Mislocalization of neuronal tau in the absence of tangle pathology in phosphomutant tau knockin mice

Autor: Brian H. Anderton, Laura Sturdee, Michael P. Coleman, Jean Pierre Brion, Diane P. Hanger, Jonathan Gilley, Teresa Rodriguez-Martin, Amy M. Pooler, Kunie Ando, Anjan Seereeram

Publikováno v: Neurobiology of aging, 39
Gilley, J, Ando, K, Seereeram, A, Rodríguez-Martín, T, Pooler, A M, Sturdee, L, Anderton, B H, Brion, J-P, Hanger, D P & Coleman, M P 2016, ' Mislocalization of neuronal tau in the absence of tangle pathology in phosphomutant tau knockin mice ', Neurobiology of Aging, vol. 39, pp. 1-18 . https://doi.org/10.1016/j.neurobiolaging.2015.11.028

Hyperphosphorylation and fibrillar aggregation of the microtubule-associated protein tau are key features of Alzheimer's disease and other tauopathies. To investigate the involvement of tau phosphorylation in the pathological process, we generated a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cd259b2f04784efb0849659337928c3
https://doi.org/10.1016/j.neurobiolaging.2015.11.028