Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Laura Taylor Alto"'
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e96544 (2014)
CNS inflammation is a hallmark of neurodegenerative disease, and recent studies suggest that the inflammatory response may contribute to neuronal demise. In particular, increased tumor necrosis factor (TNF) signaling is implicated in the pathology of
Externí odkaz:
https://doaj.org/article/a3a81ba1272a45fa8128c1028c510bf3
Autor:
Maria G. Winter, Sing Sing Way, Laura Taylor Alto, James M. Ertelt, Wesley B. Burford, Neal M. Alto, Sebastian E. Winter, Giang Pham, Li-Shu Zhang, Didi Chen
Publikováno v:
Cell Host Microbe
Summary The minimal genetic requirements for microbes to survive within multiorganism communities, including host-pathogen interactions, remain poorly understood. Here, we combined targeted gene mutagenesis with phenotype-guided genetic reassembly to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f23df5aedf578e83861f7b62d93789a
https://pubmed.ncbi.nlm.nih.gov/34536347
https://pubmed.ncbi.nlm.nih.gov/34536347
Autor:
Li-Shu Zhang, Qi Wu, Justin M. Hansen, Maarten F. de Jong, David B. Heisler, Laura Taylor Alto, Neal M. Alto
Publikováno v:
Cell Res
Cell
Cell
Gasdermin B (GSDMB) belongs to a large family of pore forming cytolysins that execute inflammatory cell death programs. While genetic studies have linked GSDMB polymorphisms to human disease, its function in the immunological response to pathogens re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec0f0e2737f922773e0e226533851573
https://pubmed.ncbi.nlm.nih.gov/34341491
https://pubmed.ncbi.nlm.nih.gov/34341491
Autor:
Laura Taylor Alto, Jonathan R. Terman
Publikováno v:
Current biology : CB. 28(9)
Alto and Terman introduce the MICAL family of actin regulatory redox enzymes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fa128c79c53e96e133a0da4c578bf8c
https://pubmed.ncbi.nlm.nih.gov/29738722
https://pubmed.ncbi.nlm.nih.gov/29738722
Autor:
Armin Blesch, Leif A. Havton, Mark H. Tuszynski, James M. Conner, Edmund R. Hollis, Laura Taylor Alto
Publikováno v:
Nature neuroscience
Nature neuroscience, vol 12, iss 9
Nature neuroscience, vol 12, iss 9
A principal objective of spinal cord injury (SCI) research is the restoration of axonal connectivity to denervated targets. We tested the hypothesis that chemotropic mechanisms would guide regenerating spinal cord axons to appropriate brainstem targe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e784ab4554a7de3f9cf6b89f11ed4465
http://europepmc.org/articles/PMC2753201
http://europepmc.org/articles/PMC2753201
Autor:
Paul Lu, Kasper C. D. Roet, Armin Blesch, Giovanni Coppola, Daniel H. Geschwind, Mark H. Tuszynski, Laura Taylor Alto, Shingo Tsukada
Publikováno v:
Experimental neurology. 235(1)
Previous studies indicate that peripheral nerve conditioning lesions significantly enhance central axonal regeneration via modulation of cAMP-mediated mechanisms. To gain insight into the nature and temporal dependence of neural mechanisms underlying
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9102301febad2ece46c0eb967faa14db
https://pubmed.ncbi.nlm.nih.gov/22227059
https://pubmed.ncbi.nlm.nih.gov/22227059
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 5, p e96544 (2014)
PLoS ONE, Vol 9, Iss 5, p e96544 (2014)
CNS inflammation is a hallmark of neurodegenerative disease, and recent studies suggest that the inflammatory response may contribute to neuronal demise. In particular, increased tumor necrosis factor (TNF) signaling is implicated in the pathology of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a52e27c241df4e284327e205b2cc4a1e
https://doi.org/10.1371/journal.pone.0096544
https://doi.org/10.1371/journal.pone.0096544
Publikováno v:
Molecular Neurodegeneration, Vol 4, Iss 1, p 47 (2009)
Molecular Neurodegeneration
Molecular Neurodegeneration
While peripheral immune access to the central nervous system (CNS) is restricted and tightly controlled, the CNS is capable of dynamic immune and inflammatory responses to a variety of insults. Infections, trauma, stroke, toxins and other stimuli are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6124fad362dff23be959ae1b1d52e62