Emergence of De Novo Conditions Following Remission of Cushing Syndrome: A Case Report and Scoping Review

Autor: Noémie Desgagnés, Laura Senior, Daniel Vis, Katayoun Alikhani, Kirstie Lithgow

Publikováno v: Endocrinology, Diabetes & Metabolism, Vol 7, Iss 3, Pp n/a-n/a (2024)

ABSTRACT Objective Onset and exacerbation of autoimmune, inflammatory or steroid‐responsive conditions have been reported following the remission of Cushing syndrome, leading to challenges in distinguishing a new condition versus expected symptomat

Externí odkaz: https://doaj.org/article/a7e2f9d0a649484689eeb01f44f6b63f

Emergence of De-novo Steroid-Responsive Conditions Following Remission of Cushing's Syndrome: A Case Report and Scoping Review

Autor: Noemie Desgagnes, Laura Senior, Kirstie Lithgow

Publikováno v: Endocrine Abstracts.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3de223ba57b8c25e88bb7efd010909ea
https://doi.org/10.1530/endoabs.90.p701

Kv2.1 Clustering Contributes to Insulin Exocytosis and Rescues Human β-Cell Dysfunction

Autor: Dafna Greitzer-Antes, John Maringa Githaka, Mette V. Jensen, Nicolas Touret, Gregory Plummer, Xiao-Qing Dai, Christopher B. Newgard, Jocelyn E. Manning Fox, Patrick E. MacDonald, Laura Senior, Herbert Y. Gaisano, Austin Bautista, Jianyang Fu, Kunimasa Suzuki

Publikováno v: Diabetes

Insulin exocytosis is regulated by ion channels that control excitability and Ca2+ influx. Channels also play an increasingly appreciated role in microdomain structure. In this study, we examine the mechanism by which the voltage-dependent K+ (Kv) ch

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::957995e25eec92ea22d80fa4e24e6742
https://doi.org/10.2337/db16-1170

Bioinspired Silicification Reveals Structural Detail in Self-Assembled Peptide Cages

Autor: Guto G. Rhys, Wei-Feng Xue, Johanna M. Galloway, Robert L. Harniman, Joseph L. Beesley, Judith Mantell, Derek N. Woolfson, Majid Mosayebi, Tanniemola B. Liverpool, Lorna Hodgson, Paul Verkade, Noah Linden, Laura Senior, Jennifer Coombs, Jordan M. Fletcher, Paul Curnow

Publikováno v: Galloway, J M, Senior, L, Fletcher, J M, Beesley, J L, Hodgson, L R, Harniman, R L, Mantell, J M, Coombs, J, Rhys, G G, Xue, W-F, Mosayebi, M, Linden, N, Liverpool, T B, Curnow, P, Verkade, P & Woolfson, D N 2018, ' Bioinspired Silicification Reveals Structural Detail in Self-Assembled Peptide Cages ', ACS Nano, vol. 12, no. 2, pp. 1420–1432 . https://doi.org/10.1021/acsnano.7b07785
ACS Nano

Understanding how molecules in self-assembled soft-matter nanostructures are organized is essential for improving the design of next-generation nanomaterials. Imaging these assemblies can be challenging and usually requires processing, e.g. staining

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d4adb2ef9dbc878edcc93d35427cb2d
https://hdl.handle.net/1983/597ff710-325f-4d82-ac3f-003afee7dba4

Expression, purification and reconstitution of the 4-hydroxybenzoate transporter PcaK from Acinetobacter sp. ADP1

Autor: Christian Pernstich, Laura Senior, Katherine A. MacInnes, Marc Forsaith, Paul Curnow

Publikováno v: Protein Expression and Purification

Highlights • The aromatic acid transporter PcaK was recombinantly expressed and purified. • PcaK is a stable homotrimer in n-dodecyl-β-d-maltoside. • A reconstituted assay shows asymmetric transport. • The electrical component of the proton

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5577effe87c18f787843519562f8ac8f
https://pubmed.ncbi.nlm.nih.gov/24907408