechlivanis, Styliani-Christina Fragkouli, Serovpe Amprachamian, Triantafyllia Koletsa, Anastasia Chatzidimitriou, Maria Papaioannou, Kostas Stamatopoulos, Andreas Agathangelidis, Fotis Psomopoulos
Publikováno v: Briefings in Bioinformatics, bbac349
Intraclonal diversification (ID) within the immunoglobulin (IG) genes expressed by B cell clones arises due to ongoing somatic hypermutation (SHM) in a context of continuous interactions with antigen(s). Defining the nature and order of appearance of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e763dce0ca2c00bc7383e0181d5a714c
https://pubmed.ncbi.nlm.nih.gov/36044248
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6
Purpose-Built Immunoinformatics for BcR IG/TR Repertoire Data Analysis
Autor: Chrysi Galigalidou, Laura Zaragoza-Infante, Anastasia Chatzidimitriou, Kostas Stamatopoulos, Fotis Psomopoulos, Andreas Agathangelidis
Publikováno v: Methods Mol Biol
Methods in Molecular Biology ISBN: 9781071621141
The study of antigen receptor gene repertoires using next-generation sequencing (NGS) technologies has disclosed an unprecedented depth of complexity, requiring novel computational and analytical solutions. Several bioinformatics workflows have been
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b99e9fbf58d99cecd61c317d9e78954
https://europepmc.org/articles/PMC9761556/
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8
B Cell Receptor Immunogenetics in B Cell Lymphomas: Immunoglobulin Genes as Key to Ontogeny and Clinical Decision Making
Autor: Andreas Agathangelidis, Katerina Gemenetzi, Kostas Stamatopoulos, Anastasia Chatzidimitriou, Electra Sofou, Maria Papaioannou, Laura Zaragoza-Infante
Publikováno v: Frontiers in Oncology
Frontiers in Oncology, Vol 10 (2020)
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DOAJ-Articles
The clonotypic B cell receptor immunoglobulin (BcR IG) plays a seminal role in B cell lymphoma development and evolution. From a clinical perspective, this view is supported by the remarkable therapeutic efficacy of BcR signaling inhibitors, even amo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76bea005d382778b71d2a27b35fb3122
http://europepmc.org/articles/PMC7006488
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10
Dose dependent gene expression is dynamically modulated by the history, physiology and age of yeast cells
Autor: Daniel Poveda-Huertes, Amparo Pascual-Ahuir, Elena Vanacloig-Pedros, Eva González-Cantó, Markus Proft, Julia Pable, Sandra Saiz-Balbastre, Sonia Squeo, Pauline Juyoux, Alvaro Ureña-Marco, Laura Zaragoza-Infante
Publikováno v: RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
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Digital.CSIC. Repositorio Institucional del CSIC
15 páginas, 9 figuras.
Cells respond to external stimuli with transient gene expression changes in order to adapt to environmental alterations. However, the dose response profile of gene induction upon a given stress depends on many intrinsic a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::867e245db07ef6e2e1f29d52ef7f352e
http://hdl.handle.net/10251/154396
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