Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Laura V. Hale"'
Publikováno v:
Journal of Bone and Mineral Research. 1:489-495
The effects of three vitamin D3 metabolites, 25-hydroxyvitamin D3 (25-(OH)D3), 1 alpha,25-dihydroxyvitamin D3 (1 alpha, 25-(OH)2D3), and 24R,25-dihydroxyvitamin D3 (24R,25-(OH)2D3) on the activity of alkaline phosphatase (AP), a key enzyme involved i
Autor:
R.L. Cain, Charles A. Frolik, Andrew G. Geiser, Masahiko Sato, Allen Schmidt, Anita K. Harvey, Xuhao Yang, Yanfei L. Ma, Qingqiang Zeng, Juha Risteli, Laura V. Hale, R.J. Sells Galvin
Publikováno v:
Bone. 40:1103-1109
Serum PINP has emerged as a reliable marker of bone turnover in humans and is routinely used to monitor bone formation. However, the effects of PTH (1-34) on bone turnover have not been evaluated following short-term treatment. We present data demons
Autor:
N.H. Kulkarni, P.G. Mitchell, T. Hu, Xi Lin, Leah M. Helvering, Yanfei L. Ma, Anita K. Harvey, R.L. Cain, Tao Wei, Rebecca R. Miles, D.D. Edmondson, J.L. Oskins, Laura V. Hale, T.P. Ryan, Jude E. Onyia, Qingqiang Zeng, Mark Chambers, M.A. Carozza, C. Lin, Frank Lawrence
Publikováno v:
Osteoarthritis and cartilage. 18(7)
Objective The purpose of this study was to use microarray technology to: (1) understand the early molecular events underlying the damage of articular cartilage initiated by this surgical procedure, and (2) determine whether these changes mimic those
Autor:
Kristen M, Borchert, Rachelle J, Sells Galvin, Laura V, Hale, O Joseph, Trask, Debra R, Nickischer, Keith A, Houck
Publikováno v:
Methods in enzymology. 414
Development of means to screen primary human cells rather than established cell lines is important in improving the predictive value of cellular assays in drug discovery. We describe a method of using automated fluorescent microscopy to detect activa
Autor:
Laura V. Hale, Debra Nickischer, Keith A. Houck, O. Joseph Trask, Rachelle J. Sells Galvin, Kristen M. Borchert
Development of means to screen primary human cells rather than established cell lines is important in improving the predictive value of cellular assays in drug discovery. We describe a method of using automated fluorescent microscopy to detect activa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87a0d2a502c034a7a2d9940d91de873b
https://doi.org/10.1016/s0076-6879(06)14009-4
https://doi.org/10.1016/s0076-6879(06)14009-4
Autor:
Keith A. Houck, Debra Nickischer, Robin J. Gonyier, Kristen M. Borchert, Laura V. Hale, O. Joseph Trask, Rachelle J. Sells Galvin, David L. Halladay, Charles A. Frolik
Publikováno v:
Assay and drug development technologies. 3(2)
We have developed a high-content screening (HCS) assay to find activators of Wnt/Frizzled (Wnt/Fzd), a pathway known to be important in bone formation. Utilizing primary human preosteoblasts as a model, activation of the Wnt/Fzd pathway was detected
Autor:
Bomie Han, Marci Copeland, Andrew G. Geiser, Laura V. Hale, Anita Harvey, Yanfei L. Ma, Connie S. Powers, Masahiko Sato, Jinsam You, John E. Hale
Publikováno v:
Journal of Proteome Research; Nov2007, Vol. 6 Issue 11, p4218-4229, 12p
Autor:
Kristen M. Borchert, Rachelle J. Sells Galvin, Charles A. Frolik, Laura V. Hale, David L. Halladay, Robin J. Gonyier, O. Joseph Trask, Debra R. Nickischer, Keith A. Houck
Publikováno v:
Assay & Drug Development Technologies; Apr2005, Vol. 3 Issue 2, p133-141, 9p
Publikováno v:
In Vitro Cellular & Developmental Biology. 22:597-603
A serum-free medium for postembryonic chicken epiphyseal growth plate chondrocytes has been developed from 104 MCDB medium. To enable these fastidious cells to survive, grow, and express normal phenotype, a substantial increase over MCDB 104 in the l