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Autor:
Laura Scharlibbe, Klaudia Giehl, Andre Menke, Dirk Lohfink, Julia R. Seiz, Hendrik Ungefroren, Johannes Klinke, Marisa Heipel
Publikováno v:
Biological Chemistry. 401:517-531
Rac1 is a ubiquitously expressed Rho GTPase and an important regulator of the actin cytoskeleton. Its splice variant Rac1b exhibits a 19-amino acid (aa) in-frame insertion and is predominantly active. Both proteins were described in tumorigenesis or