Výsledky vyhledávání - "Laura Vargiu"

Isolation ofJuniperus phoeniceaVolatiles by Supercritical Carbon Dioxide Extraction and Bioactivity Assays

Autor: Alessandra Cadeddu, Silvia Porcedda, Valeria Mascia, Laura Vargiu, Roberta Loddo, Alessandra Caredda, Bruno Marongiu, Alessandra Piras

Publikováno v: Journal of Essential Oil Research. 16:256-261

By means of a supercritical fluid extractor, extract of Juniperus phoenicea L. was obtained in a single extraction stage. The yield was 0.2% by mass. The operative conditions were: extractor, pressure, P = 90 bar and temperature, T = 50°C; first sep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d0518abacfd7709b4d7ddc3420beb85b
https://doi.org/10.1080/10412905.2004.9698715

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Design, Synthesis, SAR, and Molecular Modeling Studies of Acylthiocarbamates: A Novel Series of Potent Non-nucleoside HIV-1 Reverse Transcriptase Inhibitors Structurally Related to Phenethylthiazolylthiourea Derivatives

Autor: Tiziana Marceddu, Paolo La Colla, Alessandra Pani, O. Bruno, Silvia Schenone, Francesco Bondavalli, Andrea Spallarossa, Angelo Ranise, Massimo Mura, Laura Vargiu

Publikováno v: Journal of Medicinal Chemistry. 46:768-781

A novel series of potent, selective HIV-1 N-acylthiocarbamate (ATC) nonnucleoside reverse transcriptase inhibitors (NNRTIs) is described. The title compounds were synthesized through a highly convergent, one-pot procedure. In cell-based assays, the l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30ea4de4db6b9670b1fcefc5bb11f1cc
https://doi.org/10.1021/jm0209984

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Synthesis and antiproliferative activity of 3-aryl-2-(1H-benzotriazol-1-yl)acrylonitriles. Part III

Autor: Massimiliano La Colla, Antonio Carta, Michele Francesco Luigi Palomba, Roberta Loddo, Laura Vargiu, Paolo Sanna

Publikováno v: European Journal of Medicinal Chemistry. 37:891-900

A new series of 30 3-aryl-2-(1H-benzotriazol-1-yl)acrylonitriles were synthesized and tested for biological activity as part of our research in the antimicrobial and antitumor fields. In particular, title compounds were evaluated in vitro against rep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8fd50be5d21a952611c8f9315c887d7
https://doi.org/10.1016/s0223-5234(02)01411-3

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ChemInform Abstract: Disoxaril-Related 3-(Diethylamino)-5-phenylisoxazoles

Autor: Bernardetta Ledda, Francesca Demontis, Laura Vargiu, Mauro Mazzei, Ramona Dondero

Publikováno v: ChemInform. 31

Previous research has shown that 3-(dialkylamino)-5-phenylisoxazoles possessing a compact structure were active against HRV-2 and, consequently, presented a type B activity. In this paper, 3-(diethylamino)-5-phenylisoxazoles, which are structurally m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::04c93f5f6787c3f73e6a85d922d98f1d
https://doi.org/10.1002/chin.200028127

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ChemInform Abstract: Synthesis and anti-HIV-1 Activity of New Delavirdine Analogues Carrying Arylpyrrole Moieties

Autor: Giovanni Loriga, Gabriele Murineddu, Gérard Aimé Pinna, Paolo La Colla, Chiara Murgioni, Giuseppe Enrico Grella, Laura Vargiu, Massimo Mura

Publikováno v: ChemInform. 33

In our search for novel anti-human immunodeficiency virus (HIV)-1 agents, 14 delavirdine analogues were synthesized and evaluated as potential anti-HIV-1 agents in cell-based assays. Compound 1Aa exhibited potent and selective anti-HIV-1 activity in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2d7ab45633c1c130f81e949efb8d8820
https://doi.org/10.1002/chin.200219147

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Novel indolyl aryl sulfones active against HIV-1 carrying NNRTI resistance mutations: synthesis and SAR studies

Autor: Giuseppe La Regina, Romano Silvestri, Laura Vargiu, Paolo La Colla, Silvio Massa, Tiziana Marceddu, Massimo Mura, Marino Artico, Gabriella De Martino, Anna Giulia Loi

Publikováno v: Journal of medicinal chemistry. 46(12)

The potent anti-HIV-1 activities of L-737,126 (2) and PAS sulfones prompted us to design and test against HIV-1 in acutely infected MT-4 cells a number of novel 1- and 3-benzenesulfonylindoles. Indoles belonging to the 1-benzenesulfonyl series were f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69da161d7e29b09f0df479fd5512228a
https://pubmed.ncbi.nlm.nih.gov/12773052

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1,5-Benzodiazepines. Part XII. Synthesis and biological evaluation of tricyclic and tetracyclic 1,5-benzodiazepines derivatives as nevirapine analogues

Autor: Maria Elena Marongiu, Laura Vargiu, Mario Di Braccio, Giorgio Roma, Giancarlo Grossi, Massimo Mura

A number of properly substituted 5H-pyrimido[4,5-b][1,5]benzodiazepines (2) and pyrazolo[3,4-b][1,5]benzodiazepines (3 and 4), as well as compounds 5-7, which are derivatives of new tetracyclic systems, were prepared as nevirapine analogues through m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3314809ce1d4257f6a970f76d74ef32
http://hdl.handle.net/11567/779392

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