Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Laura Urbanski"'
Autor:
SungHee Park, Mattia Brugiolo, Martin Akerman, Shipra Das, Laura Urbanski, Adam Geier, Anil K. Kesarwani, Martin Fan, Nathan Leclair, Kuan-Ting Lin, Leo Hu, Ian Hua, Joshy George, Senthil K. Muthuswamy, Adrian R. Krainer, Olga Anczuków
Publikováno v:
Cell Reports, Vol 29, Iss 9, Pp 2672-2688.e7 (2019)
Summary: Misregulation of alternative splicing is a hallmark of human tumors, yet to what extent and how it contributes to malignancy are only beginning to be unraveled. Here, we define which members of the splicing factor SR and SR-like families con
Externí odkaz:
https://doaj.org/article/f827df5d6e02402098b1b3fb0fb45114
Autor:
Nathan Leclair, Sunghee Park, Mattia Brugiolo, Brittany Angarola, Laura Urbanski, Marina Yurieva, Olga Anczukow
Publikováno v:
Neurosurgery. 69:96-96
Autor:
Phil Palmer, Nathan K. Leclair, Olga Anczuków, SungHee Park, Laura Urbanski, Brittany Angarola, Mattia Brugiolo, Sangram Keshari Sahu
MYC is dysregulated in >50% of cancers, but direct targeting of MYC has been clinically unsuccessful. Targeting downstream MYC effector pathways represents an attractive alternative. MYC regulates alternative mRNA splicing, a hallmark of cancer, but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d690145a8716039cd2fd7738627fba1
https://doi.org/10.1101/2021.11.24.469558
https://doi.org/10.1101/2021.11.24.469558
Autor:
Laura Urbanski, Mattia Brugiolo, SungHee Park, Brittany L. Angarola, Nathan K. Leclair, Marina Yurieva, Phil Palmer, Sangram Keshari Sahu, Olga Anczuków
Publikováno v:
Cell reports. 41(8)
MYC is dysregulated in50% of cancers, but direct targeting of MYC has been clinically unsuccessful. Targeting downstream MYC effector pathways represents an attractive alternative. MYC regulates alternative mRNA splicing, but the mechanistic links be
Autor:
Brittany Angarola, Olga Anczuków, SungHee Park, Marina Yurieva, Laura Urbanski, Mattia Brugiolo
Publikováno v:
Cancer Research. 81:PD15-07
The oncogenic transcription factor MYC is one of the most frequently altered genes in cancer and is highly dysregulated in aggressive tumor types, including triple negative breast cancer (TNBC). Although direct targeting of MYC or its regulators in h
Autor:
Adrian R. Krainer, Shipra Das, Martin Fan, Nathan K. Leclair, Leo Hu, Olga Anczuków, Laura Urbanski, Adam Geier, SungHee Park, Martin Akerman, Ian Hua, Senthil K. Muthuswamy, Joshy George, Kuan-Ting Lin, Mattia Brugiolo, Anil K. Kesarwani
Publikováno v:
Cell Reports, Vol 29, Iss 9, Pp 2672-2688.e7 (2019)
Summary: Misregulation of alternative splicing is a hallmark of human tumors, yet to what extent and how it contributes to malignancy are only beginning to be unraveled. Here, we define which members of the splicing factor SR and SR-like families con
Autor:
Albert W. Cheng, Laura Urbanski, Mattia Brugiolo, Joshy George, John Travis Hinson, Nathan K. Leclair, Shane C. Lawson, Ketan Thakar, Olga Anczuków, Marina Yurieva, Brenton R. Graveley
Publikováno v:
Mol Cell
The RNA isoform repertoire is regulated by splicing factor (SF) expression, and alterations in SF levels are associated with disease. SFs contain ultraconserved poison exon (PE) sequences that exhibit greater identity across species than nearby codin
Autor:
Shipra Das, Nathan K. Leclair, Mattia Brugiolo, Hua X, Hu C, Martin Fan, Olga Anczuków, Anil K. Kesarwani, Joshy George, Adrian R. Krainer, Laura Urbanski, Kuan-Ting Lin, Senthil K. Muthuswamy, Martin Akerman, Adam Geier, SungHee Park
SUMMARYMisregulation of alternative splicing is a hallmark of human tumors; yet to what extent and how it contributes to malignancy are only beginning to be unraveled. Here, we define which members of the splicing factor SR and SR-like families contr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c23c66a9b46b1e7e9e61b6367a9230b0
https://doi.org/10.1101/634154
https://doi.org/10.1101/634154
Publikováno v:
Wiley interdisciplinary reviews. RNA. 9(4)
Defects in alternative splicing are frequently found in human tumors and result either from mutations in splicing-regulatory elements of specific cancer genes or from changes in the regulatory splicing machinery. RNA splicing regulators have emerged
Academic Librarians and Student Affairs Professionals: An Ethical Collaboration for Higher Education
Autor:
Laura Urbanski Forrest
Publikováno v:
Education Libraries. 28:11
Librarians’ ethical directives point toward a collaborative effort in providing support for students outside the classroom. Academic librarians often focus on collaborative relationships with teaching faculty at institutions of higher education, bu