Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Laura T, Gray"'
Autor:
Lisa R. Volpatti, Rachel P. Wallace, Shijie Cao, Michal M. Raczy, Ruyi Wang, Laura T. Gray, Aaron T. Alpar, Priscilla S. Briquez, Nikolaos Mitrousis, Tiffany M. Marchell, Maria Stella Sasso, Mindy Nguyen, Aslan Mansurov, Erica Budina, Ani Solanki, Elyse A. Watkins, Mathew R. Schnorenberg, Andrew C. Tremain, Joseph W. Reda, Vlad Nicolaescu, Kevin Furlong, Steve Dvorkin, Shann S. Yu, Balaji Manicassamy, James L. LaBelle, Matthew V. Tirrell, Glenn Randall, Marcin Kwissa, Melody A. Swartz, Jeffrey A. Hubbell
Publikováno v:
ACS Central Science, Vol 7, Iss 8, Pp 1368-1380 (2021)
Externí odkaz:
https://doaj.org/article/7d6f01c438c547eb843b88a5c03b6825
Autor:
Priscilla S. Briquez, Sylvie Hauert, Alexandre de Titta, Laura T. Gray, Aaron T. Alpar, Melody A. Swartz, Jeffrey A. Hubbell
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Therapeutic cancer vaccines constitute a valuable tool to educate the immune system to fight tumors and prevent cancer relapse. Nevertheless, the number of cancer vaccines in the clinic remains very limited to date, highlighting the need for further
Externí odkaz:
https://doaj.org/article/9eca26893cb745aa9eca7fe5280c4192
Autor:
Laura T. Gray, Glenn Randall, Mindy Nguyen, Matthew Tirrell, Marcin Kwissa, Steve Dvorkin, Aaron T. Alpar, Balaji Manicassamy, Jeffrey A. Hubbell, Nikolaos Mitrousis, Elyse A. Watkins, James L. LaBelle, Tiffany M. Marchell, Erica Budina, Shann S. Yu, Shijie Cao, Ruyi Wang, Rachel P. Wallace, Michal M. Raczy, Mathew R. Schnorenberg, Kevin Furlong, Vlad Nicolaescu, Lisa R. Volpatti, Andrew C Tremain, Melody A. Swartz, Joseph W. Reda, Aslan Mansurov, Maria Stella Sasso, Priscilla S. Briquez, Ani Solanki
Publikováno v:
ACS Central Science, Vol 7, Iss 8, Pp 1368-1380 (2021)
bioRxiv
article-version (status) pre
article-version (number) 1
ACS Central Science
bioRxiv
article-version (status) pre
article-version (number) 1
ACS Central Science
The COVID-19 pandemic underscores the need for rapid, safe, and effective vaccines. In contrast to some traditional vaccines, nanoparticle-based subunit vaccines are particularly efficient in trafficking antigens to lymph nodes, where they induce pot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00eb21cfa353bc8b2d6928782bffd622
https://doaj.org/article/7d6f01c438c547eb843b88a5c03b6825
https://doaj.org/article/7d6f01c438c547eb843b88a5c03b6825
Autor:
Anna J. Slezak, Aslan Mansurov, Michal M. Raczy, Kevin Chang, Aaron T. Alpar, Abigail L. Lauterbach, Rachel P. Wallace, Rachel K. Weathered, Jorge E.G. Medellin, Claudia Battistella, Laura T. Gray, Tiffany M. Marchell, Suzana Gomes, Melody A. Swartz, Jeffrey A. Hubbell
Publikováno v:
ACS central science. 8(10)
Immune stimulating agents like Toll-like receptor 7 (TLR7) agonists induce potent antitumor immunity but are limited in their therapeutic window due to off-target immune activation. Here, we developed a polymeric delivery platform that binds excess u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dc214c6bc220282e5352a4f2e159aad
https://pubmed.ncbi.nlm.nih.gov/36313164
https://pubmed.ncbi.nlm.nih.gov/36313164
Autor:
Michael JV White, Michal M Raczy, Erica Budina, Eiji Yuba, Ani Solanki, Ha-Na Shim, Zheng Jenny Zhang, Laura T Gray, Shijie Cao, Aaron T. Alpar, Jeffrey A Hubbell
Fibrotic diseases are involved in 45% of deaths in the United States. In particular, fibrosis of the kidney and lung are major public health concerns due to their high prevalence and lack of existing treatment options. Here, we harness the pathophysi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::734a3ff69ce0ee2c4d786bfd0673321c
https://doi.org/10.1101/2022.01.04.474747
https://doi.org/10.1101/2022.01.04.474747
Autor:
Michael White, Michal M. Raczy, Erica Budina, Eiji Yuba, Ani Solanki, Ha-Na Shim, Zheng Jenny Zhang, Laura T. Gray, Shijie Cao, Aaron T. Alpar, Jeffrey A. Hubbell
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04af1fb3f023098287646359eefc0c43
https://doi.org/10.2139/ssrn.4163649
https://doi.org/10.2139/ssrn.4163649
Autor:
Aslan, Mansurov, Peyman, Hosseinchi, Kevin, Chang, Abigail L, Lauterbach, Laura T, Gray, Aaron T, Alpar, Erica, Budina, Anna J, Slezak, Seounghun, Kang, Shijie, Cao, Ani, Solanki, Suzana, Gomes, John-Michael, Williford, Melody A, Swartz, Juan L, Mendoza, Jun, Ishihara, Jeffrey A, Hubbell
Publikováno v:
Nature biomedical engineering. 6(7)
Immune-checkpoint inhibitors have shown modest efficacy against immunologically 'cold' tumours. Interleukin-12 (IL-12)-a cytokine that promotes the recruitment of immune cells into tumours as well as immune cell activation, also in cold tumours-can c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b3841d645e70c071747ec7465ab50a32
https://pubmed.ncbi.nlm.nih.gov/35534574
https://pubmed.ncbi.nlm.nih.gov/35534574
Autor:
Tiffany M. Marchell, Nikolaos Mitrousis, Ruyi Wang, Laura T. Gray, Glenn Randall, Melody A. Swartz, Marcin Kwissa, Rachel P. Wallace, Kevin Furlong, Vlad Nicolaescu, Michal M. Raczy, Mindy Nguyen, Elyse A. Watkins, Balaji Manicassamy, Andrew C Tremain, D. Scott Wilson, Lisa R. Volpatti, Ani Solanki, Steve Dvorkin, Maria Stella Sasso, Shijie Cao, Erica Budina, Aaron T. Alpar, Jeffrey A. Hubbell, Joseph W. Reda, Aslan Mansurov, Priscilla S. Briquez, Shann S. Yu
The SARS-CoV-2 virus has caused an unprecedented global crisis, and curtailing its spread requires an effective vaccine which elicits a diverse and robust immune response. We have previously shown that vaccines made of a polymeric glyco-adjuvant conj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::609dc88b5ac6a29a8652cb34dab4d818
https://doi.org/10.1101/2021.05.20.445060
https://doi.org/10.1101/2021.05.20.445060
Autor:
Ani Solanki, Marcin Kwissa, Andrew C Tremain, Vlad Nicolaescu, Aaron T. Alpar, Nikolaos Mitrousis, Melody A. Swartz, Lisa R. Volpatti, Shann S. Yu, Rachel P. Wallace, Matthew Tirrell, Ruyi Wang, Elyse A. Watkins, Maria Stella Sasso, Tiffany M. Marchell, Balaji Manicassamy, Michal M. Raczy, Shijie Cao, Steve Dvorkin, Joseph W. Reda, Aslan Mansurov, Priscilla S. Briquez, Kevin Furlong, Mathew R. Schnorenberg, Glenn Randall, Erica Budina, Mindy Nguyen, Laura T. Gray, Jeffrey A. Hubbell, James L. LaBelle
A diverse portfolio of SARS-CoV-2 vaccine candidates is needed to combat the evolving COVID-19 pandemic. Here, we developed a subunit nanovaccine by conjugating SARS-CoV-2 Spike protein receptor binding domain (RBD) to the surface of oxidation-sensit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f29e4a1f213b1a04920be54ae8e85047
https://doi.org/10.1101/2021.04.08.438884
https://doi.org/10.1101/2021.04.08.438884
Autor:
Tiffany M. Marchell, Ako Ishihara, Michal M. Raczy, Jun Ishihara, Jeffrey A. Hubbell, Peyman Hosseinchi, Aslan Mansurov, Melody A. Swartz, Aaron T. Alpar, Laura T. Gray, Lambert Potin, John-Michael Williford
Checkpoint-inhibitor (CPI) immunotherapy has achieved remarkable clinical success, yet its efficacy in 'immunologically cold' tumours has been modest. Interleukin-12 (IL-12) is a powerful cytokine that activates the innate and adaptive arms of the im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faad1582775a7a1e09db5a5eac713d07
http://hdl.handle.net/10044/1/83774
http://hdl.handle.net/10044/1/83774