Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Laura V, Gonzalez Bosc"'
Autor:
Selina M. Garcia, Tracy R. Yellowhair, Neil D. Detweiler, Rosstin Ahmadian, Lindsay M. Herbert, Laura V. Gonzalez Bosc, Thomas C. Resta, Nikki L. Jernigan
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Acid-sensing ion channel 1a (ASIC1a) is a voltage-independent, non-selective cation channel that conducts both Na+ and Ca2+. Activation of ASIC1a elicits plasma membrane depolarization and stimulates intracellular Ca2+-dependent signaling pathways in
Externí odkaz:
https://doaj.org/article/5b0acd1eae6c415191754f383d469cd3
Publikováno v:
Antioxidants, Vol 11, Iss 9, p 1680 (2022)
H2S is a gaseous signaling molecule enzymatically produced in mammals and H2S-producing enzymes are expressed throughout the vascular wall. We previously reported that H2S-induced vasodilation is mediated through transient receptor potential cation c
Externí odkaz:
https://doaj.org/article/cf7eeaf4d0df4f37a75e89cc805ce490
Autor:
Selina M. Garcia, Benjamin Matheson, Juan H. Morales-Loredo, Nikki L. Jernigan, Nancy L. Kanagy, Thomas C. Resta, Ross M. Clark, Reza Shekarriz, Laura V. Gonzalez Bosc
Publikováno v:
American journal of physiology. Regulatory, integrative and comparative physiology. 323(6)
Hypoxia is the reduction of alveolar partial pressure of oxygen ([Formula: see text]). Military members and people who practice recreational activities from moderate to high altitudes are at risk for hypoxic exposure. Hypoxemia’s signs and symptoms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca41a08fde734aa2534edc783b7b5b75
https://pubmed.ncbi.nlm.nih.gov/36250874
https://pubmed.ncbi.nlm.nih.gov/36250874
Autor:
Jacob R. Anderson, Emily E. Morin, Kathryn J. Brayer, Sophia Salbato, Laura V. Gonzalez Bosc, Nancy L. Kanagy, Jay S. Naik
Publikováno v:
Physiological Genomics. 55:179-193
The endothelium contains morphologically similar cells throughout the vasculature, but individual cells along the length of a single vascular tree or in different regional circulations function dissimilarly. When observations made in large arteries a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4777eb57ef6bebc0b904ed0a4eef5786
https://doi.org/10.1152/physiolgenomics.00126.2022
https://doi.org/10.1152/physiolgenomics.00126.2022
Autor:
Eric Leslie, Ann L. Gibson, Laura V. Gonzalez Bosc, Christine Mermier, Sean M. Wilson, Michael R. Deyhle
Publikováno v:
High Altitude Medicine & Biology. 24:1-6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc62f751d4375708d9c1fe9f2aced373
https://doi.org/10.1089/ham.2022.0098
https://doi.org/10.1089/ham.2022.0098
Autor:
Levi D. Maston, David T. Jones, Wieslawa Giermakowska, Thomas C. Resta, Juan Ramiro-Diaz, Tamara A. Howard, Nikki L. Jernigan, Lindsay Herbert, Anna A. Maurice, Laura V. Gonzalez Bosc
Publikováno v:
Pulmonary Circulation, Vol 8 (2018)
Interleukin-6 (IL-6) is a pleotropic cytokine that signals through the membrane-bound IL-6 receptor (mIL-6R) to induce anti-inflammatory (“classic-signaling”) responses. This cytokine also binds to the soluble IL-6R (sIL-6R) to promote inflammati
Externí odkaz:
https://doaj.org/article/ce35d513a180422e9248b38507a63b49
Autor:
Amy S. Gardiner, Aleksandr Birg, Jay S. Naik, Nancy L. Kanagy, Laura V. Gonzalez Bosc, Perenkita J Mendiola
Publikováno v:
Comprehensive Physiology. :2467-2488
Hydrogen sulfide (H2 S) is a small, gaseous molecule with poor solubility in water that is generated by multiple pathways in many species including humans. It acts as a signaling molecule in many tissues with both beneficial and pathological effects.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5574146f9d4f648f939e80938c7f6416
https://doi.org/10.1002/cphy.c200036
https://doi.org/10.1002/cphy.c200036
Autor:
Joshua M. Garcia, Perenkita J Mendiola, Gisel Fregoso, Laura V. Gonzalez Bosc, Nancy L. Kanagy, Humberto Morales-Loredo, Carolyn E. Pace, Jay S. Naik, Adelaeda Barrera
Publikováno v:
Am J Physiol Heart Circ Physiol
In sleep apnea, airway obstruction causes intermittent hypoxia (IH). In animal studies, IH-dependent hypertension is associated with loss of vasodilator hydrogen sulfide (H(2)S), and increased H(2)S activation of sympathetic nervous system (SNS) acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3be10230d9fbb7b994b3a1103e6f57f
https://doi.org/10.1152/ajpheart.00672.2019
https://doi.org/10.1152/ajpheart.00672.2019
Autor:
Selina M. Garcia, Tracylyn R. Yellowhair, Rosstin Ahmadian, Lindsay M. Herbert, Laura V. Gonzalez Bosc, Thomas C. Resta, Nikki L. Jernigan
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3de5b47072769f018aebf460d7ae878
https://doi.org/10.1096/fasebj.2022.36.s1.r3935
https://doi.org/10.1096/fasebj.2022.36.s1.r3935
Autor:
Anthony M Szema, Edward Forsyth, Benjamin Ying, Sayyed A Hamidi, John J Chen, Sonya Hwang, Jonathan C Li, Debra Sabatini Dwyer, Juan M Ramiro-Diaz, Wieslawa Giermakowska, Laura V Gonzalez Bosc
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0170606 (2017)
Idiopathic pulmonary fibrosis (IPF) and chronic obstructive pulmonary disease (COPD) are both debilitating lung diseases which can lead to hypoxemia and pulmonary hypertension (PH). Nuclear Factor of Activated T-cells (NFAT) is a transcription factor
Externí odkaz:
https://doaj.org/article/1ac533e34a3b49088da33a0877a6f222