Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Laura Todt"'
1
Standardization of CAR T-Cell Program Implementation in the Sarah Cannon Blood Cancer Network
Autor: Laura Todt, Tonya Cox, C. Fred LeMaistre, Rocky Billups, Betsy Blunk, Therese Dodd
Publikováno v: Biology of Blood and Marrow Transplantation. 25:S421-S422
The Sarah Cannon Blood Cancer Network (SCBCN) consists of hematopoietic cell transplant (HCT) programs, 6 in the US and 3 in the UK, performing more than 1,100 autologous and allogeneic transplants annually with standard quality systems, patient care
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8a80150d02cc94532629cb16c5147bbe
https://doi.org/10.1016/j.bbmt.2018.12.632
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2
Rapid mobilization of functional donor hematopoietic cells without G-CSF using AMD3100, an antagonist of the CXCR4/SDF-1 interaction
Autor: Gary Bridger, Laura Todt, Steven M. Devine, John F. DiPersio, Ravi Vij, Peter Westervelt, Daniel C. Link, Nicholas Fisher, Kiley McGlauchlen, Gary Calandra, Michael P. Rettig, Hollie Devine
Publikováno v: Blood. 112:990-998
Allografts from HLA-matched sibling donors were mobilized and collected without granulocyte colony-stimulating factor (G-CSF) using AMD3100, a direct antagonist of CXCR4/stromal-derived factor 1 (SDF-1/CXCL12). Donors (N = 25) were treated with AMD31
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1be882acdf85b2b30e5ab2ffd60d7439
https://doi.org/10.1182/blood-2007-12-130179
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3
Pharmacokinetics of decitabine administered as a 3-h infusion to patients with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS)
Autor: John F. DiPersio, Ajit K. Shah, Laura Todt, Amanda F. Cashen, Nicholas Fisher
Publikováno v: Cancer Chemotherapy and Pharmacology. 61:759-766
In this study, pharmacokinetics (PK) of decitabine administered as a 3-h intravenous infusion of 15 mg/m2 every 8 h for 3 days (cycles repeated every 6 weeks) was evaluated in patients with MDS or AML. The PK of this dosing regimen was evaluated in s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5831979b4f85f6b819202ae0a5cc77fd
https://doi.org/10.1007/s00280-007-0531-7
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4
Human Progenitor Cells Rapidly Mobilized by AMD3100 Repopulate NOD/SCID Mice with Increased Frequency in Comparison to Cells from the Same Donor Mobilized by Granulocyte Colony Stimulating Factor
Autor: John F. DiPersio, Laura Todt, Louisa Wirthlin, Ryan Lahey, Steven M. Devine, Jesper Bonde, David A. Hess, Timothy P. Craft, Sarah A. Hohm, Jan A. Nolta
Publikováno v: Biology of Blood and Marrow Transplantation. 13(4):398-411
AMD3100 inhibits the interaction between SDF-1 and CXCR4, and rapidly mobilizes hematopoietic progenitors for clinical transplantation. However, the repopulating function of human cells mobilized with AMD3100 has not been characterized in comparison
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::106d251e76be9424b5b2fac841a3d064
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6
HLA-Matched Sibling Donor Stem Cell Mobilization Can Be Safely and Effectively Reduced from a Five Day to a One Day Process by a Direct Antagonist of the CXCR4/SDF-1 Interaction
Autor: Steven M. Devine, John F. DiPersio, Natalie Morris, Gary Bridger, Laura Todt, Ravi Vij, Kiley McLaughlin, Gary Calandra, Daniel C. Link, Nicholas Fisher
Publikováno v: Blood. 108:53-53
The vast majority of matched sibling donor allografts are now procured following mobilization with granulocyte-colony stimulating factor (G-CSF). G-CSF (G) induces stem and progenitor cell mobilization by indirectly disrupting the interaction between
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5d6476244e45d9d2d5cbceed2284dbfc
https://doi.org/10.1182/blood.v108.11.53.53
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7
A Phase I Pharmacokinetic Trial of Decitabine Administered as a 3-Hour Infusion to Patients with Acute Myelogenous Leukemia (AML) or Myelodysplastic Syndrome (MDS)
Autor: Amanda F. Cashen, Laura Todt, John F. DiPersio, Angela Helget, Nicholas Fisher, Ajit K. Shah
Publikováno v: Blood. 106:1854-1854
Background: Decitabine (DacogenTM) is a cytosine analogue that promotes hypomethylation of DNA. Although decitabine has been extensively studied in Phase II and III trials in patients with MDS, relatively limited pharmacokinetic (PK) data is availabl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::80c19db833b03435f34ff9c67c3b4204
https://doi.org/10.1182/blood.v106.11.1854.1854
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8
A Pilot Study Evaluating the Safety and Efficacy of AMD3100 for the Mobilization and Transplantation of HLA-Matched Sibling Donor Hematopoietic Stem Cells in Patients with Advanced Hematological Malignancies
Autor: Leslie A. Andritsos, Laura Todt, Ravi Vij, Daniel C. Link, Gary Calandra, Gary Bridger, Jan A. Nolta, Jesper Bonde, Steven M. Devine, John F. DiPersio, David A. Hess
Publikováno v: Blood. 104:3341-3341
Recent studies suggest G-CSF induces stem cell mobilization by indirectly targeting the interaction between the chemokine stromal derived factor 1 (SDF-1) and its receptor CXCR4. Here we report preliminary results using a direct antagonist of the SDF
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::783dff11701d5b119a308d8410c71ab9
https://doi.org/10.1182/blood.v104.11.3341.3341
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