Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Laura Suter-Dick"'
Autor:
Nancy B Hopf, Laura Suter-Dick, Jörg Huwyler, Myriam Borgatta, Lucie Hegg, David Pamies, Hélène Paschoud, Ramya Deepthi Puligilla, Elena Reale, Sophie Werner, Marie-Gabrielle Zurich
Publikováno v:
JMIR Research Protocols, Vol 13, p e50300 (2024)
BackgroundChemicals are not required to be tested systematically for their neurotoxic potency, although they may contribute to the development of several neurological diseases. The absence of systematic testing may be partially explained by the curre
Externí odkaz:
https://doaj.org/article/6e5ba83bc0d641c6be67270524a82d40
Autor:
Lena Mungenast, Ronya Nieminen, Carine Gaiser, Ana Bela Faia-Torres, Jürgen Rühe, Laura Suter-Dick
Publikováno v:
Biomaterials and Biosystems, Vol 11, Iss , Pp 100081- (2023)
Traumatic injury to the spinal cord (SCI) causes the transection of neurons, formation of a lesion cavity, and remodeling of the microenvironment by excessive extracellular matrix (ECM) deposition and scar formation leading to a regeneration-prohibit
Externí odkaz:
https://doaj.org/article/72d083ad991e405aac94b064508dbd41
Autor:
Sarah Heub, Fatemeh Navaee, Daniel Migliozzi, Diane Ledroit, Stéphanie Boder-Pasche, Jonas Goldowsky, Emilie Vuille-Dit-Bille, Joëlle Hofer, Carine Gaiser, Vincent Revol, Laura Suter-Dick, Gilles Weder
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Standardised and high-throughput methods have been developed for the production and experimental handling of some 3D in vitro models. However, adapted analytical tools are still missing for scientists and researchers to fully exploit the pot
Externí odkaz:
https://doaj.org/article/67b79a7869044e69b3482be18cc2959e
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 23, p 15116 (2022)
Low-dose methotrexate (MTX) is a standard therapy for rheumatoid arthritis due to its low cost and efficacy. Despite these benefits, MTX has been reported to cause chronic drug-induced liver injury, namely liver fibrosis. The hallmark of liver fibros
Externí odkaz:
https://doaj.org/article/aa3e8fb28d7c435e8ef396c55f13ea6c
Publikováno v:
CHIMIA, Vol 74, Iss 10, Pp 765-767 (2020)
For over 50 years, Switzerland has been one of the leading countries driving innovation in biotechnology and its industrial applications. Today, some 1,000 biotech companies form a tightly knit, cross-functional network ranging from research through
Externí odkaz:
https://doaj.org/article/d4d9d297058f4210b48f2ad9f4b2f4c6
Autor:
Gabriele Specioso, David Bovard, Filippo Zanetti, Fabio Maranzano, Céline Merg, Antonin Sandoz, Bjoern Titz, Federico Dalcanale, Julia Hoeng, Kasper Renggli, Laura Suter-Dick
Publikováno v:
Bioengineering, Vol 9, Iss 10, p 516 (2022)
There is a lack of physiologically relevant in vitro human kidney models for disease modelling and detecting drug-induced effects given the limited choice of cells and difficulty implementing quasi-physiological culture conditions. We investigated th
Externí odkaz:
https://doaj.org/article/9768d7691aea44418f258a4203caa8d7
Autor:
Lena Mungenast, Fabian Züger, Jasmin Selvi, Ana Bela Faia-Torres, Jürgen Rühe, Laura Suter-Dick, Maurizio R. Gullo
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 19, p 11525 (2022)
Cell cultures aiming at tissue regeneration benefit from scaffolds with physiologically relevant elastic moduli to optimally trigger cell attachment, proliferation and promote differentiation, guidance and tissue maturation. Complex scaffolds designe
Externí odkaz:
https://doaj.org/article/8791a9012c6647be8fd9df8fc61ca541
Autor:
Catherine Jane Messner, Saskia Schmidt, Dilek Özkul, Carine Gaiser, Luigi Terracciano, Stephan Krähenbühl, Laura Suter-Dick
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 18, p 9799 (2021)
Liver fibrosis is characterized by the accumulation of extracellular matrix (ECM) resulting in the formation of fibrous scars. In the clinic, liver biopsies are the standard diagnostic method despite the potential for clinical complications. miRNAs a
Externí odkaz:
https://doaj.org/article/c35d9938063c4d2d8721fcde0e87d708
Autor:
Catherine Jane Messner, Lmar Babrak, Gaia Titolo, Michaela Caj, Enkelejda Miho, Laura Suter-Dick
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 9, p 4372 (2021)
3D cell culture systems are widely used to study disease mechanisms and therapeutic interventions. Multicellular liver microtissues (MTs) comprising HepaRG, hTERT-HSC and THP-1 maintain multicellular interactions and physiological properties required
Externí odkaz:
https://doaj.org/article/ac0ac8876d34471e8896d828f1f06d6f
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0201044 (2018)
Hepatic stellate cells (HSC) orchestrate the deposition of extracellular matrix (ECM) and are the primary effector of liver fibrosis. Several factors, including TGF-β1, PDGF and oxidative stress, have been shown to trigger HSC activation. However, t
Externí odkaz:
https://doaj.org/article/17218222633b49239a553c33ed2527fd