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Akademický článek

Butyrate reduces epithelial barrier dysfunction induced by the foodborne mycotoxin deoxynivalenol in cell monolayers derived from pig jejunum organoids

Autor: Julie Alberge, Eloïse Mussard, Carine Al-Ayoubi, Corinne Lencina, Christelle Marrauld, Laurent Cauquil, Caroline S. Achard, Ivan Mateos, Imourana Alassane-Kpembi, Isabelle P. Oswald, Laura Soler, Sylvie Combes, Martin Beaumont

Publikováno v: Gut Microbes, Vol 16, Iss 1 (2024)

The foodborne mycotoxin deoxynivalenol (DON) produced by Fusarium species threats animal and human health through disruption of the intestinal barrier. Targeting the gut microbiota and its products appears as a promising strategy to mitigate DON inte

Externí odkaz: https://doaj.org/article/b5d2dac4431c4f16b272c84d1c807dfb

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Akademický článek

Clinical and molecular study of patients with thyroid dyshormogenesis and variants in the thyroglobulin gene

Autor: Mónica Fernández-Cancio, María Antolín, María Clemente, Ariadna Campos-Martorell, Eduard Mogas, Noelia Baz-Redón, Jordi Leno-Colorado, Gemma Comas-Armangué, Elena García-Arumí, Laura Soler-Colomer, Núria González-Llorens, Núria Camats-Tarruella, Diego Yeste

Publikováno v: Frontiers in Endocrinology, Vol 15 (2024)

IntroductionDefects in any thyroid hormone synthesis steps cause thyroid dyshormonogenesis (THD). THD due to thyroglobulin (TG) gene variants is a cause of congenital hypothyroidism (CH) with a wide clinical spectrum, ranging from mild to severe perm

Externí odkaz: https://doaj.org/article/488622cb30184b09bcb312808aad3740

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Akademický článek

Protein expression reveals a molecular sexual identity of avian primordial germ cells at pre-gonadal stages

Autor: Laura Soler, Sabine Alves, Aurélien Brionne, Aurore Jacques, Vanessa Guérin, Maeva Cherif-Feildel, Lucie Combes-Soia, Sophie Fouchécourt, Aurore Thélie, Elisabeth Blesbois, Michael J. McGrew, Valérie Labas, Marina S. Govoroun

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-19 (2021)

Abstract In poultry, in vitro propagated primordial germ cells (PGCs) represent an important tool for the cryopreservation of avian genetic resources. However, several studies have highlighted sexual differences exhibited by PGCs during in vitro prop

Externí odkaz: https://doaj.org/article/d391d850babd4894b90fd60e688afe75

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Akademický článek

Novel variant in HHAT as a cause of different sex development with partial gonadal dysgenesis associated with microcephaly, eye defects, and distal phalangeal hypoplasia of both thumbs: Case report

Autor: Noelia Baz-Redón, Laura Soler-Colomer, Mónica Fernández-Cancio, Sara Benito-Sanz, Marta Garrido, Teresa Moliné, María Clemente, Núria Camats-Tarruella, Diego Yeste

Publikováno v: Frontiers in Endocrinology, Vol 13 (2022)

The palmitoylation of the Hedgehog (Hh) family of morphogens, named sonic hedgehog (SHH), desert hedgehog (DHH), and Indian hedgehog (IHH), is crucial for effective short- and long-range signaling. The hedgehog acyltransferase (HHAT) attaches the pal

Externí odkaz: https://doaj.org/article/454ccb56ce014be6b7ec13e3e295643d

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Akademický článek

The phenotype of the gut region is more stably retained than developmental stage in piglet intestinal organoids

Autor: Eloïse Mussard, Corinne Lencina, Lise Gallo, Céline Barilly, Maryse Poli, Katia Feve, Mikael Albin, Laurent Cauquil, Christelle Knudsen, Caroline Achard, Guillaume Devailly, Laura Soler, Sylvie Combes, Martin Beaumont

Publikováno v: Frontiers in Cell and Developmental Biology, Vol 10 (2022)

Intestinal organoids are innovative in vitro tools to study the digestive epithelium. The objective of this study was to generate jejunum and colon organoids from suckling and weaned piglets in order to determine the extent to which organoids retain

Externí odkaz: https://doaj.org/article/52c878a27bc04267a7d1c3ac9a5d8dde

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Akademický článek

Precisión diagnóstica del índice de masa triponderal (kg/m3) para identificar el fenotipo de riesgo metabólico en pacientes obesos

Autor: Diego Yeste, María Clemente, Ariadna Campos, Anna Fábregas, Eduard Mogas, Laura Soler, Antonio Carrascosa

Publikováno v: Anales de Pediatría, Vol 94, Iss 2, Pp 68-74 (2021)

Resumen: Introducción: El fenotipo obeso metabólicamente sano (FOMS) define a los pacientes obesos que tienen preservada la sensibilidad a la insulina y que no presentan complicaciones metabólicas. Este fenotipo se asocia a menor riesgo de padecer

Externí odkaz: https://doaj.org/article/8ae694d7f2c947bd8cc1c282f721265f

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Akademický článek

Diagnostic accuracy of the tri-ponderal mass index in identifying the unhealthy metabolic obese phenotype in obese patients

Autor: Diego Yeste, María Clemente, Ariadna Campos, Anna Fábregas, Eduard Mogas, Laura Soler, Antonio Carrascosa

Publikováno v: Anales de Pediatría (English Edition), Vol 94, Iss 2, Pp 68-74 (2021)

Introduction: The metabolically healthy obese phenotype (FOMS) defines obese patients who have preserved insulin sensitivity and absence of metabolic complications. This phenotype is associated with a lower risk of cardiovascular disease and type 2 d

Externí odkaz: https://doaj.org/article/66f3bafdd49a4a44a309842379486752

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Akademický článek

Proteomic Changes Associated With Sperm Fertilizing Ability in Meat-Type Roosters

Autor: Anaïs Vitorino Carvalho, Laura Soler, Aurore Thélie, Isabelle Grasseau, Luiz Cordeiro, Daniel Tomas, Ana-Paula Teixeira-Gomes, Valérie Labas, Elisabeth Blesblois

Publikováno v: Frontiers in Cell and Developmental Biology, Vol 9 (2021)

The molecular basis of male fertility remains unclear, especially in chickens, where decades of genetic selection increased male fertility variability as a side effect. As transcription and translation are highly limited in sperm, proteins are key mo

Externí odkaz: https://doaj.org/article/82f23a675eec47b1a381d66b914e7829

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