Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Laura Segall"'
Publikováno v:
Journal of Biological Chemistry. 282:33691-33697
The cytoplasmic N terminus of the Na,K-ATPase is a highly charged and flexible structure that comprises three predicted helical regions including H1 spanning residues 27 to 33 and H2 spanning residues 42 to 50. Previous deletion mutagenesis experimen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::038fa631d90ea458d3b976eb5ae273b5
https://doi.org/10.1074/jbc.m705899200
https://doi.org/10.1074/jbc.m705899200
Publikováno v:
Annals of the New York Academy of Sciences. 986:58-62
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::638fadf8679cbcf47cb762a67484fdc3
https://doi.org/10.1111/j.1749-6632.2003.tb07139.x
https://doi.org/10.1111/j.1749-6632.2003.tb07139.x
Publikováno v:
Journal of Biological Chemistry. 277:35202-35209
The deletion of 32 residues from the N terminus of the alpha1 catalytic subunit of the rat Na,K-ATPase (mutant alpha1M32) shifts the E(1)/E(2) conformational equilibrium toward E(1), and the combination of this deletion with mutation E233K in the M2-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::148985467981f942af952bb5b8298c3e
https://doi.org/10.1074/jbc.m206115200
https://doi.org/10.1074/jbc.m206115200
Mechanistic Basis for Kinetic Differences between the Rat α1, α2, and α3 Isoforms of the Na,K-ATPase
Publikováno v:
Journal of Biological Chemistry. 276:31535-31541
Previous studies showed that the α1, α2, and α3 isoforms of the catalytic subunit of the Na,K-ATPase differ in their apparent affinities for the ligands ATP, Na+, and K+. For the rat isoforms transfected into HeLa cells,K′ATP for ATP binding at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02ddc20c548657ce402cf5bb9403f8cc
https://doi.org/10.1074/jbc.m103720200
https://doi.org/10.1074/jbc.m103720200
Publikováno v:
Journal of Biological Chemistry. 273:16146-16154
The mechanism by which glucose stimulates insulin secretion from the pancreatic islets of Langerhans is incompletely understood. It has been suggested that malonyl-CoA plays a regulatory role by inhibiting fatty acid oxidation and promoting accumulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a5842e0b68f37fbfa24ffd623ae3930
https://doi.org/10.1074/jbc.273.26.16146
https://doi.org/10.1074/jbc.273.26.16146
Publikováno v:
médecine/sciences. 22:341-343
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e0dc128dc542ad58cdce582c3847b76
https://doi.org/10.1051/medsci/2006224341
https://doi.org/10.1051/medsci/2006224341
Autor:
Rosemarie Scanzano, Maija Wessman, Aarno Palotie, J. Jay Gargus, Laura Segall, Mari A. Kaunisto, Rhoda Blostein
Publikováno v:
The Journal of biological chemistry. 279(42)
A number of missense mutations in the ATP1A2 gene, which encodes the Na,K-ATPase alpha2 subunit, have been identified in familial hemiplegic migraine with aura. Loss of function and haploinsufficiency have been the suggested mechanisms in mutants for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c761b8b0b1b08560407ff8aa5198cbe
https://pubmed.ncbi.nlm.nih.gov/15308625
https://pubmed.ncbi.nlm.nih.gov/15308625
Publikováno v:
The Journal of biological chemistry. 278(11)
We showed earlier that the kinetic behavior of the alpha2 isoform of the Na,K-ATPase differs from the ubiquitous alpha1 isoform primarily by a shift in the steady-state E(1)/E(2) equilibrium of alpha2 in favor of E(1) form(s). The aim of the present
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fffa3ba53612b5dd68a55ed8f2a5a29
https://pubmed.ncbi.nlm.nih.gov/12529322
https://pubmed.ncbi.nlm.nih.gov/12529322
Autor:
Raphaël Roduit, Marc Prentki, Enrique Roche, Laura Segall, Françoise Assimacopoulos-Jeannet, Johane Morin, Frédéric Massé, Christopher B. Newgard
Publikováno v:
The Journal of biological chemistry. 275(46)
To better understand the action of glucose on fatty acid metabolism in the beta-cell and the link between chronically elevated glucose or fatty acids and beta-cell decompensation in adipogenic diabetes, we investigated whether glucose regulates perox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9107280dc3f297422fdba6c1d4e6e41e
https://pubmed.ncbi.nlm.nih.gov/10967113
https://pubmed.ncbi.nlm.nih.gov/10967113
Autor:
Marc Prentki, Barbara E. Corkey, Victoria Esser, Gordon C. Yaney, S Thumelin, Asish K. Saha, J. Denis McGarry, Françoise Assimacopoulos Jeannet, Enrique Roche, Laura Segall, Salah Farfari, Thierry Brun, Lee A. Witters
Publikováno v:
Experimental and Clinical Endocrinology & Diabetes. 105:89-90
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91e1c7163bd82f9c348374b3443e9a77
https://doi.org/10.1055/s-0029-1211915
https://doi.org/10.1055/s-0029-1211915