Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Laura W Engstrom"'
Autor:
Cristina St Pierre, Jane Guo, John D Shin, Laura W Engstrom, Hyun-Hee Lee, Alan Herbert, Laura Surdi, James Baker, Michael Salmon, Sanjiv Shah, J Michael Ellis, Hani Houshyar, Michael A Crackower, Melanie A Kleinschek, Dallas C Jones, Alexandra Hicks, Dennis M Zaller, Stephen E Alves, Ravisankar A Ramadas
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0180870 (2017)
While the immune system is essential for the maintenance of the homeostasis, health and survival of humans, aberrant immune responses can lead to chronic inflammatory and autoimmune disorders. Pharmacological modulation of drug targets in the immune
Externí odkaz:
https://doaj.org/article/a511e5553a1e4c19982a055d21745012
Autor:
Daniel Lundell, Laura W. Engstrom, Loretta A. Bober, James V. Jackson, Jay S. Fine, Alberto Rojas-Triana, Gregory Deno
Publikováno v:
Inflammation. 27:161-174
We have characterized leukocyte migration to the pleural cavity in a methylated-BSA (mBSA)-induced model of murine delayed-type hypersensitivity and evaluated the ability of IL-4 and IL-10 to modulate this response. Neutrophils, macrophages, T cells,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aaa5be6adb4c1b0d91b83190e29fc436
https://doi.org/10.1023/a:1025076111950
https://doi.org/10.1023/a:1025076111950
Publikováno v:
Blood. 98:3456-3464
Treatment of leukemia by myeloablative conditioning and transplantation of major histocompatibility complex (MHC)–mismatched stem cells is generally avoided because of the high risk of graft rejection or lethal graft-versus-host disease (GVHD). Thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0035707592d14e97eda607e230fb08d5
https://doi.org/10.1182/blood.v98.12.3456
https://doi.org/10.1182/blood.v98.12.3456
Autor:
Leo Luznik, Ephraim J. Fuchs, Frederic B. Askin, Sherrie L. Tennessee, Lori Noffsinger, Laura W. Engstrom, James F. Casella, Thomas S. Kickler, Steven N. Goodman, Robert Iannone, Constance A. Griffin, Anita L. Hawkins
Publikováno v:
Blood. 97:3960-3965
Sickle cell anemia (SCA) is an inherited disorder of beta-globin, resulting in red blood cell rigidity, anemia, painful crises, organ infarctions, and reduced life expectancy. Allogeneic blood or marrow transplantation (BMT) can cure SCA but is assoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7aba1833a1ae55a88cd0929c683d3046
https://doi.org/10.1182/blood.v97.12.3960
https://doi.org/10.1182/blood.v97.12.3960
Autor:
Alberto Rojas-Triana, James V. Jackson, Denise Manfra, Jay S. Fine, Long Cui, Laura W. Engstrom, Daniel Lundell, David Kinsley, Timothy J. Kowalski, Ying Li, Maureen Laverty, Eric L. Gustafson, Michaela C. Stanton, Loretta A. Bober, Shu-Cheng Chen, Chung-Her Jenh
Publikováno v:
PPAR Research, Vol 2010 (2010)
PPAR Research
PPAR Research
The kinetics of metabolic and inflammatory parameters associated with obesity were evaluated in a murine diet-induced obesity (DIO) model using a diet high in fat and cholesterol. Cellular infiltration and mediator production were assessed and shown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc2e2212981aad5357ad60de410c787b
https://doaj.org/article/cae9bc5d7d7f4e2ba1dbbdd988dcff99
https://doaj.org/article/cae9bc5d7d7f4e2ba1dbbdd988dcff99
Autor:
Katsuhiro Mihara, Jay S. Fine, Ying Li, David Kinsley, Laura W. Engstrom, Rob Nelissen, M. Consuelo Pinzon-Ortiz, Shu-Cheng Chen, Denise Manfra
Publikováno v:
International immunopharmacology. 9(10)
Molecular and cellular assessment of dermal delayed-type hypersensitivity (DTH) responses is a useful approach for evaluating the mechanism of action (MOA) of immunomodulatory agents. In the present report, we characterized the delayed-type hypersens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3218ec1f5d77578bf585c4cead20d583
https://pubmed.ncbi.nlm.nih.gov/19616132
https://pubmed.ncbi.nlm.nih.gov/19616132
Autor:
Eric M. Parker, Maria Pinzon-Ortiz, Hubert B. Josien, Laura W. Engstrom, Gwendolyn T. Wong, Hu-Jung J. Lee, Lili Zhang, Jay S. Fine, Frederique M. Poulet, Qi Zhang, Thomas A. Bara, Guy A. Higgins, Denise Manfra
Publikováno v:
The Journal of biological chemistry. 279(13)
Inhibition of gamma-secretase, one of the enzymes responsible for the cleavage of the amyloid precursor protein (APP) to produce the pathogenic beta-amyloid (Abeta) peptides, is an attractive approach to the treatment of Alzheimer disease. In additio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::805624b9692a5fcc38070efe53c1e9ab
https://pubmed.ncbi.nlm.nih.gov/14709552
https://pubmed.ncbi.nlm.nih.gov/14709552
Autor:
Jay S, Fine, Alberto, Rojas-Triana, James V, Jackson, Laura W, Engstrom, Gregory S, Deno, Daniel J, Lundell, Loretta A, Bober
Publikováno v:
Inflammation. 27(4)
We have characterized leukocyte migration to the pleural cavity in a methylated-BSA (mBSA)-induced model of murine delayed-type hypersensitivity and evaluated the ability of IL-4 and IL-10 to modulate this response. Neutrophils, macrophages, T cells,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fc28e3de84d928b6e73d0c78a7a9eee9
https://pubmed.ncbi.nlm.nih.gov/14527170
https://pubmed.ncbi.nlm.nih.gov/14527170
Publikováno v:
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 8(3)
Cyclophosphamide (Cy) has been studied extensively for its immunosuppressive properties and is frequently combined with total body irradiation (TBI) as conditioning prior to HLA-identical allogeneic blood or marrow transplantation (alloBMT) in humans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdf61dd0b2787dbf8653715247762422
https://pubmed.ncbi.nlm.nih.gov/11939602
https://pubmed.ncbi.nlm.nih.gov/11939602
Autor:
Atul Bedi, Céline Gélinas, Laura W. Engstrom, Qinwen Zeng, Ephraim J. Fuchs, Bijoyesh Mookerjee, Gauri. C. Bedi, Rajani Ravi
Publikováno v:
Nature cell biology. 3(4)
TRAIL (tumour-necrosis factor-related apoptosis ligand or Apo2L) triggers apoptosis through engagement of the death receptors TRAIL-R1 (also known as DR4) and TRAIL-R2 (DR5). Here we show that the c-Rel subunit of the transcription factor NF-kappaB i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d767c825a34582184f0371d700436891
https://pubmed.ncbi.nlm.nih.gov/11283615
https://pubmed.ncbi.nlm.nih.gov/11283615