Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Laura Vela-Martín"'
Autor:
Antonio Lahera, Laura Vela-Martín, Pablo Fernández-Navarro, Pilar Llamas, José L. López-Lorenzo, Javier Cornago, Javier Santos, José Fernández-Piqueras, María Villa-Morales
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-13 (2024)
Abstract Precursor T-cell neoplasms (T-ALL/LBL) are aggressive hematological malignancies that arise from the malignant transformation of immature thymocytes. Despite the JAK/STAT pathway is recurrently altered in these neoplasms, there are not pharm
Externí odkaz:
https://doaj.org/article/c8037d4ae28942409f7da1cc7c6cb1b9
Autor:
Antonio Lahera, Pilar López‐Nieva, Hernán Alarcón, José L. Marín‐Rubio, María Á. Cobos‐Fernández, Pablo Fernández‐Navarro, Agustín F. Fernández, Laura Vela‐Martín, Isabel Sastre, Sara Ruiz‐García, Pilar Llamas, José L. López‐Lorenzo, Javier Cornago, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales
Publikováno v:
Scopus
Despite the Janus kinase/signal transducers and activators of transcription (JAK/STAT) pathway being frequently altered in T-ALL/LBL, no specific therapy has been approved for T-ALL/LBL patients with constitutive signalling by JAK/STAT, so there is a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f71d0f2b00cba28da6de3f3d19757bf6
https://doi.org/10.1111/bjh.18694
https://doi.org/10.1111/bjh.18694
Autor:
José Luis Marín-Rubio, Laura Vela-Martín, Jack Gudgeon, Eduardo Pérez-Gómez, Frances R. Sidgwick, Matthias Trost, Debbie L. Cunningham, Javier Santos, José Fernández-Piqueras, María Villa-Morales
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 23; Pages: 15157
A reduction in FADD levels has been reported in precursor T-cell neoplasms and other tumor types. Such reduction would impact on the ability of tumor cells to undergo apoptosis and has been associated with poor clinical outcomes. However, FADD is als
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86dc15180195a2cd73bf1906987520a8
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Cancers
Cancers, Vol 11, Iss 10, p 1462 (2019)
instname
Cancers
Cancers, Vol 11, Iss 10, p 1462 (2019)
FADD was initially described as an adaptor molecule for death receptor-mediated apoptosis, but subsequently it has been implicated in nonapoptotic cellular processes such as proliferation and cell cycle control. During the last decade, FADD has been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9792b41daea14bda2290c6ee47782f6
https://doi.org/10.3390/cancers11101462
https://doi.org/10.3390/cancers11101462