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pro vyhledávání: '"Laura Tomlinson"'
Autor:
Makin, Laura Tomlinson, author
Publikováno v:
Oxford Studies in Metaethics, Volume 19, 2024.
Externí odkaz:
https://doi.org/10.1093/oso/9780198911876.003.0015
Akademický článek
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Akademický článek
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Autor:
Philip G. Humphreys, Niall A. Anderson, Paul Bamborough, Andrew Baxter, Chun-wa Chung, Rosa Cookson, Peter D. Craggs, Toryn Dalton, Julie C. L. Fournier, Laurie J. Gordon, Heather F. Gray, Matthew W. Gray, Richard Gregory, David J. Hirst, Craig Jamieson, Katherine L. Jones, Hripsimee Kessedjian, David Lugo, Grant McGonagle, Vipulkumar K. Patel, Christopher Patten, Darren L. Poole, Rab K. Prinjha, Cesar Ramirez-Molina, Inmaculada Rioja, Gail Seal, Kayleigh A. J. Stafford, Rishi R. Shah, Daniel Tape, Natalie H. Theodoulou, Laura Tomlinson, Sabri Ukuser, Ian D. Wall, Natalie Wellaway, Gemma White
Publikováno v:
Journal of Medicinal Chemistry. 65:15174-15207
The bromodomain and extra terminal (BET) family of proteins are an integral part of human epigenome regulation, the dysregulation of which is implicated in multiple oncology and inflammatory diseases. Disrupting the BET family bromodomain acetyl-lysi
Autor:
Jack Ayre, Joanna M. Redmond, Giovanni Vitulli, Laura Tomlinson, Richard Weaver, Eleonora Comeo, Cynthia Bosquillon, Michael J. Stocks
Publikováno v:
Journal of Medicinal Chemistry. 65:9802-9818
A major limitation of pulmonary delivery is that drugs can exhibit suboptimal pharmacokinetic profiles resulting from rapid elimination from the pulmonary tissue. This can lead to systemic side effects and a short duration of action. A series of diba
Autor:
Patricia van Hamersveld, Laura Tomlinson, Ishtu Hageman, Ahmed M. I. Elfiky, Sigrid E.M. Heinsbroek, Juan J. Garcia-Vallejo, Jan Verhoeff, Wouter J. de Jonge, Andrew Y. F. Li Yim, Matthew J Bell, Huw D. Lewis, Manon E. Wildenberg, Iris Admiraal, Rab K. Prinjha, Rebecca C. Furze, Richard Gregory, Mohammed Ghiboub, Palwinder K. Mander, Inmaculada Rioja, Manon de Krijger, Olaf Welting, Shafaque Rahman
Publikováno v:
Elfiky, A M I, Ghiboub, M, Li Yim, A Y F, Hageman, I L, Verhoeff, J, de Krijger, M, van Hamersveld, P H P, Welting, O, Admiraal, I, Rahman, S, Garcia-Vallejo, J J, Wildenberg, M E, Tomlinson, L, Gregory, R, Rioja, I, Prinjha, R K, Furze, R C, Lewis, H D, Mander, P K, Heinsbroek, S E M, Bell, M J & de Jonge, W J 2022, ' Carboxylesterase-1 Assisted Targeting of HDAC Inhibitors to Mononuclear Myeloid Cells in Inflammatory Bowel Disease ', Journal of Crohn's and Colitis, vol. 16, no. 4, pp. 668-681 . https://doi.org/10.1093/ecco-jcc/jjab176
Journal of Crohn's and Colitis, 16(4), 668-681. Elsevier
Journal of Crohn's & colitis, 16(4), 668-681. Elsevier
Journal of Crohn's and Colitis, 16(4), 668-681. Elsevier
Journal of Crohn's & colitis, 16(4), 668-681. Elsevier
Background and AimsHistone deacetylase inhibitors [HDACi] exert potent anti-inflammatory effects. Because of the ubiquitous expression of HDACs, clinical utility of HDACi is limited by off-target effects. Esterase-sensitive motif [ESM] technology aim
Autor:
Daniel J, Weston, Mehul, Dave, Kevin, Colizza, Steve, Thomas, Laura, Tomlinson, Richard, Gregory, Claire, Beaumont, Jill, Pirhalla, Gordon J, Dear
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems.
Understanding compound metabolism in early drug discovery aids medicinal chemistry in designing molecules with improved safety and ADME properties. While advancements in metabolite prediction brings increased confidence, structural decisions require
Autor:
Laura Tomlinson
Publikováno v:
Journal of Moral Philosophy. 18:183-185
Autor:
Laura Tomlinson
Publikováno v:
Analysis. 80:403-405
Autor:
Laura Tomlinson
Publikováno v:
Philosophy and Phenomenological Research. 101:704-723