Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Laura Z Vanags"'
Autor:
Alex H P Chan, Richard P Tan, Praveesuda L Michael, Bob S L Lee, Laura Z Vanags, Martin K C Ng, Christina A Bursill, Steven G Wise
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0174773 (2017)
Current animal models for the evaluation of synthetic grafts are lacking many of the molecular tools and transgenic studies available to other branches of biology. A mouse model of vascular grafting would allow for the study of molecular mechanisms o
Externí odkaz:
https://doaj.org/article/1140067a143145319250df802d6e349c
Autor:
Dhanya Ravindran, Anisyah Ridiandries, Laura Z Vanags, Rodney Henriquez, Siân Cartland, Joanne T M Tan, Christina A Bursill
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0173224 (2017)
Chemokines are important in macrophage recruitment and the progression of atherosclerosis. The 'M3' chemokine binding protein inactivates key chemokines involved in atherosclerosis (e.g. CCL2, CCL5 and CX3CL1). We aimed to determine the effect of M3
Externí odkaz:
https://doaj.org/article/af89377ab6d54a9d893736137e15f008
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 38:1691-1701
Revascularization because of coronary artery disease is commonly achieved by percutaneous coronary intervention with stent deployment. Refinement in interventional techniques, major improvements in stent design (particularly drug-eluting stents), and
Autor:
Andrew J. Murphy, Andreas Schaefer, Ziad A. Ali, Keyvan Karimi Galougahi, Laura Z. Vanags, Christina A. Bursill, Steven G. Wise, Joanne T.M. Tan
Publikováno v:
JACC: Basic to Translational Science
JACC: Basic to Translational Science, Vol 3, Iss 2, Pp 200-209 (2018)
JACC: Basic to Translational Science, Vol 3, Iss 2, Pp 200-209 (2018)
Visual Abstract
Highlights • This study shows that apoA-I may be an alternative strategy to improve the biocompatibility of stents. • Systemic infusions of apoA-I reduce in-stent neointimal hyperplasia in a murine model of stenting. • The
Highlights • This study shows that apoA-I may be an alternative strategy to improve the biocompatibility of stents. • Systemic infusions of apoA-I reduce in-stent neointimal hyperplasia in a murine model of stenting. • The
Autor:
Kwong Man Ng, Jamie Morton, Joanne T.M. Tan, Laura Z. Vanags, Anisyah Ridiandries, David S. Celermajer, Tania Tsatralis, Shisan Bao, Chung-Wah Siu, Martin K.C. Ng, Christina A. Bursill
Publikováno v:
JACC: Basic to Translational Science, Vol 3, Iss 2, Pp 187-199 (2018)
JACC: Basic to Translational Science
JACC: Basic to Translational Science
Visual Abstract
Highlights • The atheroprotective effects of apoA-I are dependent on the plaque stage from which apoA-I is infused. • The atheroprotective effects of apoA-I infusions are also impaired in older mice with a greater disease mil
Highlights • The atheroprotective effects of apoA-I are dependent on the plaque stage from which apoA-I is infused. • The atheroprotective effects of apoA-I infusions are also impaired in older mice with a greater disease mil
Autor:
Ziad A. Ali, Marcela M.M. Bilek, Laura Z. Vanags, Joanne T.M. Tan, Praveesuda S. Michael, Steven G. Wise, Christina A. Bursill, Miguel Santos
Publikováno v:
Nanomedicine: Nanotechnology, Biology and Medicine. 13:2141-2150
We utilized a plasma activated coating (PAC) to covalently bind the active component of high density lipoproteins (HDL), apolipoprotein (apo) A-I, to stainless steel (SS) surfaces. ApoA-I suppresses restenosis and thrombosis and may therefore improve
Autor:
Laura Lecce, Yuen Ting Lam, Zoe E. Clayton, Stacy Robertson, Tania Tsatralis, David S. Celermajer, Sui Ching G. Yuen, Joanne T.M. Tan, Louise L. Dunn, Martin K.C. Ng, Hamish C. G. Prosser, Christina A. Bursill, Anisyah Ridiandries, Laura Z. Vanags
Publikováno v:
Diabetes. 65:3091-3103
Disordered neovascularization and impaired wound healing are important contributors to diabetic vascular complications. We recently showed that high-density lipoproteins (HDLs) enhance ischemia-mediated neovascularization, and mounting evidence sugge
Autor:
Christina A. Bursill, Benjamin M. Weimann, Zoe E. Clayton, Anisyah Ridiandries, Stacy Robertson, Joanne T.M. Tan, Tania Tsatralis, Laura Z. Vanags, Martin K.C. Ng, Emma L. Solly, Jennifer Q. J. Zhang, Samuel T. Hourigan, Edward R. Tepper, Victoria A. Nankivell, Rodney Henriquez, Stephen J. Nicholls
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Diabetic vascular complications are associated with impaired ischaemia-driven angiogenesis. We recently found that reconstituted high-density lipoproteins (rHDL) rescue diabetes-impaired angiogenesis. microRNAs (miRNAs) regulate angiogenesis and are
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology. 38(8)
Revascularization because of coronary artery disease is commonly achieved by percutaneous coronary intervention with stent deployment. Refinement in interventional techniques, major improvements in stent design (particularly drug-eluting stents), and
Autor:
Nathan K P, Wong, Helena, Cheung, Emma L, Solly, Laura Z, Vanags, William, Ritchie, Stephen J, Nicholls, Martin K C, Ng, Christina A, Bursill, Joanne T M, Tan
Publikováno v:
International Journal of Molecular Sciences
Angiogenesis, the process of forming new blood vessels, is crucial in the physiological response to ischemia, though it can be detrimental as part of inflammation and tumorigenesis. We have previously shown that high-density lipoproteins (HDL) modula