Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Laura Tarnawski"'
Autor:
Alessandro L. Gallina, Urszula Rykaczewska, Robert C. Wirka, April S. Caravaca, Vladimir S. Shavva, Mohamad Youness, Glykeria Karadimou, Mariette Lengquist, Anton Razuvaev, Gabrielle Paulsson-Berne, Thomas Quertermous, Anton Gisterå, Stephen G. Malin, Laura Tarnawski, Ljubica Matic, Peder S. Olofsson
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Objectives and Aims: Vascular smooth muscle cells (VSMCs) are key constituents of both normal arteries and atherosclerotic plaques. They have an ability to adapt to changes in the local environment by undergoing phenotypic modulation. An improved und
Externí odkaz:
https://doaj.org/article/00172a729ab44f2ab228b984782249c7
Autor:
Laura Tarnawski, Peder S Olofsson
Publikováno v:
Clinical & Translational Immunology, Vol 10, Iss 11, Pp n/a-n/a (2021)
Abstract Inflammation is a key process in antimicrobial defence and tissue repair, and failure to properly regulate inflammation can result in tissue damage and death. Neural circuits play important roles throughout the course of an inflammatory resp
Externí odkaz:
https://doaj.org/article/179518de5e504bc497562fa991d05422
Autor:
Ting Yang, Xing-Mei Zhang, Laura Tarnawski, Maria Peleli, Zhengbing Zhuge, Niccolo Terrando, Robert A. Harris, Peder S. Olofsson, Erik Larsson, A. Erik G. Persson, Jon O. Lundberg, Eddie Weitzberg, Mattias Carlstrom
Publikováno v:
Redox Biology, Vol 13, Iss C, Pp 320-330 (2017)
Ischemia-reperfusion (IR) injury involves complex pathological processes in which reduction of nitric oxide (NO) bioavailability is suggested as a key factor. Inorganic nitrate can form NO in vivo via NO synthase-independent pathways and may thus pro
Externí odkaz:
https://doaj.org/article/552ff48a019c4356befc69b5b4fb265c
Autor:
April S. Caravaca, Alessandro L. Gallina, Laura Tarnawski, Kevin J. Tracey, Valentin A. Pavlov, Yaakov A. Levine, Peder S. Olofsson
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Neural reflexes regulate inflammation and electrical activation of the vagus nerve reduces inflammation in models of inflammatory disease. These discoveries have generated an increasing interest in targeted neurostimulation as treatment for chronic i
Externí odkaz:
https://doaj.org/article/86e0529f59b34732b2ba5ff9d509db20
Autor:
Laura Tarnawski, Colin Reardon, April S. Caravaca, Mauricio Rosas-Ballina, Michael W. Tusche, Anna R. Drake, LaQueta K. Hudson, William M. Hanes, Jian Hua Li, William R. Parrish, Kaie Ojamaa, Yousef Al-Abed, Michael Faltys, Valentin A. Pavlov, Ulf Andersson, Sangeeta S. Chavan, Yaakov A. Levine, Tak W. Mak, Kevin J. Tracey, Peder S. Olofsson
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Macrophage cytokine production is regulated by neural signals, for example in the inflammatory reflex. Signals in the vagus and splenic nerves are relayed by choline acetyltransferase+ T cells that release acetylcholine, the cognate ligand for alpha7
Externí odkaz:
https://doaj.org/article/52bcfec8bc364d5ab8731c82b886af1a
Autor:
Laura Tarnawski, Xiaojie Xian, Gustavo Monnerat, Iain C Macaulay, Daniela Malan, Andrew Borgman, Sean M Wu, Bernd K Fleischmann, Stefan Jovinge
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135880 (2015)
In contrast to mature cardiomyocytes which have limited regenerative capacity, pluripotent stem cells represent a promising source for the generation of new cardiomyocytes. The tendency of pluripotent stem cells to form teratomas and the heterogeneit
Externí odkaz:
https://doaj.org/article/7f544021333c48dd93c441c2c22e1878
Autor:
Annica Pontén, Stuart Walsh, Daniela Malan, Xiaojie Xian, Susanne Schéele, Laura Tarnawski, Bernd K Fleischmann, Stefan Jovinge
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e82403 (2013)
Purification of cardiomyocytes from the embryonic mouse heart, embryonic stem (ES) or induced pluripotent stem cells (iPS) is a challenging task and will require specific isolation procedures. Lately the significance of surface markers for the isolat
Externí odkaz:
https://doaj.org/article/9634837056cc484392383db13d4358cf
Autor:
Laura Tarnawski, Vladimir S. Shavva, Eric J. Kort, Zhengbing Zhuge, Ingrid Nilsson, Alessandro L. Gallina, David Martínez-Enguita, Benjamin Heller Sahlgren, Matthew Weiland, April S. Caravaca, Staffan Schmidt, Ping Chen, Katarina Abbas, Fu-Hua Wang, Osman Ahmed, Michael Eberhardson, Anna Färnert, Eddie Weitzberg, Mika Gustafsson, Jan Kehr, Stephen G. Malin, Henrik Hult, Mattias Carlström, Stefan Jovinge, Peder S. Olofsson
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Endothelial dysfunction and impaired vasodilation are linked with adverse cardiovascular events. T lymphocytes expressing choline acetyltransferase (ChAT), the enzyme catalyzing biosynthesis of the vasorelaxant acetylcholine (ACh), regulate vasodilat
Autor:
Dianna Bone, Mona Ahmed, Thuy A Tran, Li Lu, Tetyana Tegnebratt, Ulf Hedin, Laura Tarnawski, Staffan Holmin, Per Eriksson, Peter Damberg, Anton Gisterå, Björn Gustafsson, Kenneth Caidahl
Publikováno v:
International Journal of Nanomedicine. 15:6137-6152
Background Beyond clinical atherosclerosis imaging of vessel stenosis and plaque morphology, early detection of inflamed atherosclerotic lesions by molecular imaging could improve risk assessment and clinical management in high-risk patients. To iden
Publikováno v:
Current Opinion in Neurobiology. 62:115-121
Recent advances in neuroscience and immunology have shown that cholinergic signals are vital in the regulation of inflammation and immunity. Choline acetyltransferase+ (ChAT+) lymphocytes have the capacity to biosynthesize and release acetylcholine,