Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Laura Weßling"'
Autor:
Ilona Hagelstein, Laura Wessling, Alexander Rochwarger, Latifa Zekri, Boris Klimovich, Christian M. Tegeler, Gundram Jung, Christian M. Schürch, Helmut R. Salih, Martina S. Lutz
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Background Breast cancer (BC) is the most common malignancy in women. Immunotherapy has revolutionized treatment options in many malignancies, and the introduction of immune checkpoint inhibition yielded beneficial results also in BC. Howeve
Externí odkaz:
https://doaj.org/article/4fe2b27d65564a37932f57ac8d6d6e06
Autor:
Ilona Hagelstein, Gundram Jung, Helmut R Salih, Latifa Zekri, Martina S Lutz, Laura Weßling, Christian M Tegeler
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/bf5eb3c2eb8e4c64ad07901d9dce6651
Autor:
Marcel Wacker, Jens Bauer, Laura Wessling, Marissa Dubbelaar, Annika Nelde, Hans-Georg Rammensee, Juliane S. Walz
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionMass spectrometry-based immunopeptidomics is the only unbiased method to identify naturally presented HLA ligands, which is an indispensable prerequisite for characterizing novel tumor antigens for immunotherapeutic approaches. In recent
Externí odkaz:
https://doaj.org/article/d4f482ce7c9940ef86b60d3f8613f612
Autor:
Martina S. Lutz, Latifa Zekri, Laura Weßling, Susanne Berchtold, Jonas S. Heitmann, Ulrich M. Lauer, Gundram Jung, Helmut R. Salih
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
T cell-based immunotherapy has significantly improved treatment options for many malignancies. However, despite these and other therapeutic improvements over the last decades, gastrointestinal cancers, in particular pancreatic, hepatic and gastric ca
Externí odkaz:
https://doaj.org/article/a9c1d07ea6db491a89f09555d59e60dd
Autor:
Peter Kubiniok, Ana Marcu, Leon Bichmann, Leon Kuchenbecker, Heiko Schuster, David J. Hamelin, Jérôme D. Duquette, Kevin A. Kovalchik, Laura Wessling, Oliver Kohlbacher, Hans-Georg Rammensee, Marian C. Neidert, Isabelle Sirois, Etienne Caron
Publikováno v:
iScience, Vol 25, Iss 2, Pp 103768- (2022)
Summary: Understanding the molecular principles that govern the composition of the MHC-I immunopeptidome across different primary tissues is fundamentally important to predict how T cells respond in different contexts in vivo. Here, we performed a gl
Externí odkaz:
https://doaj.org/article/01cf40cfe26443af9d7dfabf83c86350
Autor:
Eric Bonneil, Qing Ma, Lukas Reiter, Isabelle Sirois, Joel Lanoix, Etienne Caron, Roland Bruderer, Pierre Thibault, Laura Wessling, David Hamelin, Pouya Faridi, Jerome Despault, Frederic Saab, Eustache Paramithiotis, Chen Li, Mathieu Courcelles, Anthony W. Purcell, Anne Jang, Peter Kubiniok, Kevin A. Kovalchik, Marco Tognetti
Publikováno v:
Molecular & Cellular Proteomics : MCP
MS-based immunopeptidomics is maturing into an automatized and high-throughput technology, producing small- to large-scale datasets of clinically relevant major histocompatibility complex (MHC) class I-associated and class II-associated peptides. Con
Autor:
Eric Bonneil, Joel Lanoix, Anthony W. Purcell, Isabelle Sirois, Roland Bruderer, Marco Tognetti, Qing Ma, Frederic Saab, Kevin A. Kovalchik, Pouya Faridi, Lukas Reiter, Peter Kubiniok, Jerome Despault, Chen Li, Mathieu Courcelles, Etienne Caron, David Hamelin, Pierre Thibault, Laura Wessling
Immunopeptidomics refers to the science of investigating the composition and dynamics of peptides presented by major histocompatibility complex (MHC) class I and class II molecules using mass spectrometry (MS). Here, we aim to provide a technical rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3eb79c58cac76da3025b9c2e33ecbf83
https://doi.org/10.1101/2020.11.02.360958
https://doi.org/10.1101/2020.11.02.360958
Autor:
Ana Marcu, Kevin A. Kovalchik, Hans-Georg Rammensee, Etienne Caron, Oliver Kohlbacher, Laura Wessling, David Hamelin, Jerome Despault, Heiko Schuster, Peter Kubiniok, Stefan Stevanovic, Marian Christoph Neidert, Leon Kuchenbecker, Leon Bichmann, Isabelle Sirois
Understanding the molecular principles that govern the composition of the mammalian MHC-I immunopeptidome (MHC-Ii) across different primary tissues is fundamentally important to predict how T cell respond in different contextsin vivo. Here, we perfor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f6687904fe3de270da94807ccaf0e61
https://doi.org/10.1101/2020.09.28.317750
https://doi.org/10.1101/2020.09.28.317750