Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Laura Seestaller-Wehr"'
Autor:
Junping Jing, Laura Bover, C Ian Mockridge, Kerry L Cox, Mark S Cragg, Tatyana Inzhelevskaya, Chris A Penfold, Vikki English, Jane E Willoughby, Hong Shi, Peter J Morley, Heather Jackson, Roopa Srinivasan, Tom Murray, Axel Hoos, Paul Bojczuk, James Smothers, Niranjan Yanamandra, Lang Dou, Sabyasachi Bhattacharya, Laura Seestaller-Wehr, David Kilian, Kui S Voo, Mel John, Heather Niederer, Andrew J Shepherd, Laura Hook, Stephanie Hopley, Sara J Brett, Christopher Hopson, Elaine Paul, Stephen L Martin
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 7 (2024)
Background OX40 has been widely studied as a target for immunotherapy with agonist antibodies taken forward into clinical trials for cancer where they are yet to show substantial efficacy. Here, we investigated potential mechanisms of action of anti-
Externí odkaz:
https://doaj.org/article/1d4a1e220c0f453894379600a08cb4a4
Autor:
Jong W Yu, Sabyasachi Bhattacharya, Niranjan Yanamandra, David Kilian, Hong Shi, Sapna Yadavilli, Yuliya Katlinskaya, Heather Kaczynski, Michael Conner, William Benson, Ashleigh Hahn, Laura Seestaller-Wehr, Meixia Bi, Nicholas J Vitali, Lyuben Tsvetkov, Wendy Halsey, Ashley Hughes, Christopher Traini, Hui Zhou, Junping Jing, Tae Lee, David J Figueroa, Sara Brett, Christopher B Hopson, James F Smothers, Axel Hoos, Roopa Srinivasan
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0206223 (2018)
Mouse syngeneic tumor models are widely used tools to demonstrate activity of novel anti-cancer immunotherapies. Despite their widespread use, a comprehensive view of their tumor-immune compositions and their relevance to human tumors has only begun
Externí odkaz:
https://doaj.org/article/9e5e09f3952c4542877ca7afcf5e271e
Autor:
Axel Hoos, James Smothers, Shu Zhang, Junping Jing, Lyuben Tsvetkov, Chris Hopson, Shu-Yun Zhang, Laura Seestaller-Wehr, Jingsong Yang, Tianqian Zhang, Sapna Yadavilli, Hong Shi, Stephen Eastman, Patrick A. Mayes, Li Liu
Supplementary Materials and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c132032d92e87d5e6b477ea82f956e1
https://doi.org/10.1158/1078-0432.22461912
https://doi.org/10.1158/1078-0432.22461912
Autor:
Axel Hoos, James Smothers, Shu Zhang, Junping Jing, Lyuben Tsvetkov, Chris Hopson, Shu-Yun Zhang, Laura Seestaller-Wehr, Jingsong Yang, Tianqian Zhang, Sapna Yadavilli, Hong Shi, Stephen Eastman, Patrick A. Mayes, Li Liu
Purpose: To assess the immunologic effects of dabrafenib and trametinib in vitro and to test whether trametinib potentiates or antagonizes the activity of immunomodulatory antibodies in vivo.Experimental Design: Immune effects of dabrafenib and trame
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::661aaed347926a54cf4ec666b3845e7f
https://doi.org/10.1158/1078-0432.c.6524868.v1
https://doi.org/10.1158/1078-0432.c.6524868.v1
Autor:
Axel Hoos, James Smothers, Shu Zhang, Junping Jing, Lyuben Tsvetkov, Chris Hopson, Shu-Yun Zhang, Laura Seestaller-Wehr, Jingsong Yang, Tianqian Zhang, Sapna Yadavilli, Hong Shi, Stephen Eastman, Patrick A. Mayes, Li Liu
Supplementary figure 2. Tumor gene expression changes measured by RT-PCR from mice treated with trametinib (T) in combination with the immunomodulator-targeting PD1 in the CT26 murine syngeneic model.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6adc6344fb2c29f4cd0bb83e6b434a00
https://doi.org/10.1158/1078-0432.22461906.v1
https://doi.org/10.1158/1078-0432.22461906.v1
Autor:
Axel Hoos, James Smothers, Shu Zhang, Junping Jing, Lyuben Tsvetkov, Chris Hopson, Shu-Yun Zhang, Laura Seestaller-Wehr, Jingsong Yang, Tianqian Zhang, Sapna Yadavilli, Hong Shi, Stephen Eastman, Patrick A. Mayes, Li Liu
Supplementary figure 1. Tumor growth kinetics in individual mice treated with trametinib (T) in combination with the immunomodulator-targeting PD1 in the CT26 murine syngeneic model.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27d034d716bb8479289c704eae1ae6b4
https://doi.org/10.1158/1078-0432.22461909.v1
https://doi.org/10.1158/1078-0432.22461909.v1
Autor:
Axel Hoos, James Smothers, Shu Zhang, Junping Jing, Lyuben Tsvetkov, Chris Hopson, Shu-Yun Zhang, Laura Seestaller-Wehr, Jingsong Yang, Tianqian Zhang, Sapna Yadavilli, Hong Shi, Stephen Eastman, Patrick A. Mayes, Li Liu
Supplementary tables S1-S6. Tumor gene expression data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49df5c367a4323164d8cf2bdc745816b
https://doi.org/10.1158/1078-0432.22461903.v1
https://doi.org/10.1158/1078-0432.22461903.v1
Autor:
Ariamala Gopalsamy, Mengxiao Shi, Barbara Stauffer, Ramesh Bahat, Julia Billiard, Helga Ponce-de-Leon, Laura Seestaller-Wehr, Shoichi Fukayama, Annamarie Mangine, Robert Moran, Girija Krishnamurthy, Peter Bodine
Publikováno v:
Journal of Medicinal Chemistry; Dec2008, Vol. 51 Issue 24, p7670-7672, 3p