Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Laura Y. Kim"'
Autor:
Laura Y. Kim, William J. Rice, Edward T. Eng, Mykhailo Kopylov, Anchi Cheng, Ashleigh M. Raczkowski, Kelsey D. Jordan, Daija Bobe, Clinton S. Potter, Bridget Carragher
Publikováno v:
Frontiers in Molecular Biosciences, Vol 5 (2018)
Cryo electron microscopy facilities running multiple instruments and serving users with varying skill levels need a robust and reliable method for benchmarking both the hardware and software components of their single particle analysis workflow. The
Externí odkaz:
https://doaj.org/article/6aa7a9a89779493995198451bdcb91a6
Autor:
Laura Y. Kim, Clarence Yu Cheng, Paul V. Ruijgrok, Rhiju Das, Gregory M. Alushin, Zev Bryant, Tosan Omabegho, Pinar S. Gurel
Publikováno v:
Nature nanotechnology
Engineering biomolecular motors can provide direct tests of structure-function relationships and customized components for controlling molecular transport in artificial systems or in living cells. In previous work, synthetic nucleic acid motors have
Autor:
Mihir Pershad, Sharon L. Campbell, Peter M. Thompson, Hyunna T. Lee, Laura Y. Kim, Gregory M. Alushin
Publikováno v:
Journal of Molecular Biology. 428:10-25
Vinculin is an essential adhesion protein that links membrane-bound integrin and cadherin receptors through their intracellular binding partners to filamentous actin, facilitating mechanotransduction. Here we present an 8.5-Å-resolution cryo-electro
Autor:
William J. Rice, Clinton S. Potter, Lambertus Alink, Kelsey D. Jordan, Anchi Cheng, Bridget Carragher, Edward T. Eng, Laura Y. Kim
Automated data acquisition is used widely for single-particle reconstruction of three-dimensional (3D) volumes of biological complexes preserved in vitreous ice and imaged in a transmission electron microscope. Automation has become integral to this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51964de276a4cbd7469613dd61b065f1
https://europepmc.org/articles/PMC6163078/
https://europepmc.org/articles/PMC6163078/
Autor:
Anchi Cheng, Bridget Carragher, Daija Bobe, Edward T. Eng, William J. Rice, Clinton S. Potter, Laura Y. Kim, Kelsey D. Jordan, Ashleigh M. Raczkowski, Mykhailo Kopylov
Publikováno v:
Frontiers in Molecular Biosciences
Frontiers in Molecular Biosciences, Vol 5 (2018)
Frontiers in Molecular Biosciences, Vol 5 (2018)
Cryo electron microscopy facilities running multiple instruments and serving users with varying skill levels need a robust and reliable method for benchmarking both the hardware and software components of their single particle analysis workflow. The
Autor:
Peter D. Kwong, William J. Rice, Clinton S. Potter, Lawrence Shapiro, Anchi Cheng, Priyamvada Acharya, Venkata P. Dandey, Hui Wei, Micah Rapp, Alex J. Noble, Giovanna Scapin, David Jeruzalmi, Jillian Chase, Amedee des Georges, Zhening Zhang, Laura Y. Kim, Yong Zi Tan, Julia Brasch, Bridget Carragher, Edward T. Eng, Carl J. Negro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6a6080d901c5fd558c4ab8ef778853c
https://doi.org/10.7554/elife.34257.121
https://doi.org/10.7554/elife.34257.121
Autor:
Bridget Carragher, William J. Rice, Clinton S. Potter, Edward T. Eng, Anchi Cheng, Alex J. Noble, Laura Y. Kim
Recent advances in instrumentation and automation have made cryo-EM a popular method for producing near-atomic resolution structures of a variety of proteins and complexes. Sample preparation is still a limiting factor in collecting high quality data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8b6603aa6626799f0cf9d7db991aa08
https://doi.org/10.1101/302018
https://doi.org/10.1101/302018
Autor:
William J. Rice, Clinton S. Potter, Laura Y. Kim, Daija Bobe, Bridget Carragher, Mykhailo Kopylov, Edward T. Eng, Ashleigh M. Raczkowski
Publikováno v:
Biophysical Journal. 116:572a-573a
Autor:
Laura Y. Kim, Bridget Carragher, Edward T. Eng, Anchi Cheng, Giovanna Scapin, Lawrence Shapiro, Priyamvada Acharya, Julia Brasch, Alex J. Noble, Amedee des Georges, Venkata P. Dandey, Hui Wei, Micah Rapp, Carl J. Negro, Jillian Chase, Yong Zi Tan, William J. Rice, Zhening Zhang, Clinton S. Potter, David Jeruzalmi, Peter D. Kwong
Publikováno v:
eLife
eLife, Vol 7 (2018)
eLife, Vol 7 (2018)
Single particle cryo-electron microscopy (cryoEM) is often performed under the assumption that particles are freely floating away from the air-water interfaces and in thin, vitreous ice. In this study, we performed fiducial-less tomography on over 50
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0cc4ab1ee8487a8b3838dc3f393e2e1
Autor:
Laura Y. Kim, Paul V. Ruijgrok, Zev Bryant, Tosan Omabegho, Pinar S. Gurel, Gregory M. Alushin
Publikováno v:
eLife
eLife, Vol 6 (2017)
eLife, Vol 6 (2017)
Despite extensive scrutiny of the myosin superfamily, the lack of high-resolution structures of actin-bound states has prevented a complete description of its mechanochemical cycle and limited insight into how sequence and structural diversification